iNOS‐inhibitor driven neuroprotection in a porcine retina organ culture model

Autor: Hurst, José, Mueller‐Buehl, Ana Maria, Hofmann, Lisa, Kuehn, Sandra, Herms, Fenja, Schnichels, Sven, Joachim, Stephanie Christine

Publikováno v: Journal of Cellular and Molecular Medicine

Nitrite oxide plays an important role in the pathogenesis of various retinal diseases, especially when hypoxic processes are involved. This degeneration can be simulated by incubating porcine retinal explants with CoCl2. Here, the therapeutic potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a9f7cc280c3494a9b7fb387ce09228b
http://europepmc.org/articles/PMC7171393

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Reduced Retinal Degeneration in an Oxidative Stress Organ Culture Model through an iNOS-Inhibitor.

Autor: Mueller-Buehl AM; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany., Tsai T; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany., Hurst J; Center for Ophthalmology Tübingen, University Eye Hospital Tübingen, 72076 Tübingen, Germany., Theiss C; Department of Cytology, Institute of Anatomy, Ruhr-University Bochum, 44801 Bochum, Germany., Peters L; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany., Hofmann L; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany., Herms F; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.; Clinic for Small Mammals, Reptiles and Birds, University of Veterinary Medicine, 30559 Hannover, Germany., Kuehn S; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany., Schnichels S; Center for Ophthalmology Tübingen, University Eye Hospital Tübingen, 72076 Tübingen, Germany., Joachim SC; Experimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.

Publikováno v: Biology [Biology (Basel)] 2021 Apr 28; Vol. 10 (5). Date of Electronic Publication: 2021 Apr 28.