Zobrazeno 1 - 10
of 559
pro vyhledávání: '"Hermona Soreq"'
Autor:
Serafima Dubnov, Estelle R. Bennett, Nadav Yayon, Or Yakov, David A. Bennett, Sudha Seshadri, Elliott Mufson, Yonat Tzur, David Greenberg, Makoto Kuro-o, Iddo Paldor, Carmela R. Abraham, Hermona Soreq
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Overexpression of the longevity gene Klotho prolongs lifespan, while its knockout shortens lifespan and impairs cognition via perturbation of myelination and synapse formation. However, comprehensive analysis of Klotho knockout effects on ma
Externí odkaz:
https://doaj.org/article/3ebc2e4dc2b14899a640933ae8c12b98
Autor:
Fabian Kern, Thomas Kuhn, Nicole Ludwig, Martin Simon, Laura Gröger, Natalie Fabis, Ernesto Aparicio-Puerta, Abdulrahman Salhab, Tobias Fehlmann, Oliver Hahn, Annika Engel, Viktoria Wagner, Marcus Koch, Katarzyna Winek, Hermona Soreq, Irina Nazarenko, Gregor Fuhrmann, Tony Wyss-Coray, Eckart Meese, Verena Keller, Matthias W. Laschke, Andreas Keller
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 482-494 (2023)
Previous work on murine models and humans demonstrated global as well as tissue-specific molecular ageing trajectories of RNAs. Extracellular vesicles (EVs) are membrane vesicles mediating the horizontal transfer of genetic information between differ
Externí odkaz:
https://doaj.org/article/c4f989c3cc3d47828f08997c492f2092
Autor:
Yonat Tzur, Katarzyna Winek, Nimrod Madrer, Serafima Dubnov, Estelle R. Bennett, David S. Greenberg, Geula Hanin, Asaad Gammal, Joseph Tam, Isaiah T. Arkin, Iddo Paldor, Hermona Soreq
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101856- (2024)
Objective: Non-alcoholic fatty liver disease (NAFLD) involves hepatic accumulation of intracellular lipid droplets via incompletely understood processes. Here, we report distinct and cooperative NAFLD roles of LysTTT-5′tRF transfer RNA fragments an
Externí odkaz:
https://doaj.org/article/10e908bb94994ad399d128f2b5fc3d68
Autor:
Ivan Arisi, Leonardo Malimpensa, Valeria Manzini, Rossella Brandi, Tommaso Gosetti di Sturmeck, Chiara D’Amelio, Sebastiano Crisafulli, Gina Ferrazzano, Daniele Belvisi, Francesca Malerba, Rita Florio, Esterina Pascale, Hermona Soreq, Marco Salvetti, Antonino Cattaneo, Mara D’Onofrio, Antonella Conte
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and objectivesMultiple sclerosis (MS) is a chronic, progressive neurological disease characterized by early-stage neuroinflammation, neurodegeneration, and demyelination that involves a spectrum of heterogeneous clinical manifestations in
Externí odkaz:
https://doaj.org/article/fd58ef36b5ed4df88fb3c4411a2e547d
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
To outline the complex biological rhythms underlying the time-to-action of goal-oriented behavior in the adult brain, we employed a Boolean Algebra model based on Control Systems Theory. This suggested that “timers” of the brain reflect a metabol
Externí odkaz:
https://doaj.org/article/abba8fea9b6247b5b6eb74d6804925e1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Externí odkaz:
https://doaj.org/article/947f4670cbc44850b672a4bfb4a143e6
Autor:
Muslum Gok, Nimrod Madrer, Tamara Zorbaz, Estelle R. Bennett, David Greenberg, David A. Bennett, Hermona Soreq
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) are involved in modulating cholinergic signaling, but their roles in Alzheimer’s and Parkinson’s diseases (AD and PD) remain unclear. We identified a higher frequency of the functiona
Externí odkaz:
https://doaj.org/article/c2b9d62a14fa477fa1232ffcfb5df553
Publikováno v:
Cells, Vol 12, Iss 13, p 1794 (2023)
Anxiety and metabolic impairments are often inter-related, but the underlying mechanisms are unknown. To seek RNAs involved in the anxiety disorder–metabolic disorder link, we subjected zebrafish larvae to caffeine-induced anxiety or high-fat diet
Externí odkaz:
https://doaj.org/article/15b25edfed7545d98c4a72824fb9e56d
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100193- (2020)
Summary: Cholinergic neurons control numerous primate-specific and sexually dimorphic brain functions. Here, we present our differentiation protocol for the closely related human female and male neuroblastoma-originated cell lines LA-N-2 and LA-N-5.
Externí odkaz:
https://doaj.org/article/9641ead8dc8445d3961c27c7bea84d8e
Autor:
Mor Hanan, Alon Simchovitz, Nadav Yayon, Shani Vaknine, Roni Cohen‐Fultheim, Miriam Karmon, Nimrod Madrer, Talia Miriam Rohrlich, Moria Maman, Estelle R Bennett, David S Greenberg, Eran Meshorer, Erez Y Levanon, Hermona Soreq, Sebastian Kadener
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
Externí odkaz:
https://doaj.org/article/c544f8cb16f84f918a532608ddf55efe