Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Hermie J M, Harmsen"'
Autor:
Lieske Wekema, Sam Schoenmakers, Nicole Schenkelaars, Anne Laskewitz, Lei Liu, Lisa Walters, Hermie J. M. Harmsen, Régine P. M. Steegers-Theunissen, Marijke M. Faas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMaternal obesity poses risks for both mother and offspring during pregnancy, with underlying mechanisms remaining largely unexplored. Obesity is associated with microbial gut dysbiosis and low-grade inflammation, and also the diet has a m
Externí odkaz:
https://doaj.org/article/802e251306264652bbc31453e7402a39
Autor:
Shuyan Zhang, J. Casper Swarte, Ranko Gacesa, Tim J. Knobbe, Daan Kremer, Bernadien H. Jansen, Martin H. de Borst, Hermie J. M. Harmsen, Michiel E. Erasmus, Erik A. M. Verschuuren, Stephan J. L. Bakker, C. Tji Gan, Rinse K. Weersma, Johannes R. Björk
Publikováno v:
mSystems, Vol 9, Iss 6 (2024)
ABSTRACT Gut dysbiosis has been associated with impaired outcomes in liver and kidney transplant recipients, but the gut microbiome of lung transplant recipients has not been extensively explored. We assessed the gut microbiome in 64 fecal samples fr
Externí odkaz:
https://doaj.org/article/33dfc51e43fa4a4fbd184b36da11afaa
Autor:
Asier Fernández-Pato, Trishla Sinha, Ranko Gacesa, Sergio Andreu-Sánchez, Milla F. Brandao Gois, Jody Gelderloos-Arends, Dianne B. H. Jansen, Marloes Kruk, Martin Jaeger, Leo A. B. Joosten, Mihai G. Netea, Rinse K. Weersma, Cisca Wijmenga, Hermie J. M. Harmsen, Jingyuan Fu, Alexandra Zhernakova, Alexander Kurilshikov
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The lack of standardization in the methods of DNA extraction from fecal samples represents the major source of experimental variation in the microbiome research field. In this study, we aimed to compare the metagenomic profiles and microbiom
Externí odkaz:
https://doaj.org/article/52385fca2f7241a7beafe6bc3f4fd066
Autor:
Shixian Hu, Arno R. Bourgonje, Ranko Gacesa, Bernadien H. Jansen, Johannes R. Björk, Amber Bangma, Iwan J. Hidding, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen, Eleonora A. M. Festen, Arnau Vich Vila, Lieke M. Spekhorst, Rinse K. Weersma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Disrupted host-microbe interactions at the mucosal level are key to the pathophysiology of IBD. This study aimed to comprehensively examine crosstalk between mucosal gene expression and microbiota in patients with IBD. To study tissue-specif
Externí odkaz:
https://doaj.org/article/7d585f4cd17d4027b8c1cce58bfea380
Autor:
J. Casper Swarte, Tim J. Knobbe, Johannes R. Björk, Ranko Gacesa, Lianne M. Nieuwenhuis, Shuyan Zhang, Arnau Vich Vila, Daan Kremer, Rianne M. Douwes, Adrian Post, Evelien E. Quint, Robert A. Pol, Bernadien H. Jansen, TransplantLines investigators, Martin H. de Borst, Vincent E. de Meijer, Hans Blokzijl, Stefan P. Berger, Eleonora A. M. Festen, Alexandra Zhernakova, Jingyuan Fu, Hermie J. M. Harmsen, Stephan J. L. Bakker, Rinse K. Weersma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Kidney transplant recipients (KTR) have impaired health-related quality of life (HRQoL) and suffer from intestinal dysbiosis. Increasing evidence shows that gut health and HRQoL are tightly related in the general population. Here, we investi
Externí odkaz:
https://doaj.org/article/cdeb8a6b39384ab38c6f1bc5cddf08f1
Autor:
Raphael R. Fagundes, Gabriela Bravo-Ruiseco, Shixian Hu, Sarah J. Kierans, Rinse K. Weersma, Cormac T. Taylor, Gerard Dijkstra, Hermie J. M. Harmsen, Klaas Nico Faber
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionIntestinal epithelial cells produce interleukin-18 (IL-18), a key factor in promoting epithelial barrier integrity. Here, we analyzed the potential role of gut bacteria and the hypoxia-inducible factor 1α (HIF1α) pathway in regulating m
Externí odkaz:
https://doaj.org/article/5f37fa2f42fd405ca3fe8ff2670a47dc
Autor:
Hannah R. Wardill, Ana Rita Da Silva Ferreira, Himanshu Kumar, Emma H. Bateman, Courtney B. Cross, Joanne M. Bowen, Rick Havinga, Hermie J. M. Harmsen, Jan Knol, Bram Dorresteijn, Miriam van Dijk, Jeroen van Bergenhenegouwen, Wim J. E. Tissing
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-11 (2023)
Abstract Cytotoxicity (i.e. cell death) is the core mechanism by which chemotherapy induces its anti-cancer effects. Unfortunately, this same mechanism underpins the collateral damage it causes to healthy tissues. The gastrointestinal tract is highly
Externí odkaz:
https://doaj.org/article/482db40cb7d744d09d27ea7752343e9d
Autor:
Jarno Hakkers, Lei Liu, Diederik F. M. Hentenaar, Gerry M. Raghoebar, Arjan Vissink, Henny J. A. Meijer, Lisa Walters, Hermie J. M. Harmsen, Yvonne C. M. de Waal
Publikováno v:
Dentistry Journal, Vol 12, Iss 1, p 20 (2024)
The objective was to assess the effect of peri-implantitis surgery on the peri-implant microbiome with a follow-up of one year. A total of 25 peri-implantitis patients in whom non-surgical treatment has failed to solve peri-implantitis underwent rese
Externí odkaz:
https://doaj.org/article/b1d3eb23b666465185fd8695c3a66d6f
Autor:
Mèlanie V. Bénard, Iñaki Arretxe, Koen Wortelboer, Hermie J. M. Harmsen, Mark Davids, Clara M. A. de Bruijn, Marc A. Benninga, Floor Hugenholtz, Hilde Herrema, Cyriel Y. Ponsioen
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2238 (2023)
Fecal microbiota transplantation (FMT) is under investigation for several indications, including ulcerative colitis (UC). The clinical success of FMT depends partly on the engraftment of viable bacteria. Because the vast majority of human gut microbi
Externí odkaz:
https://doaj.org/article/a30de248f75e4d489c38dd78c03a596f
Autor:
Arezoo Shajiei, Matthijs S. Berends, Christian F. Luz, Jos A. van Oers, Hermie J. M. Harmsen, Piet Vos, Rob Klont, Bert G. Loef, Auke C. Reidinga, Laura Bormans-Russell, Kitty Linsen, Tom Dormans, Martine Otten, Akke van der Bij, Albertus Beishuizen, Dylan W. de Lange, Evelien de Jong, Maarten W. Nijsten
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundIn the previously reported SAPS trial (https://clinicaltrials.gov/ct2/show/NCT01139489), procalcitonin-guidance safely reduced the duration of antibiotic treatment in critically ill patients. We assessed the impact of shorter antibiotic tre
Externí odkaz:
https://doaj.org/article/04a0bd7157ca4fbd9dd11b6a27457224