Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hermi Sumatoh"'
Autor:
Elaine Lai-Han Leung, Run-Ze Li, Xing-Xing Fan, Lily Yan Wang, Yan Wang, Zebo Jiang, Jumin Huang, Hu-Dan Pan, Yue Fan, Hongmei Xu, Feng Wang, Haopeng Rui, Piu Wong, Hermi Sumatoh, Michael Fehlings, Alessandra Nardin, Paul Gavine, Longen Zhou, Yabing Cao, Liang Liu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Response to immunotherapy widely varies among cancer patients and identification of parameters associating with favourable outcome is of great interest. Here we show longitudinal monitoring of peripheral blood samples of non-small cell lung
Externí odkaz:
https://doaj.org/article/c845ab00de49468c83ac80f41f9fb0d6
Autor:
Michael Fehlings, Suchit Jhunjhunwala, Marcin Kowanetz, William E. O’Gorman, Priti S. Hegde, Hermi Sumatoh, Boon Heng Lee, Alessandra Nardin, Etienne Becht, Susan Flynn, Marcus Ballinger, Evan W. Newell, Mahesh Yadav
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background There is strong evidence that immunotherapy-mediated tumor rejection can be driven by tumor-specific CD8+ T cells reinvigorated to recognize neoantigens derived from tumor somatic mutations. Thus, the frequencies or characteristic
Externí odkaz:
https://doaj.org/article/521c2f3238b047f6a7391405547e902b
Autor:
Michael G. Fehlings, Evan W. Newell, Tony Kiat Hon Lim, Wai Yee Woo, Mohamad Farid, N. Gopalakrishna Iyer, Luo Huang, Enya H.W. Ong, Kar Perng Low, Wen-long Nei, Melvin L.K. Chua, Kai Yao, Zhong-Guo Liang, Pek Lim Chu, Haitao Wang, Ravindran Kanesvaran, Mei-Kim Ang, Daniel Shao-Weng Tan, Hermi Sumatoh, Rebecca Dent, Chee Keong Toh, Eugenia Li Ling Yeo, Dennis J.J. Poon, Khee Chee Soo, Kevin L.M. Chua, Xin Min Cheng, Alessandra Nardin, Joseph Wee
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 108:70-80
Purpose Improved antitumor responses have been observed in patients after combination radiation therapy (RT) and immune checkpoint blockade (ICB). Whether these clinical responses are linked to the host systemic immune system has not been elucidated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e88316b32753679f2e093341b80a7a3
https://doi.org/10.1016/j.ijrobp.2020.06.007
https://doi.org/10.1016/j.ijrobp.2020.06.007
Autor:
Run-Ze Li, Yue Fan, Haopeng Rui, Longen Zhou, Paul Gavine, Liang Liu, Hongmei Xu, Yabing Cao, Michael G. Fehlings, Ze-Bo Jiang, Piu Wong, Xing-Xing Fan, Alessandra Nardin, Hu-Dan Pan, Hermi Sumatoh, Elaine Leung, Yan Wang, Lily Yan Wang, Ju-Min Huang
The response to immunotherapy could be better predicted by using a wide set of biomarkers, including serum tumor markers; however, robust immune markers associated with efficacy have yet to be validated. In this study, changes in immune cell subsets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad2e68f4b7dfe4f532452ae3f1006291
https://doi.org/10.21203/rs.3.rs-863654/v1
https://doi.org/10.21203/rs.3.rs-863654/v1
Autor:
Hermi Sumatoh, Eshan U. Patel, Maria Bettinotti, Aaron A.R. Tobian, Andrew Pekosz, Hassen Kared, Shmuel Shoham, Evan W. Newell, Thomas C. Quinn, David J. Sullivan, Daniel Carbajo, Andrew D. Redd, Kirsten Littlefield, Faris Kairi, Tania S. Bonny, Alessandra Nardin, Brian Abel, Arturo Casadevall, Evan M. Bloch, Michael G. Fehlings, Oliver Laeyendecker, Sarah E. Benner
Publikováno v:
J Clin Invest
Characterization of the T cell response in individuals who recover from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical to understanding its contribution to protective immunity. A multiplexed peptide-MHC tetramer ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4789ad096aa74226198fe908ef04b10e
https://doi.org/10.1172/jci145476
https://doi.org/10.1172/jci145476
Autor:
Oliver Laeyendecker, Sarah E. Benner, Hermi Sumatoh, Aaron A.R. Tobian, Daniel Carbajo, Alessandra Nardin, Hassen Kared, Evan W. Newell, Thomas C. Quinn, Andrew Redd, Faris Kairi, Brian Abel, Tania S. Bonny, Andrew Pekosz, Evan M. Bloch
Publikováno v:
Open Forum Infectious Diseases
Background Understanding the diversity, breadth, magnitude, and functional profile of the T cell response against SARS-CoV-2 in recovered COVID-19 individuals is critical to evaluate the contribution of T cells to produce a potentially protective imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83c8215f064932a36c6ec9a6dbb8e84
Autor:
Faris Kairi, Tania S. Bonny, Hassen Kared, David J. Sullivan, Kirsten Littlefield, Michael G. Fehlings, Arturo Casadevall, Alessandra Nardin, Maria Bettinotti, Aaron A.R. Tobian, Oliver Laeyendecker, Daniel Carbajo, Sarah E. Benner, Evan M. Bloch, Andrew Pekosz, Brian Abel, Hermi Sumatoh, Andrew D. Redd, Eshan U. Patel, Shmuel Shoham, Evan W. Newell, Thomas C. Quinn
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Characterization of the T cell response in individuals who recover from SARS-CoV-2 infection is critical to understanding its contribution to protective immunity. A multiplexed peptide-MHC tetramer approach was used to screen 408 SARS-CoV-2 candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161fb47a46850e7a52383f8d420d8eb9
https://europepmc.org/articles/PMC7553170/
https://europepmc.org/articles/PMC7553170/
Autor:
Larry Lai Wei, Thomas Yau, Irene Oi-Lin Ng, Carmen Chak-Lui Wong, Jacinth Wing-Sum Cheu, Hermi Sumatoh, Vox Ting, Alessandra Nardin, Evan W. Newell, Vincent Wai-Hin Yuen, Michael G. Fehlings, David Kung-Chun Chiu, Chun-Ming Wong
Publikováno v:
Gastroenterology. 159(2)
Background & Aims Immune checkpoint inhibitors are effective in the treatment of some hepatocellular carcinomas (HCCs), but these tumors do not always respond to inhibitors of programmed cell death 1 (PDCD1, also called PD1). We investigated mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa05577e245af9c368842bc600d61dd8
https://pubmed.ncbi.nlm.nih.gov/32574623
https://pubmed.ncbi.nlm.nih.gov/32574623
Publikováno v:
Cytometry Part A. 91:48-61
The advent of mass cytometry has facilitated highly multi-parametric single-cell analysis allowing for the deep assessment of cellular diversity. While the data and analytical power of this approach are well described, associated technical and experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d4acdccfb816155df2cd568641fcaff
https://doi.org/10.1002/cyto.a.23014
https://doi.org/10.1002/cyto.a.23014
Autor:
Bjarne Bogen, Mahesh Choolani, Dedrick Kok Hong Chan, Tony Lim Kiat Hon, Charles-Antoine Dutertre, Jerry Kok Yen Chan, Florent Ginhoux, Anis Larbi, Sandrine Henri, Svetoslav Chakarov, Citra Nurfarah Zaini Mattar, Evan W. Newell, Naomi McGovern, Sofie Van Gassen, Jinmiao Chen, Simon Tavernier, Tam John Kit Chung, Michael Poidinger, Sergio Erdal Irac, Dorine Sichien, Hervé Luche, Ivy Low, Hermi Sumatoh, Sofie De Prijck, Gillian Low, Ker-Kan Tan, Bart N. Lambrecht, Even Fossum, Martin Guilliams, Yvan Saeys, Bernard Malissen, Charlotte L. Scott
Publikováno v:
Immunity, 45(3), 669-684. Cell Press
Immunity
Immunity, 2016, 45, pp.669-684. ⟨10.1016/j.immuni.2016.08.015⟩
Immunity, Elsevier, 2016, 45, pp.669-684. ⟨10.1016/j.immuni.2016.08.015⟩
IMMUNITY
Immunity
Immunity, 2016, 45, pp.669-684. ⟨10.1016/j.immuni.2016.08.015⟩
Immunity, Elsevier, 2016, 45, pp.669-684. ⟨10.1016/j.immuni.2016.08.015⟩
IMMUNITY
Summary Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic potential. Multiple DC subsets have been described, and it remains challenging to align them across tissues and species to analyze their function in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9aea8398c0f153bc3f29b3a580d5eb
https://pure.eur.nl/en/publications/d16200db-bbe4-48c9-9f16-cfe355704c51
https://pure.eur.nl/en/publications/d16200db-bbe4-48c9-9f16-cfe355704c51