Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Hermann Rapp"'
1
Akademický článek
Gene expression databases for physiologically based pharmacokinetic modeling of humans and animal species
Autor: Henrik Cordes, Hermann Rapp
Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 3, Pp 311-319 (2023)
Abstract In drug research, developing a sound understanding of the key mechanistic drivers of pharmacokinetics (PK) for new molecular entities is essential for human PK and dose predictions. Here, characterizing the absorption, distribution, metaboli
Externí odkaz: https://doaj.org/article/33a6bc3889604a2c86bcda97233026a8
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2
Akademický článek
Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood–Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery
Autor: Yunhai Cui, Ralf Lotz, Hermann Rapp, Klaus Klinder, Anneke Himstedt, Achim Sauer
Publikováno v: Pharmaceutics, Vol 11, Iss 11, p 595 (2019)
Movement of xenobiotic substances across the blood−brain barrier (BBB) is tightly regulated by various transporter proteins, especially the efflux transporters P-glycoprotein (P-gp/MDR1) and breast cancer resistance protein (BCRP). Avoiding drug ef
Externí odkaz: https://doaj.org/article/84ea435ab49f49b6880b1423e43d1294
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3
Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood–Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery
Autor: Achim Sauer, Hermann Rapp, Anneke Himstedt, Klaus Klinder, Yunhai Cui, Ralf Lotz
Publikováno v: Pharmaceutics, Vol 11, Iss 11, p 595 (2019)
Pharmaceutics
Volume 11
Issue 11
Movement of xenobiotic substances across the blood&ndash
brain barrier (BBB) is tightly regulated by various transporter proteins, especially the efflux transporters P-glycoprotein (P-gp/MDR1) and breast cancer resistance protein (BCRP). Avoidin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02fe2dc72fea11cd90d8cf87841d910
https://www.mdpi.com/1999-4923/11/11/595
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4
Quantitation of the new hypoglycaemic agent AG-EE 388 ZW in human plasma by automated high-performance liquid chromatography with electrochemical detection
Autor: Andreas Greischel, Hermann Rapp, Willy Roth, Klaus Beschke
Publikováno v: Journal of chromatography. 568(1)
A sensitive and selective high-performance liquid chromatographic assay has been developed for a new hypoglycaemic agent AG-EE 388 ZW (I) in human plasma. Plasma samples containing I were acidified with 0.2 M hydrochloric acid, directly injected into
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aedb150b8e47bc6d83b6245dd3ac928
https://pubmed.ncbi.nlm.nih.gov/1770103
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7
Sealing Problems and Solutions in the Sealing of Truck Axle Pinions and Wheels by Radial Shaft Seals
Autor: Hermann Rapp, Rolf Drucktenhengst
Publikováno v: SAE Technical Paper Series.
Problemes d'etancheite et leurs solutions dans le cas des pignons d'essieux et des roues de camions. Utilisation de joints radiaux pour arbres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d9b40c538bd415d4f24468669f8b1f6
https://doi.org/10.4271/841150
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10
Akademický článek
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