Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Hermann Ragg"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97879 (2014)
Vertebrates evolved an endothelium-lined hemostatic system and a pump-driven pressurized circulation with a finely-balanced coagulation cascade and elaborate blood pressure control over the past 500 million years. Genome analyses have identified prin
Externí odkaz:
https://doaj.org/article/41847390fbaa499bad83d60af85a51a5
Autor:
Ying Zheng, Hermann Ragg, Yunjie Wang, Haiyan Cai, Zhenquan Wei, Ruoxi Zhang, Jiawei Wu, Aiwu Zhou, Xin Huang, Lina Ma, Fei Zhang, Hudie Wei, Lingling Feng
Publikováno v:
The Journal of biological chemistry. 291(48)
Lamprey angiotensinogen (l-ANT) is a hormone carrier in the regulation of blood pressure, but it is also a heparin-dependent thrombin inhibitor in lamprey blood coagulation system. The detailed mechanisms on how angiotensin is carried by l-ANT and ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3e6f37a54b7a38fa495fc72068ba9d
https://pubmed.ncbi.nlm.nih.gov/27681598
https://pubmed.ncbi.nlm.nih.gov/27681598
Autor:
Hermann Ragg, Yunjie Wang
Publikováno v:
The Serpin Family ISBN: 9783319227108
Lampreys and hagfish are the only extant lineages of jawless fish that diverged from jawed vertebrates more than half a billion years ago. Lampreys, in particular, are regarded as a model system for the study of ancestral vertebrate-specific traits,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd623693d721396ed8789a3308e4a9c
https://doi.org/10.1007/978-3-319-22711-5_4
https://doi.org/10.1007/978-3-319-22711-5_4
Publikováno v:
Biochemical Journal. 395:449-456
Lancelets are considered to take a key position in the evolution of lineages leading to vertebrates. Herein, a serpin from the lancelet Branchiostoma lanceolatum, Bl-Spn1, was identified that inhibits the PCs (proprotein convertases) PC1/3 and furin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931105f9e62f44b1b5f2d152075ed5ed
https://doi.org/10.1042/bj20051947
https://doi.org/10.1042/bj20051947
Autor:
Christoph Böhme, Annemarie Strathmann, Eckart Grabenhorst, Harald S. Conradt, Hermann Ragg, Manfred Nimtz
Publikováno v:
European Journal of Biochemistry. 269:977-988
The structure of post-translational modifications of human heparin cofactor II isolated from human serum and from recombinant Chinese hamster ovary cells and their effects on heparin binding have been characterized. Oligosaccharide chains were found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93dc612e7e446265d852500499d13150
https://doi.org/10.1046/j.0014-2956.2001.02732.x
https://doi.org/10.1046/j.0014-2956.2001.02732.x
Autor:
Fatma Sfaxi, Nathalie Scamuffa, Fabien Calvo, Claude Lalou, Hermann Ragg, Andreas Bikfalvi, Geraldine Siegfried, Abdel-Majid Khatib, Peter Metrakos, Jia Ma
Publikováno v:
Oncotarget
Liver is the most common site of metastasis from colorectal cancers, and liver of patients with liver colorectal metastasis have abnormal levels of the proprotein convertases (PCs). These proteases are involved in the activation and/or expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a796ba7cefd9afae85e095835e3c169f
https://pubmed.ncbi.nlm.nih.gov/24961901
https://pubmed.ncbi.nlm.nih.gov/24961901
Publikováno v:
Molecular Biology and Evolution. 18:1502-1511
Phylogenetic analyses of 110 serpin protein sequences revealed clades consistent with independent phylogenetic analyses based on exon-intron structure and diagnostic amino acid sites. Trees were estimated by maximum likelihood, neighbor joining, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d85895194fa1959bab22f80dc364746
https://doi.org/10.1093/oxfordjournals.molbev.a003936
https://doi.org/10.1093/oxfordjournals.molbev.a003936
Autor:
Stefan Börner, Hermann Ragg
In several branches of the tree of life, alternative splicing of a single primary transcript may give rise to multiple serpin isoforms exhibiting different target enzyme specificities. Though the continuously increasing number of genome sequencing pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2fbe4014fd2436a9dd5d2e1d38718c
https://doi.org/10.1016/b978-0-12-385950-1.00010-9
https://doi.org/10.1016/b978-0-12-385950-1.00010-9
Autor:
Hermann Ragg, Yunjie Wang
Angiotensinogen is well known as source protein for a group of potent vasoactive hormones, however, a discrete biochemical activity of the angiotensinogen body is not known. Here we investigated angiotensinogen from the lamprey Lampetra fluviatilis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467fb181ff098559229e207021a36716
https://doi.org/10.1016/j.febslet.2011.06.021
https://doi.org/10.1016/j.febslet.2011.06.021
Autor:
Hermann Ragg
Publikováno v:
Cellular and molecular life sciences : CMLS. 68(2)
The genesis of the exon-intron patterns of eukaryotic genes persists as one of the most enigmatic questions in molecular genetics. In particular, the origin and mechanisms responsible for creation of spliceosomal introns have remained controversial.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4183529a335777e280d23baa010fd0a
https://pubmed.ncbi.nlm.nih.gov/20853128
https://pubmed.ncbi.nlm.nih.gov/20853128