Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Hermann M, Schätzl"'
Autor:
Sabine Gilch, Hermann M. Schätzl
Publikováno v:
Cell and Tissue Research. 392:1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a50da1e6383abbd32b1f7b4503ccc51
https://doi.org/10.1007/s00441-023-03760-y
https://doi.org/10.1007/s00441-023-03760-y
Autor:
Andrea Fehlinger, Hanna Wolf, André Hossinger, Yvonne Duernberger, Catharina Pleschka, Katrin Riemschoss, Shu Liu, Romina Bester, Lydia Paulsen, Suzette A. Priola, Martin H. Groschup, Hermann M. Schätzl, Ina M. Vorberg
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Prions are unconventional agents composed of misfolded prion protein that cause fatal neurodegenerative diseases in mammals. Prion strains induce specific neuropathological changes in selected brain areas. The mechanism of strain-specific ce
Externí odkaz:
https://doaj.org/article/13fe002f36ce4b6588374aa799d3ba3e
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1305 (2020)
Many devastating neurodegenerative diseases are driven by the misfolding of normal proteins into a pathogenic abnormal conformation. Examples of such protein misfolding diseases include Alzheimer’s disease, Parkinson’s disease, Huntington’s dis
Externí odkaz:
https://doaj.org/article/41efe08642db44ce99d5a48c36ff17d6
Autor:
Keita Arai, Ayumi Oguma, Miki Watanabe-Matsui, Kenta Teruya, Yuji Sakasegawa, Keiko Nishizawa, Sabine Gilch, Sara Iwabuchi, Katsumi Doh-ura, Hermann M. Schätzl
Publikováno v:
Biochemical and Biophysical Research Communications. 560:105-111
Anti-prion effects of cellulose ether (CE) are reported in rodents, but the molecular mechanism is fully unknown. Here, we investigated the genetic background of CE effectiveness by proteomic and genetic analysis in mice. Proteomic analysis in the tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea04cc86735f8eb92b9e6f932392386
https://doi.org/10.1016/j.bbrc.2021.04.116
https://doi.org/10.1016/j.bbrc.2021.04.116
Autor:
Melia T DeVivo, David R Edmunds, Matthew J Kauffman, Brant A Schumaker, Justin Binfet, Terry J Kreeger, Bryan J Richards, Hermann M Schätzl, Todd E Cornish
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186512 (2017)
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus nelsoni), and moose (Alces alces shirasi) in No
Externí odkaz:
https://doaj.org/article/0f238ec68b494749ae126d2804d0f260
Autor:
Basant A. Abdulrahman, Waqas Tahir, Simrika Thapa, Rupali Walia, Dalia H. A. Abdelaziz, Hermann M. Schätzl
Publikováno v:
The Journal of Biological Chemistry
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrPC) into the pathological isoform PrPSc. Elucidating the molecular and cellular mechanisms underlying prion pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed81a33d5f7d251045568d6c1825491
https://doi.org/10.1074/jbc.ra120.012596
https://doi.org/10.1074/jbc.ra120.012596
Autor:
Basant Abdulrahman, Dalia H. A. Abdelaziz, Lauren Vankuppeveld, Hermann M. Schätzl, Simrika Thapa
Publikováno v:
Biochemical and Biophysical Research Communications. 523:423-428
Prion diseases are fatal infectious neurodegenerative disorders in human and animals that are caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform PrPSc. No effective treatment is available for prion diseases. Metform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80854e8f73046228136223dc3a337fb
https://doi.org/10.1016/j.bbrc.2019.12.074
https://doi.org/10.1016/j.bbrc.2019.12.074
Publikováno v:
Molecular Neurobiology. 57:2206-2219
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform PrPSc. These diseases have the potential to transmit within or between species,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ac072f9500e172ecea7eb8dfe26c5c
https://doi.org/10.1007/s12035-020-01880-y
https://doi.org/10.1007/s12035-020-01880-y
Autor:
Katsumi Doh-ura, Maria Immaculata Arifin, Preetha Gopalakrishnan, Samia Hannaoui, Sheng Chun Chang, Sabine Gilch, Jie Yu, Hermann M. Schätzl
Publikováno v:
Journal of Neurochemistry
Chronic wasting disease (CWD) is a prion disease of free‐ranging and farmed cervids that is highly contagious because of extensive prion shedding and prion persistence in the environment. Previously, cellulose ether compounds (CEs) have been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca1703b5df129154c410abb47f950d6
https://doi.org/10.1111/jnc.14877
https://doi.org/10.1111/jnc.14877
Autor:
Keiko Nishizawa, Sabine Gilch, Katsumi Doh-ura, Ayumi Oguma, Hermann M. Schätzl, Kenta Teruya, Yuji Sakasegawa
Publikováno v:
Journal of Pharmaceutical Sciences. 108:2814-2820
Prion accumulation in the brain and lymphoreticular system causes fatal neurodegenerative diseases. Our previous study revealed that cellulose ethers (CE) have anti-prion activities in vivo and in prion-infected cells when administered at high doses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922bfe0f2115fa1c3dca4cdb55d36e66
https://doi.org/10.1016/j.xphs.2019.03.025
https://doi.org/10.1016/j.xphs.2019.03.025