Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hermann Poschenrieder"'
Autor:
Christa E. Müller, Hans-Dietrich Stachel, Raghuram Rao Akkinepally, Hermann Poschenrieder, Anke C. Schiedel, Meryem Köse, Alexander Andreas Bauer, Joachim C. Burbiel
Publikováno v:
Bioorganicmedicinal chemistry. 24(21)
Adenosine kinase (AdK) is a key player in controlling intra- and extracellular concentrations of the signaling molecule adenosine. Extensive evidence points to an important role of AdK in several diseases, and suggests that AdK inhibition might be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228429293e080d845822edbf2d1a9ba0
https://pubmed.ncbi.nlm.nih.gov/27595538
https://pubmed.ncbi.nlm.nih.gov/27595538
Publikováno v:
Zeitschrift für Naturforschung B. 64:427-433
The triethyloxonium tetrafluoroborate/1,2-dimethoxyethane (TEO/DME) mixture is a versatile and cheap substitute for trimethyloxonium tetrafluoroborate in O-methylations of pyrrolin-2-ones, quinolones, acridones, and 1-oxo-β -carbolines. Undesired O-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcd99d3df3db8cfd3ab3748a10040fc
https://doi.org/10.1515/znb-2009-0412
https://doi.org/10.1515/znb-2009-0412
Autor:
Hans-Dietrich Stachel, Eduard Eckl, Sabine Jax, Hermann Poschenrieder, Kurt Polborn, Peter Mayer
Publikováno v:
Helvetica Chimica Acta. 89:971-982
Ozonations of alkoxy- and (acyloxy)-substituted alkylidene-lactams 1 and 5 or of the alkylidene-sultams 9 and 10 proceeded by regioselective cleavage of the exocyclic CC bonds (Schemes 1 and 2). These bonds are part of an enamide system and, therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7871377f7abefc398def499f1e1e4256
https://doi.org/10.1002/hlca.200690101
https://doi.org/10.1002/hlca.200690101
Publikováno v:
European Journal of Medicinal Chemistry. 40:391-400
A series of oximes, deriving from 2-arylidene-pyrroline-3,4-diones (7, 8, 22, 23) has been prepared. The presence of tautomers in their solutions has been established by spectroscopic means. The compounds reacted with diazomethane chiefly by N-methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e8219882bd8d25da48b75c7a14d742
https://doi.org/10.1016/j.ejmech.2004.11.010
https://doi.org/10.1016/j.ejmech.2004.11.010
Autor:
Wolfgang Weigand, Hans-Dietrich Stachel, Andreas Windt, Hermann Poschenrieder, Elisabeth Immerz-Winkler, Ralf Wünsch, Norbert Drescher
Publikováno v:
Helvetica Chimica Acta. 86:2471-2480
The title compounds were prepared starting from the dihydropyrrolones 4–6. Nucleophilic displacement and ring closure yielded the 1H-pyrrolo[3,2-c]isothiazol-5(4H)-ones 8 and 10. The fused systems formed salts with strong acids and electrophiles (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fedd0cab4c2c1a437f626bf9f8dbeb80
https://doi.org/10.1002/hlca.200390200
https://doi.org/10.1002/hlca.200390200
Publikováno v:
Journal of Heterocyclic Chemistry. 40:61-69
Ozonolysis of the pyrrolidinediones 4 afforded the pyrrolidinetriones 5, which in the presence of Lewis acids were converted into maleimide 6. Analogously, ozonolysis of the pyrrolidinones 7 gave the pyrrolidinediones 8, which were converted into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ad25703ec75a87c45451b8c3967aa4
https://doi.org/10.1002/jhet.5570400108
https://doi.org/10.1002/jhet.5570400108
Publikováno v:
Archiv der Pharmazie. 333:211-216
A series of piperidine-2,3,5-triones (azagrevelfins) has been prepared. A new synthesis has been introduced using the rearrangement of spiroepoxides in the presence of triethyloxonium tetrafluoroborate. The binding affinity toward the N-methyl-D-aspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163dda40971608c1f565a5ae443236c8
https://doi.org/10.1002/1521-4184(20007)333:7<211::aid-ardp211>3.0.co
https://doi.org/10.1002/1521-4184(20007)333:7<211::aid-ardp211>3.0.co
Publikováno v:
Journal of Heterocyclic Chemistry. 37:839-846
The 4-hydroxypyridones 7 and 3-hydroxypyridones 8/9 (azagrevellins) were prepared by reaction of the pyrrolidinetrione 4 and diazoalkanes. The ring enlargement proceeded by anionotropic [1,2]-rearrangement introducing carbon between C-3 and C-4 or, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e62fa0ef11983ce12840485c4c44760d
https://doi.org/10.1002/jhet.5570370428
https://doi.org/10.1002/jhet.5570370428
Publikováno v:
Archiv der Pharmazie. 332:309-316
A series of oximes deriving from 5-arylidene-pyrrolidine-2,3,4-triones and pyridine-2,3,4-triones has been prepared. The presence of the tautomeric nitrosoenol was proven in solutions of alpha-ketooxime 7a. The binding affinity of the new oximes towa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66a7131288ccb4b01b99eee385c8856
https://doi.org/10.1002/(sici)1521-4184(19999)332:9<309::aid-ardp309>3.0.co
https://doi.org/10.1002/(sici)1521-4184(19999)332:9<309::aid-ardp309>3.0.co
Publikováno v:
Archiv der Pharmazie. 331:389-394
A series of new 5-arylidene 3-aryl-pyrrolidine-2,4-diones has been prepared. Their binding affinity toward the N-methyl-D-aspartate (glycine site) receptor has been measured as a basis for more detailed structure-activity relationship studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::300aa7b9f99074f9cf1f1e365fc4596a
https://doi.org/10.1002/(sici)1521-4184(199812)331:12<389::aid-ardp389>3.0.co
https://doi.org/10.1002/(sici)1521-4184(199812)331:12<389::aid-ardp389>3.0.co