Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Herman W Favoreel"'
Autor:
Jonas L Delva, Cliff Van Waesberghe, Barbara G Klupp, Thomas C Mettenleiter, Herman W Favoreel
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010117 (2021)
Plasmacytoid dendritic cells (pDC) are important innate immune cells during the onset of viral infections as they are specialized in the production of massive amounts of antiviral type I interferon (IFN). Alphaherpesviruses such as herpes simplex vir
Externí odkaz:
https://doaj.org/article/0d1ceb4dee1a43358afdc2d1d5a78d7c
Autor:
Sarah Glorieux, Claus Bachert, Herman W Favoreel, Annelies P Vandekerckhove, Lennert Steukers, Anamaria Rekecki, Wim Van den Broeck, Joline Goossens, Siska Croubels, Reginald F Clayton, Hans J Nauwynck
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22160 (2011)
BackgroundHerpes simplex virus infections are highly prevalent in humans. However, the current therapeutics suffer important drawbacks such as limited results in neonates, increasing occurrence of resistance and impeded treatment of stromal infection
Externí odkaz:
https://doaj.org/article/45c9e670fca84478826f38a952d43c81
Autor:
Peter L Delputte, Hanne Van Gorp, Herman W Favoreel, Inge Hoebeke, Iris Delrue, Hannah Dewerchin, Frank Verdonck, Bruno Verhasselt, Eric Cox, Hans J Nauwynck
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16827 (2011)
Sialoadhesin is exclusively expressed on specific subpopulations of macrophages. Since sialoadhesin-positive macrophages are involved in inflammatory autoimmune diseases, such as multiple sclerosis, and potentially in the generation of immune respons
Externí odkaz:
https://doaj.org/article/b6f24dbe68cc4aeda6019d036df982fa
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Several alphaherpesviruses, including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), establish lifelong latency in neurons of the trigeminal ganglion (TG). Although it is thought that efficient establishment of alphaherpesvirus latency
Externí odkaz:
https://doaj.org/article/67dd2e062f1c4537a97818cd31adc927
Autor:
Leen Hermans, Sofie Denaeghel, Robert J. J. Jansens, Steffi De Pelsmaeker, Filip Van Nieuwerburgh, Dieter Deforce, Everardo Hegewisch-Solloa, Emily M. Mace, Eric Cox, Bert Devriendt, Herman W. Favoreel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Liver-resident NK (lrNK) cells have been studied in humans as well as in mice. Unfortunately, important differences have been observed between murine and human lrNK cells, complicating the extrapolation of data obtained in mice to man. We previously
Externí odkaz:
https://doaj.org/article/249d3b1fcb854cf5aeb496ceddaf121e
Autor:
Nicolás Romero, Alexander Tishchenko, Ruth Verhamme, Shelly M. Wuerzberger-Davis, Cliff Van Waesberghe, Hans J. Nauwynck, Shigeki Miyamoto, Herman W. Favoreel
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Alphaherpesvirus infection is associated with attenuation of different aspects of the host innate immune response that is elicited to confine primary infections at the mucosal epithelia. Here, we report that infection of epithelial cells wit
Externí odkaz:
https://doaj.org/article/6d610267a4164015bad98e8821b2a57e
Autor:
Robert J.J. Jansens, Anthony Olarerin-George, Ruth Verhamme, Aashiq Mirza, Samie Jaffrey, Herman W. Favoreel
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107310- (2023)
Summary: The mechanisms by which viruses regulate host mRNAs during infection are still poorly understood. Several host transcripts that encode proteins that contribute to the anti-viral response contain the N6-methyladenosine nucleotide (m6A). In th
Externí odkaz:
https://doaj.org/article/e57474c9300949e4b9427ebb94b1dd9e
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs)
Externí odkaz:
https://doaj.org/article/dced218e8f7e4972ac5a0d5215969343
Publikováno v:
Methods and Protocols, Vol 6, Iss 3, p 55 (2023)
Protein phosphorylation is a ubiquitous post-translational modification that regulates a plethora of intracellular processes, making its analysis crucial for understanding intracellular dynamics. The commonly used methods, such as radioactive labelin
Externí odkaz:
https://doaj.org/article/e448a3e48f354ab5b96caa760345d590
Autor:
Leen Hermans, Steffi De Pelsmaeker, Sofie Denaeghel, Eric Cox, Herman W. Favoreel, Bert Devriendt
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Beta-glucans are naturally occurring polysaccharides present in cell walls of fungi, yeast, bacteria, cereals, seaweed, and algae. These microbe-associated molecular patterns (MAMPs) possess immunomodulatory properties. In human, it has been suggeste
Externí odkaz:
https://doaj.org/article/de29fc980664424990b67f6bfbfa9030