Výsledky vyhledávání - "Herman S.Y. Liu"

4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4

Autor: Jian Hou, J. C. W. Chan, Wai Shan Wong, Suk Hang Cheng, Kin-Mang Lau, Margaret H.L. Ng, Hua Jiang, Raymond W. Chu, Natalie P. H. Chan, Ho Keung Ng, Kwok Wai Lo, Angela B.Y. Hui, Herman S.Y. Liu

Publikováno v: Blood. 109:2089-2099

In this study, we have elucidated the chromosomal imbalances in the multistep pathogenesis and delineated several critical tumor suppressor gene (TSG) loci in multiple myeloma (MM). By using comparative genomic hybridization, allelotyping, and multic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f068d4bd2139c42f4233ec48deaf652b
https://doi.org/10.1182/blood-2006-04-018770

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Next-generation sequencing with a myeloid gene panel in core-binding factor AML showed KIT activation loop and TET2 mutations predictive of outcome

Publikováno v: Blood Cancer Journal

Clinical outcome and mutations of 96 core-binding factor acute myeloid leukemia (AML) patients 18–60 years old were examined. Complete remission (CR) after induction was 94.6%. There was no significant difference in CR, leukemia-free-survival (LFS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa97bc75b5ffb0e54703c903b1527eb4
https://doi.org/10.1038/bcj.2016.51

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The Use of Clofarabine and Cytarabine Combination (CLARA) As Salvage Therapy for Relapsed and/or Refractory Acute Myeloid Leukemia (AML)

Autor: Harold K. K. Lee, Eric Tse, Yok-Lam Kwong, Joycelyn P Y Sim, Herman S.Y. Liu, Anskar Y.H. Leung, Bonnie Kho, Sze-Fai Yip

Publikováno v: Blood. 120:1518-1518

Abstract 1518 Patients with relapsed and/or refractory acute myeloid leukemia (AML) have a very dismal outcome and treatments are largely unsatisfactory. Salvage therapy is often limited by drug resistance and organ toxicities in patients who have al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5572d6cf2129ea84b9e38ac35e01852b
https://doi.org/10.1182/blood.v120.21.1518.1518

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