Zobrazeno 1 - 10
of 673
pro vyhledávání: '"Herman S, Overkleeft"'
Autor:
Melissa Thaler, Tim P. Ofman, Ken Kok, Jurriaan J. A. Heming, Elisha Moran, Isabelle Pickles, Anouk A. Leijs, Adrianus M. C. H. van den Nieuwendijk, Richard J. B. H. N. van den Berg, Gijs Ruijgrok, Zachary Armstrong, Clarisse Salgado-Benvindo, Dennis K. Ninaber, Eric J. Snijder, Constant A. A. van Boeckel, Marta Artola, Gideon J. Davies, Herman S. Overkleeft, Martijn J. van Hemert
Publikováno v:
ACS Central Science, Vol 10, Iss 8, Pp 1594-1608 (2024)
Externí odkaz:
https://doaj.org/article/dd42ac5e444a4e7ba47c0548b472ccb4
Autor:
Conor J. R. Scott, Nicholas G. S. McGregor, Daniel R. Leadbeater, Nicola C. Oates, Janina Hoßbach, Amira Abood, Alexander Setchfield, Adam Dowle, Herman S. Overkleeft, Gideon J. Davies, Neil C. Bruce
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Parascedosporium putredinis NO1 is a plant biomass-degrading ascomycete with a propensity to target the most recalcitrant components of lignocellulose. Here we applied proteomics and activity-based protein profiling (ABPP) to investigate the
Externí odkaz:
https://doaj.org/article/5af28a9d52c443db935cb81de8b8bc98
Autor:
Nicholas G. S. McGregor, Casper de Boer, Quentin P. O. Foucart, Thomas Beenakker, Wendy A. Offen, Jeroen D. C. Codée, Lianne I. Willems, Herman S. Overkleeft, Gideon J. Davies
Publikováno v:
ACS Central Science, Vol 9, Iss 12, Pp 2306-2314 (2023)
Externí odkaz:
https://doaj.org/article/0ab70068664a46b0b310b3eed566d8f6
Autor:
Christian Schmerling, Leonard Sewald, Geronimo Heilmann, Frederick Witfeld, Dominik Begerow, Kenneth Jensen, Christopher Bräsen, Farnusch Kaschani, Herman S. Overkleeft, Bettina Siebers, Markus Kaiser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Activity-based protein profiling is used to screen lignocellulose-degrading enzymes from the white rot fungus Phanerochaete chrysosporium to identify those specifically active in the presence of wood substrate.
Externí odkaz:
https://doaj.org/article/ba41cd87d0ad4fcda143d7d537ab4246
Autor:
Alex van der Ham, Xue Liu, Dario Calvani, Adéla Melcrová, Melania Kozdra, Francesco Buda, Herman S. Overkleeft, Wouter H. Roos, Dmitri V. Filippov, Grégory F. Schneider
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Molecularly thin films are important in material sciences but their use in a wide range of applications requires control over their chemical functionalities, which is difficult to achieve. Here, the authors use decacyclene to form such freestanding a
Externí odkaz:
https://doaj.org/article/46885119125844f5b59529265f89e133
Autor:
Xiang Zhou, Andrej Besse, Jessica Peter, Maximilian Johannes Steinhardt, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Xianghui Xiao, Hannah Hornburger, Larissa Haertle, Max Mendez Lopez, Umair Munawar, Angela Riedel, Seungbin Han, Elmer Maurits, Herman S. Overkleeft, Bogdan Florea, Hermann Einsele, K. Martin Kortüm, Christoph Driessen, Lenka Besse, Leo Rasche
Publikováno v:
Haematologica, Vol 108, Iss 6 (2023)
Optimal carfilzomib dosing is a matter of debate. We analyzed the inhibition profiles of proteolytic proteasome subunits β5, β2 and β1 after low-dose (20/27 mg/m2) versus high-dose (≥36 mg/m2) carfilzomib in 103 pairs of peripheral blood mononuc
Externí odkaz:
https://doaj.org/article/145781d6796c4523aa127a2cf8216c97
Autor:
Jeroen van Smeden, Hanin Al-Khakany, Yichen Wang, Dani Visscher, Nicole Stephens, Samira Absalah, Herman S. Overkleeft, Johannes M.F.G. Aerts, Alain Hovnanian, Joke A. Bouwstra
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 6, Pp 859-869 (2020)
Individuals with Netherton syndrome (NTS) have increased serine protease activity, which strongly impacts the barrier function of the skin epidermis and leads to skin inflammation. Here, we investigated how serine protease activity in NTS correlates
Externí odkaz:
https://doaj.org/article/c986b4ebf6c140799096c6d0fac06e3a
Autor:
Tom van der Wel, Riet Hilhorst, Hans den Dulk, Tim van den Hooven, Nienke M. Prins, Joost A. P. M. Wijnakker, Bogdan I. Florea, Eelke B. Lenselink, Gerard J. P. van Westen, Rob Ruijtenbeek, Herman S. Overkleeft, Allard Kaptein, Tjeerd Barf, Mario van der Stelt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Chemical tools to monitor drug-target engagement of endogenous enzymes are essential for preclinical target validation. Here, the authors present a chemical genetics strategy to study target engagement of endogenous kinases, achieving specific labeli
Externí odkaz:
https://doaj.org/article/749ac4b664044b4d9100599885c8e063
Autor:
Thomas Klaus, Sabrina Ninck, Andreas Albersmeier, Tobias Busche, Daniel Wibberg, Jianbing Jiang, Alexander G. Elcheninov, Kseniya S. Zayulina, Farnusch Kaschani, Christopher Bräsen, Herman S. Overkleeft, Jörn Kalinowski, Ilya V. Kublanov, Markus Kaiser, Bettina Siebers
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Activity-based protein profiling (ABPP) has so far scarcely been applied in Archaea in general and, especially, in extremophilic organisms. We herein isolated a novel Thermococcus strain designated sp. strain 2319x1E derived from the same enrichment
Externí odkaz:
https://doaj.org/article/891850e2bab242aabf113e094d046fa4
Autor:
Yongzhen Zhang, Liming Wang, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Pseudomonas aeruginosa, a pathogenic Gram-negative bacterium for which currently antibiotic resistance is posing a significant problem and for which no vaccines are available, protects itself by the formation of a biofilm. The Pel polysaccharide, a c
Externí odkaz:
https://doaj.org/article/b28a7ef3705240a6953af93c23630ccc