Výsledky vyhledávání - "Herman K Gold"

Differential Healing After Sirolimus, Paclitaxel, and Bare Metal Stent Placement in Combination With Peroxisome Proliferator-Activator Receptor γ Agonists

Autor: Aloke V. Finn, Tucker Ezell, Chitra Raghunathan, Talina Davis, Frank D. Kolodgie, Michael J. Eppihimer, Xin Xu, Scott Lajoie, Gaku Nakazawa, Herman K. Gold, Michael C. John, Renu Virmani, Vinit Karmali, Rohini Polavarapu, Eduardo Acampado, Qi Cheng

Publikováno v: Circulation Research. 105:1003-1012

Rationale: Sirolimus-eluting coronary stents (SESs) and paclitaxel-eluting coronary stents (PESs) are used to reduce restenosis but have different sites of action. The molecular targets of sirolimus overlap with those of the peroxisome proliferator-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c51e45a39601a8792145df3665301d6
https://doi.org/10.1161/circresaha.109.200519

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Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis

Autor: Aloke V. Finn, Farouc A. Jaffer, Ralph Weissleder, Herman K. Gold, Vasilis Ntziachristos, Peter Libby, Elena Aikawa, Michael C. John, Claudio Vinegoni

Publikováno v: Circulation. 118:1802-1809

Background— To enable intravascular detection of inflammation in atherosclerosis, we developed a near-infrared fluorescence (NIRF) catheter-based strategy to sense cysteine protease activity during vascular catheterization. Methods and Results— T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4be77cce4fed809e477ef42a8746138
https://doi.org/10.1161/circulationaha.108.785881

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Differential Healing Responses in Polymer- and Nonpolymer-Based Sirolimus-Eluting Stents

Autor: Michael C. John, Albert Schömig, Frank D. Kolodgie, Herman K. Gold, Renu Virmani, Johanna Crimins, Scott Lajoie, Rainer Wessely, Michael Joner, Aloke V. Finn, Adnan Kastrati, Mayu Uchihashi

Publikováno v: JACC: Cardiovascular Interventions. 1:535-544

Objectives We compared the healing and inflammatory responses of polymer-free bare-metal stents (BMS), polymer-free sirolimus-eluting stents (SES) and polymer-free sirolimus-eluting stents plus estradiol (SES+ED) to Cypher drug-eluting stents (CDES)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86716eb6ac31aacb4f9cfc2a269deb9
https://doi.org/10.1016/j.jcin.2008.08.004

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Delayed Arterial Healing and Increased Late Stent Thrombosis at Culprit Sites After Drug-Eluting Stent Placement for Acute Myocardial Infarction Patients

Autor: Allen P. Burke, Aloke V. Finn, Robert Kutys, Michael Joner, Elena Ladich, Erik Mont, Frank D. Kolodgie, Gaku Nakazawa, Herman K. Gold, Renu Virmani

Publikováno v: Circulation. 118:1138-1145

Background— The long-term safety of drug-eluting stents (DES) for acute myocardial infarction (AMI) remains uncertain. Using autopsy data, we evaluated the pathological responses of the stented segment in patients treated with DES for AMI and compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85aaeb8103a15c106675a5a91ebfaed5
https://doi.org/10.1161/circulationaha.107.762047

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Comprehensive Assessment of Myocardial Perfusion Defects, Regional Wall Motion, and Left Ventricular Function by Using 64-Section Multidetector CT

Autor: Ik-Kyung Jang, Cesar Higa Nomura, Tsunehiro Yasuda, Udo Hoffmann, Javed Butler, Ricardo C. Cury, Koen Nieman, Maros Ferencik, Thomas J. Brady, Michael D. Shapiro, Suhny Abbara, Davinder S. Jassal, Herman K. Gold

Publikováno v: Radiology. 248:466-475

To evaluate the accuracy of 64-section multidetector computed tomography (CT) for the assessment of perfusion defects (PDs), regional wall motion (RWM), and global left ventricular (LV) function.All myocardial infarction (MI) patients signed informed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacce890b9ba3a7ad9fb393732d85e1b
https://doi.org/10.1148/radiol.2482071478

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Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization

Autor: Aloke V. Finn, Rakesh K. Jain, Herman K. Gold, Frank D. Kolodgie, Renu Virmani

Publikováno v: Nature Clinical Practice Cardiovascular Medicine. 4:491-502

Angiogenesis within human atherosclerotic plaques has an important role in plaque progression as immature blood vessels leak red blood cells and inflammatory mediators into the plaque center. Accumulation of free cholesterol from red blood cell membr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4577b41f052841a7ed20dd59b13f410
https://doi.org/10.1038/ncpcardio0979

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Utility of Cardiovascular Magnetic Resonance to Predict Left Ventricular Recovery After Primary Percutaneous Coronary Intervention for Patients Presenting With Acute ST-Segment Elevation Myocardial Infarction

Autor: Michael D, Shapiro, Koen, Nieman, Khurram, Nasir, Cesar H, Nomura, Ammar, Sarwar, Maros, Ferencik, Suhny, Abbara, Udo, Hoffmann, Udo, Hoffman, Herman K, Gold, Ik-Kyung, Jang, Thomas J, Brady, Ricardo C, Cury

Publikováno v: The American Journal of Cardiology. 100:211-216

Cardiac magnetic resonance (CMR) has been shown to predict left ventricular (LV) recovery in patients after acute ST-segment elevation myocardial infarction. The purpose of this investigation was to determine the relative values of infarct transmural

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f4204d378fdbe4178fab9a9a118273
https://doi.org/10.1016/j.amjcard.2007.02.079

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Vascular Responses to Drug Eluting Stents

Autor: Michael Joner, Herman K. Gold, Renu Virmani, Gaku Nakazawa, Erik Mont, Aloke V. Finn, Frank D. Kolodgie

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 27:1500-1510

Polymer-based sirolimus- (Cypher) and paclitaxel-eluting (Taxus) drug eluting stents have become the treatment of choice for patients with symptomatic coronary artery disease undergoing percutaneous coronary intervention (PCI). Although these stents

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e596963d276f1cc253c262d2427f94
https://doi.org/10.1161/atvbaha.107.144220

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Pioglitazone Inhibits In-Stent Restenosis in Atherosclerotic Rabbits by Targeting Transforming Growth Factor-β and MCP-1

Autor: Andrew Farb, Herman K. Gold, Allen P. Burke, Aloke V. Finn, Renu Virmani, Wendy Creighton, Frank D. Kolodgie, Qi Cheng, Michael Joner, Kristi Skorija, Eduardo Acampado

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 27:182-189

Objective— Although emerging data from preclinical and clinical studies suggests a reduction of in-stent restenosis with peroxisome proliferator-activated receptor (PPAR)-γ agonists, the reduction of neointimal growth via anti-inflammatory mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaefcbc6238285def7715eb462c7082
https://doi.org/10.1161/01.atv.0000251021.28725.e8

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Pathology of Drug-Eluting Stents in Humans

Autor: Herman K. Gold, Robert Kutys, Renu Virmani, Erik Mont, Aloke V. Finn, Frank D. Kolodgie, Michael Joner, Kristi Skorija, Andrew Farb, Elena Ladich

Publikováno v: Journal of the American College of Cardiology. 48:193-202

Objectives This study examined human drug-eluting stents (DES) to determine the long-term effects of these stents on coronary arterial healing and identified mechanisms underlying late stent thrombosis (LST). Background Although DES reduce the need f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69746efb66f91908fc3037e595b93080
https://doi.org/10.1016/j.jacc.2006.03.042

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