Výsledky vyhledávání - "Herman H Odens"

Novel one-pot synthesis of 2-thio-substituted-3-H-phenothiazin-3-ones driven by oxidation with sodium periodate

Autor: Herman H Odens Jr., Jae Y You, Alexandria D Gallimore, Preston H Palm, Cameron W Davis, Josue M Bahena, Jeffrey S Moser, Mackenzie E Smith, Herman H Odens

A series of novel 2-thio-substituted-3H-phenothiazin-3-ones (6h-l) was effectively synthesized in one pot after optimization of the four-step synthesis. Treatment of a 2-alkylthio-1,4-benzoquinone (3a-l) made in situ and condensed with 1,2-aminothiop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c6a89bca35bb0ef9790dd264be16af7
https://doi.org/10.3762/bxiv.2022.36.v1

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Role of Citrullinated Collagen in Autoimmune Arthritis

Autor: Linda K. Myers, Ying-Xin Ouyang, Jay R. Patel, Herman H. Odens, Virginia Woo-Rasberry, Jeoungeun Park, Ae-Kyung Yi, Edward F. Rosloniec, David D. Brand, John M. Stuart, Andrew H. Kang

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9833

Citrullination of proteins plays an important role in protein function and it has recently become clear that citrullinated proteins play a role in immune responses. In this study we examined how citrullinated collagen, an extracellular matrix protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a6d452c104d758d70d71bbcd26f9fd

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Intramolecular cyclization reactions of unsaturated amino Fischer chromium carbenes forming indoles and quinolines

Autor: Than T Mai, Mark D Meritt, Paula C Jones, Tiara N Kouadio, H John Caprara, Lucinda R. Austin, Björn C.G. Söderberg, E. Scott Helton, Tan H Ngi, Timothy L Shrout, Brian R Hearn, James A. Shriver, Herman H Odens, Seth H Cooper, Rachel Baswell

Publikováno v: Tetrahedron. 59:8775-8791

A thermally induced intramolecular annulation reaction of N-(2-alkenylphenyl)amino substituted Fischer chromium carbenes has been extensively examined. The carbene complexes were prepared in moderate to good yields by reaction of 2-aminostyrenes with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5df440d1dcf110a993515b1318438c78
https://doi.org/10.1016/j.tet.2003.09.028

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Inhibition of the thioesterase activity of human fatty acid synthase by 1,4- and 9,10-diones

Autor: Laura A. Watts, Todd Lowther, Jeffrey Daniel Schmitt, Steven J. Kridel, Lauren Filipponi, Herman H Odens

Publikováno v: Chemicalpharmaceutical bulletin. 62(9)

Fatty acid synthase (FASN) is the enzyme that synthesizes fatty acids de novo in human cells. Although FASN is generally expressed at low levels in most normal tissues, its expression is highly upregulated in many cancers. Consistent with this notion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de748e859038b5bce651781e30481f0b
https://pubmed.ncbi.nlm.nih.gov/25177021

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Rubber Chemicals Derived from Conjugate Addition. I. Syntheses of Novel 2-Thio-5-Amino Substituted Benzoquinones

Autor: Herman H. Odens, Otto W. Maender, Charles J. Rostek, Alan R. Katritzky, Michael V. Voronkov

Publikováno v: Rubber Chemistry and Technology. 74:915-925

Alkylthio-substituted benzoquinones were prepared from benzoquinone and mercaptans in 50–94% yields via NaIO4 oxidation of the intermediate hydroquinones. Subsequent addition of primary and secondary amines, in the presence of air as an oxidizing a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::574d0847c025faad5c692b28c0b0ee6f
https://doi.org/10.5254/1.3547661

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Rubber Chemicals Derived from Conjugate Addition. II. Synthesis of a Novel Class of Benzoquinone Diimines

Autor: Michael V. Voronkov, Charles J. Rostek, Herman H. Odens, Otto W. Maender, Alan R. Katritzky

Publikováno v: Rubber Chemistry and Technology. 74:927-945

Various 2-alkylthio-5-amino- and 2,5-diamino-1,4-phenylenediamines were prepared by treatment of N-(1,3-dimethylbutyl)- N′-phenyl-1,4-quinonediimine with thiols and amines using air as an oxidizing agent. Key 2-alkylthio-1, 4-benzoquinone diimines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a9ffa3f88da886853732907595285ae
https://doi.org/10.5254/1.3547662

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Photolytic Reaction of Hydroxy Fischer Carbene Complexes: Synthesis of α-Hydroxy Esters

Autor: Björn C.G. Söderberg, Herman H. Odens

Publikováno v: Organometallics. 15:5080-5084

Photolytic reaction of in situ generated pentacarbonyl(1-hydroxyalkylidene)chromium complexes in the presence of an alcohol, under 6 atm of carbon monoxide, affords α-hydroxy-substituted esters in low to moderate yield. Acetals, formed via thermal d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae67acb7908f30428d2f5c46b2ddac7c
https://doi.org/10.1021/om960530x

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ChemInform Abstract: Novel Syntheses of 2,3-Dihydro-1,5-benzothiazepin-4(5H)-ones and 2H-1,4-Benzothiazin-3(4H)-ones

Autor: Suoming Zhang, Alan R. Katritzky, Charles J. Rostek, Herman H. Odens, Otto W. Maender

Publikováno v: ChemInform. 33

Nucleophilic additions of α-mercaptoalkanoate esters and β-mercaptoalkanoate acids to benzoquinone diimines, followed by cyclization with trifluoroacetic acid or 1,3-dicyclohexylcarbodiimide (DCC), provide novel, high-yielding syntheses of 2H-1,4-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2d97b5bff6b272eebeae1010c1ce35d
https://doi.org/10.1002/chin.200211152

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