Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Heribert Arnhof"'
Autor:
Joachim Bröker, Alex G. Waterson, Chris Smethurst, Dirk Kessler, Jark Böttcher, Moriz Mayer, Gerhard Gmaschitz, Jason Phan, Andrew Little, Jason R. Abbott, Qi Sun, Michael Gmachl, Dorothea Rudolph, Heribert Arnhof, Klaus Rumpel, Fabio Savarese, Thomas Gerstberger, Nikolai Mischerikow, Matthias Treu, Lorenz Herdeis, Tobias Wunberg, Andreas Gollner, Harald Weinstabl, Andreas Mantoulidis, Oliver Krämer, Darryl B. McConnell, Stephen W. Fesik
Publikováno v:
Journal of Medicinal Chemistry. 65:14614-14629
Autor:
Mark Jackson, Niousha Ahmari, Jianqiang Wu, Tilat A. Rizvi, Elizabeth Fugate, Mi-OK Kim, Eva Dombi, Heribert Arnhof, Guido Boehmelt, Matthias J. Düchs, Clive J. Long, Udo Maier, Francesca Trapani, Marco H. Hofmann, Nancy Ratner
Publikováno v:
J Pharmacol Exp Ther
The Journal of pharmacology and experimental therapeutics, vol 385, iss 2
The Journal of pharmacology and experimental therapeutics, vol 385, iss 2
Individuals with neurofibromatosis type 1 develop rat sarcoma virus (RAS)–mitogen-activated protein kinase–mitogen-activated and extracellular signal-regulated kinase (RAS-MAPK-MEK)–driven nerve tumors called neurofibromas. Although MEK inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4586491f3a1471bd72362287987e00
https://europepmc.org/articles/PMC10108440/
https://europepmc.org/articles/PMC10108440/
Autor:
Jürgen Moll, Natarajan Muthusamy, Norbert Kraut, Darryl B. McConnell, Mark Pearson, Segundo Gonzalez, Peter Ettmayer, Sumithira Vasu, Swagata Goswami, Girish Rajgolikar, Michael P. Sanderson, Thomas Gerstberger, Renate Schnitzer, Andreas Zoephel, Heribert Arnhof, Dirk Scharn, Jark Böttcher, Seila Lorenzo-Herrero, Marc Kerenyi, Sebastian Carotta, Maria A. Impagnatiello, Harald Engelhardt, Rajeswaran Mani, Marco H. Hofmann
Supplementary Data including Table S1-Table S5 and Figure S1 - Figure S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d553495bd4441df245e0ecc2903f83f
https://doi.org/10.1158/1535-7163.22520835
https://doi.org/10.1158/1535-7163.22520835
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Supplementary Data, Table S1, S3, S6, S8, S10-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b265e4961eac4720f5366a19b7c1c2
https://doi.org/10.1158/2159-8290.22535216
https://doi.org/10.1158/2159-8290.22535216
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Table S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1bf13695abb378067b126ed241cfc8
https://doi.org/10.1158/2159-8290.22535225
https://doi.org/10.1158/2159-8290.22535225
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Table S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6645653db29839d8ab0c10bd031b1919
https://doi.org/10.1158/2159-8290.22535219.v1
https://doi.org/10.1158/2159-8290.22535219.v1
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
KRAS is the most frequently mutated driver of pancreatic, colorectal, and non–small cell lung cancers. Direct KRAS blockade has proved challenging, and inhibition of a key downstream effector pathway, the RAF–MEK–ERK cascade, has shown limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4207250379f0cc7e1fcd4e873b0d65cb
https://doi.org/10.1158/2159-8290.c.6547790.v1
https://doi.org/10.1158/2159-8290.c.6547790.v1
Autor:
Norbert Kraut, Günther R. Adolf, Stephan K. Zahn, Ulrike Weyer-Czernilofsky, Heribert Arnhof, Thomas Pecina, Jürgen Moll, Reiner Meyer, Astrid Jeschko, Stefan Fischer, Andreas Wernitznig, Norbert Schweifer, Pilar Garin-Chesa, Marco H. Hofmann, Michael P. Sanderson
The following information of relevance to the manuscript is included: The source and authentication of all cell lines is included in Supplementary Table S1 and is of importance for validation of the results described in the manuscript. Data showing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397bd43228384ef7b7e24bf999f32077
https://doi.org/10.1158/1535-7163.22507960.v1
https://doi.org/10.1158/1535-7163.22507960.v1
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Table S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ee8f4a903b5dfb360e7672dae7df68
https://doi.org/10.1158/2159-8290.22535228
https://doi.org/10.1158/2159-8290.22535228
Autor:
Jürgen Moll, Natarajan Muthusamy, Norbert Kraut, Darryl B. McConnell, Mark Pearson, Segundo Gonzalez, Peter Ettmayer, Sumithira Vasu, Swagata Goswami, Girish Rajgolikar, Michael P. Sanderson, Thomas Gerstberger, Renate Schnitzer, Andreas Zoephel, Heribert Arnhof, Dirk Scharn, Jark Böttcher, Seila Lorenzo-Herrero, Marc Kerenyi, Sebastian Carotta, Maria A. Impagnatiello, Harald Engelhardt, Rajeswaran Mani, Marco H. Hofmann
Natural killer (NK) cells play a pivotal role in controlling cancer. Multiple extracellular receptors and internal signaling nodes tightly regulate NK activation. Cyclin-dependent kinases of the mediator complex (CDK8 and CDK19) were described as a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7267496a9a3dfd136c6ecb06ec5a6826
https://doi.org/10.1158/1535-7163.c.6542802.v1
https://doi.org/10.1158/1535-7163.c.6542802.v1