Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Heribert, Jürgens"'
Autor:
Victor Rechl, Andreas Ranft, Vivek Bhadri, Benedicte Brichard, Stephane Collaud, Sona Cyprova, Hans Eich, Torben Ek, Hans Gelderblom, Jendrik Hardes, Lianne M. Haveman, Wolfgang Hartmann, Peter Hauser, Philip Heesen, Heribert Jürgens, Jukka Kanerva, Thomas Kühne, Anna Raciborska, Jelena Rascon, Arne Streitbürger, Yasmin Uhlenbruch, Beate Timmermann, Josephine Kersting, Minh Thanh Pham, Uta Dirksen
Publikováno v:
Sarcoma, Vol 2024 (2024)
Background. Ewing sarcoma (EwS) is a rare and highly malignant bone tumor primarily affecting children, adolescents, and young adults. The pelvis, trunk, and lower extremities are the most common sites, while EwS of the sacrum as a primary site is ve
Externí odkaz:
https://doaj.org/article/58f48443d0a242e599448f03041e5ddb
Autor:
Josephine Kersting, Andreas Ranft, PhD, Vivek Bhadri, MD, PhD, Bénédicte Brichard, MD, Stéphane Collaud, MD, Sona Cyprová, MD, Hans Eich, MD, Torben Ek, MD, PhD, Hans Gelderblom, MD, PhD, Jendrik Hardes, MD, Lianne Haveman, MD, Wolfgang Hartmann, MD, Peter Hauser, MD, PhD, Philip Heesen, Heribert Jürgens, MD, Jukka Kanerva, MD, Thomas Kühne, MD, Anna Raciborska, MD, Jelena Rascon, MD, PhD, Victor Rechl, Arne Streitbürger, MD, Beate Timmermann, MD, Yasmine Uhlenbruch, MD, Uta Dirksen, MD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101269- (2023)
Purpose: Radiation therapy (RT) is an integral part of Ewing sarcoma (EwS) therapy. The Ewing 2008 protocol recommended RT doses ranging from 45 to 54 Gy. However, some patients received other doses of RT. We analyzed the effect of different RT doses
Externí odkaz:
https://doaj.org/article/2a050af236a540a68829db7ea1819246
Autor:
Giuseppina Sannino, Aruna Marchetto, Andreas Ranft, Susanne Jabar, Constanze Zacherl, Rebeca Alba-Rubio, Stefanie Stein, Fabienne S. Wehweck, Merve M. Kiran, Tilman L.B. Hölting, Julian Musa, Laura Romero-Pérez, Florencia Cidre-Aranaz, Maximilian M.L. Knott, Jing Li, Heribert Jürgens, Ana Sastre, Javier Alonso, Willian Da Silveira, Gary Hardiman, Julia S. Gerke, Martin F. Orth, Wolfgang Hartmann, Thomas Kirchner, Shunya Ohmura, Uta Dirksen, Thomas G.P. Grünewald
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 156-162 (2019)
Background: Up to 30–40% of Ewing sarcoma (EwS) patients with non-metastatic disease develop local or metastatic relapse within a time span of 2–10 years. This is in part caused by the absence of prognostic biomarkers that can identify high-risk
Externí odkaz:
https://doaj.org/article/519688e9d40c4215ae075d85d43e55cd
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Supplementary Figures S1-6. Supplementary Fig S1: Combined patient characteristics and subjected methods Supplementary Fig. S2 A: ROC curves were constructed by using the somatic scores from the sequenced genotypes. Supplementary Fig. S3: Circos plot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e66069dde343fc00689de337b82a9f
https://doi.org/10.1158/1078-0432.22459203
https://doi.org/10.1158/1078-0432.22459203
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Supplementary Materials. Additional Material and Methods section and clinical data of the Ponatib treated patient.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac54f5bd1e6ce2e1cfd6c1992425a06
https://doi.org/10.1158/1078-0432.22459200
https://doi.org/10.1158/1078-0432.22459200
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Purpose: A low mutation rate seems to be a general feature of pediatric cancers, in particular in oncofusion gene-driven tumors. Genetically, Ewing sarcoma is defined by balanced chromosomal EWS/ETS translocations, which give rise to oncogenic chimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9955f34fc024c4c397cbadc4c48654
https://doi.org/10.1158/1078-0432.c.6524157.v1
https://doi.org/10.1158/1078-0432.c.6524157.v1
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Supplementary Tables S1-6. Table S1: Validation of somatic mutations by Sanger sequencing for construction of ROC Table S2: Characteristics of the discovery data set for exome sequencing Table S3: Somatic mutations in the discovery data set (filtered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d11955cccbf221f514772713b440c3
https://doi.org/10.1158/1078-0432.22459197
https://doi.org/10.1158/1078-0432.22459197
Autor:
Poul H.B. Sorensen, Samuel A. Aparicio, Michael N. Pollak, Heribert Jürgens, Timothy J. Triche, Marco M. Gottardis, Joan M. Carboni, Steven E. McKinney, Tony L. Ng, Daniel H. Wai, Darren N. Saunders, Jenny C. Potratz
Supplementary Materials, Table 1-2, Figures 1-5 from Synthetic Lethality Screens Reveal RPS6 and MST1R as Modifiers of Insulin-like Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ace675f963fc90b3013b13a86195894
https://doi.org/10.1158/0008-5472.22387443.v1
https://doi.org/10.1158/0008-5472.22387443.v1
Autor:
Stefan K. Zöllner, Katja L. Kauertz, Isabelle Kaiser, Maximilian Kerkhoff, Christiane Schaefer, Madita Tassius, Susanne Jabar, Heribert Jürgens, Ruth Ladenstein, Thomas Kühne, Lianne M. Haveman, Michael Paulussen, Andreas Ranft, Uta Dirksen
Publikováno v:
Cancers; Volume 14; Issue 23; Pages: 5935
OA Förderung 2022 Ewing sarcoma (EwS) is the second most common bone and soft tissue tumor, affecting primarily adolescents and young adults. Patients with secondary EwS are excluded from risk stratification in several studies and therefore do not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ab11fa69c06daddc4f8898e748d850
https://pubmed.ncbi.nlm.nih.gov/36497417
https://pubmed.ncbi.nlm.nih.gov/36497417
Publikováno v:
Klinische Pädiatrie. 232:289-293
Zusammenfassung Hintergrund Die pädiatrisch-onkologische Versorgungsstruktur nimmt in Deutschland eine Sonderrolle ein. An Krebs erkrankte Kinder und Jugendliche werden bundesweit einheitlich in Therapiestudien und Registern sektorenübergreifend an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1675905d62af9ba7f63f5f0478b613b9
https://doi.org/10.1055/a-1158-9341
https://doi.org/10.1055/a-1158-9341