Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Hereditary Hemochromatosis Protein"'
Autor:
Scott J. Garforth, Dick J Sjöström, Ana I. Teixeira, Camilla Mohlin, Sinisa Bjelic, Elena Ambrosetti
Publikováno v:
The FEBS Journal. 289:2935-2947
Human transferrin receptor 1 (TfR) is necessary for delivery of the iron carrier protein transferrin into cells and can be utilized for targeted delivery across cellular membranes. Binding of transferrin to the receptor is regulated by hereditary hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecfe520a9fb2c8f5d210e93dbd69691
https://doi.org/10.1111/febs.16311
https://doi.org/10.1111/febs.16311
Autor:
Ferdinand Schweser, Robert Zivadinov, Murali Ramanathan, Bianca Weinstock-Guttman, Jesper Hagemeier, Fuchun Lin, Niels Bergsland, Michael G. Dwyer
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 17, Iss, Pp 530-540 (2018)
NeuroImage: Clinical, Vol 17, Iss, Pp 530-540 (2018)
Brain iron homeostasis is known to be disturbed in multiple sclerosis (MS), yet little is known about the association of common gene variants linked to iron regulation and pathological tissue changes in the brain. In this study, we investigated the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6b8e4737c6285d408e1897446794f3
https://pubmed.ncbi.nlm.nih.gov/29201641
https://pubmed.ncbi.nlm.nih.gov/29201641
Publikováno v:
European Journal of Immunology. 44:1604-1614
MHC class I (MHC I) antigen presentation is a ubiquitous process by which cells present endogenous proteins to CD8(+) T lymphocytes during immune surveillance and response. Hereditary hemochromatosis protein, HFE, is involved in cellular iron uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0790e268e3842921fb86fc08d309c8ee
https://doi.org/10.1002/eji.201343955
https://doi.org/10.1002/eji.201343955
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Gastroenterology and Hepatology. 28:1087-1094
Hereditary hemochromatosis (HH) is a widely recognized and well-studied condition in European populations. This is largely due to the high prevalence of the C282Y mutation of HFE. Although less common than in Europe, HH cases have been reported in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd5b272caf2e97e8667a0fea4fe7337
https://doi.org/10.1111/jgh.12222
https://doi.org/10.1111/jgh.12222
Publikováno v:
Journal of Clinical Investigation. 123:2337-2343
Hepcidin is a key hormone that is involved in the control of iron homeostasis in the body. Physiologically, hepcidin is controlled by iron stores, inflammation, hypoxia, and erythropoiesis. The regulation of hepcidin expression by iron is a complex p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abccb5627b87a478d63886cbd90d0c19
https://doi.org/10.1172/jci67225
https://doi.org/10.1172/jci67225
Autor:
Caroline A. Enns, Junwei Gao, Juxing Chen, Hidekazu Tsukamoto, An Sheng Zhang, Maxwell Kramer
Publikováno v:
Cell Metabolism. 9(3):217-227
Summary The mechanisms that allow the body to sense iron levels in order to maintain iron homeostasis are unknown. Patients with the most common form of hereditary iron overload have mutations in the hereditary hemochromatosis protein HFE. They have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ccc24f124d9b29587235b493d1a403
Publikováno v:
Journal of Biological Chemistry. 283:21462-21468
Lack of functional hereditary hemochromatosis protein, HFE, causes iron overload predominantly in hepatocytes, the major site of HFE expression in the liver. In this study, we investigated the role of HFE in the regulation of both transferrin-bound i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a1c989a1ae8cf10359f4a8ec49bc83
https://doi.org/10.1074/jbc.m803150200
https://doi.org/10.1074/jbc.m803150200
Autor:
Alessandro Castiglione, Giulia Zeri, Claudia Aimoni, Andrea Ciorba, Elisa Orioli, Donato Gemmati, Marco Vigliano
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Background. Even if various pathophysiological events have been proposed as explanations, the putative cause of sudden hearing loss remains unclear.Objectives. To investigate and to reveal associations (if any) between the main iron-related gene vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dc6cf7fa203115b2b00bcd64f87586
http://hdl.handle.net/11577/3225621
http://hdl.handle.net/11577/3225621
