Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Herbert Tschochner"'
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283698 (2023)
RpS0/uS2, rpS2/uS5, and rpS21/eS21 form a cluster of ribosomal proteins (S0-cluster) at the head-body junction near the central pseudoknot of eukaryotic small ribosomal subunits (SSU). Previous work in yeast indicated that S0-cluster assembly is requ
Externí odkaz:
https://doaj.org/article/f578d748e3354dec82dd25fe2cc73c2f
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0252497 (2021)
In yeast and human cells many of the ribosomal proteins (r-proteins) are required for the stabilisation and productive processing of rRNA precursors. Functional coupling of r-protein assembly with the stabilisation and maturation of subunit precursor
Externí odkaz:
https://doaj.org/article/fae3b58576594e1fa035300ec550abd2
Autor:
Tommy Darrière, Michael Pilsl, Marie-Kerguelen Sarthou, Adrien Chauvier, Titouan Genty, Sylvain Audibert, Christophe Dez, Isabelle Léger-Silvestre, Christophe Normand, Anthony K Henras, Marta Kwapisz, Olga Calvo, Carlos Fernández-Tornero, Herbert Tschochner, Olivier Gadal
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008157 (2019)
Most transcriptional activity of exponentially growing cells is carried out by the RNA Polymerase I (Pol I), which produces a ribosomal RNA (rRNA) precursor. In budding yeast, Pol I is a multimeric enzyme with 14 subunits. Among them, Rpa49 forms wit
Externí odkaz:
https://doaj.org/article/c330ec3874884274aab2d5ed7dfd1bc5
Autor:
Katharina Hannig, Virginia Babl, Kristin Hergert, Andreas Maier, Michael Pilsl, Christopher Schächner, Ulrike Stöckl, Philipp Milkereit, Herbert Tschochner, Wolfgang Seufert, Joachim Griesenbeck
Publikováno v:
PLoS Genetics, Vol 15, Iss 2, p e1008006 (2019)
RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA) in all eukaryotes, accounting for the major part of transcriptional activity in proliferating cells. Although basal Pol I transcription factors have been characterized in diverse organisms, th
Externí odkaz:
https://doaj.org/article/eccc7aa5c50a44fdb87e85e67cf887df
Autor:
Jan Linnemann, Gisela Pöll, Steffen Jakob, Sébastien Ferreira-Cerca, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0203415 (2019)
Many of the small ribosomal subunit proteins are required for the stabilisation of late small ribosomal subunit (SSU) precursors and for final SSU rRNA processing in S. cerevisiae. Among them are ribosomal proteins (r-proteins) which form a protein c
Externí odkaz:
https://doaj.org/article/f4fff90ab1e7462795ae07e097177ac5
Autor:
Michael Pilsl, Corinne Crucifix, Gabor Papai, Ferdinand Krupp, Robert Steinbauer, Joachim Griesenbeck, Philipp Milkereit, Herbert Tschochner, Patrick Schultz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Eukaryotic RNA polymerase I (Pol I) is responsible for the transcription of rRNA genes. Here the authors determine the cryo-EM structure of the Pol I-Rrn3 complex, providing insight into how Rrn3 stabilizes the monomeric initiation competent Pol I to
Externí odkaz:
https://doaj.org/article/6aa07fa9078d4b249ab94428a0822512
Autor:
Gisela Pöll, Christian Müller, Malena Bodden, Fabian Teubl, Norbert Eichner, Gerhard Lehmann, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179405 (2017)
Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of r
Externí odkaz:
https://doaj.org/article/9fc58937cb004efe969197c05cacf8b7
Autor:
Uli Ohmayer, Álvaro Gil-Hernández, Martina Sauert, Pilar Martín-Marcos, Mercedes Tamame, Herbert Tschochner, Joachim Griesenbeck, Philipp Milkereit
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143768 (2015)
Cellular production of ribosomes involves the formation of highly defined interactions between ribosomal proteins (r-proteins) and ribosomal RNAs (rRNAs). Moreover in eukaryotic cells, efficient ribosome maturation requires the transient association
Externí odkaz:
https://doaj.org/article/75ba9da7f9a24d76ae0b858e6f4e7445
Autor:
Uli Ohmayer, Michael Gamalinda, Martina Sauert, Julius Ossowski, Gisela Pöll, Jan Linnemann, Thomas Hierlmeier, Jorge Perez-Fernandez, Beril Kumcuoglu, Isabelle Leger-Silvestre, Marlène Faubladier, Joachim Griesenbeck, John Woolford, Herbert Tschochner, Philipp Milkereit
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68412 (2013)
During the assembly process of ribosomal subunits, their structural components, the ribosomal RNAs (rRNAs) and the ribosomal proteins (r-proteins) have to join together in a highly dynamic and defined manner to enable the efficient formation of funct
Externí odkaz:
https://doaj.org/article/ee9ee19dd4c54b10a8a7b01a7de8532d
Autor:
Steffen Jakob, Uli Ohmayer, Andreas Neueder, Thomas Hierlmeier, Jorge Perez-Fernandez, Eduard Hochmuth, Rainer Deutzmann, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32552 (2012)
Early steps of eukaryotic ribosome biogenesis require a large set of ribosome biogenesis factors which transiently interact with nascent rRNA precursors (pre-rRNA). Most likely, concomitant with that initial contacts between ribosomal proteins (r-pro
Externí odkaz:
https://doaj.org/article/67498a25b4c84a299f8fe7305eb6c95c