Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Herbert Steinbeißer"'
Autor:
Marta Vitorino, Ana Cristina Silva, José Manuel Inácio, José Silva Ramalho, Michal Gur, Abraham Fainsod, Herbert Steinbeisser, José António Belo
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135504 (2015)
Protein Kinase Domain Containing, Cytoplasmic (PKDCC) is a protein kinase which has been implicated in longitudinal bone growth through regulation of chondrocytes formation. Nevertheless, the mechanism by which this occurs remains unknown. Here, we i
Externí odkaz:
https://doaj.org/article/5fd93be4fcaa495d96ec37dd570b4343
Publikováno v:
Differentiation. 93:27-38
The Wnt/planar cell polarity (PCP) pathway directs cell migration during vertebrate gastrulation and is essential for proper embryonic development. Paraxial protocadherin (PAPC, Gene Symbol pcdh8.2) is an important activator of Wnt/PCP signaling duri
Expression of the ALK1 family of type I BMP/ADMP receptors during gastrula stages in Xenopus embryos
Publikováno v:
The International Journal of Developmental Biology. 61:465-470
Multiple members of the transforming growth factor beta (TGFβ) family of secreted factors play central inductive and patterning roles during embryogenesis. During gastrulation in vertebrates, the bone morphogenetic protein (BMP) sub-family is linked
Autor:
Philipp Andre, Sabrina Kurz, Melanie Tingler, Markus Maerker, Bärbel Ulmer, Herbert Steinbeißer, Axel Schweickert, Martin Blum, Kirsten Deißler, Dina Mönch, Thomas Thumberger, Abraham Fainsod, Marina Campione, Mark Lewandoski
Publikováno v:
Scientific Reports
Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned during later embryogenesis, the role of Gsc in the organizer has remained enigmatic. Using conditional gain-of-function app
Autor:
Hideki Yokoyama, Sabine Merker, Justus Tegha-Dunghu, Stefanie Draeger, Dmytro Mayilo, Burkhard Hoeckendorf, Thomas Ruppert, Holger Lorenz, Joachim Wittbrodt, Maren Klinger, Stephanie Freiss, Ivana Cado, Daigo Inoue, Oliver J. Gruss, Herbert Steinbeisser, Kerstin Hupfeld, Felix Bärenz, Sahra Pilz
Publikováno v:
The Journal of Cell Biology
SSX2IP promotes centrosome maturation and maintenance at the onset of vertebrate development, preserving centrosome integrity and mitosis during rapid cleavage divisions and in somatic cells.
Meiotic maturation in vertebrate oocytes is an excell
Meiotic maturation in vertebrate oocytes is an excell
Publikováno v:
The Journal of Cell Biology
Wnt-11/frizzled-7 reduces the lateral clustering of C-cadherin by capturing the protocadherin PAPC and C-cadherin into distinct adhesion-modulating complexes.
Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent
Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent
Publikováno v:
EMBO reports. 13:129-134
Xenopus paraxial protocadherin (PAPC) regulates cadherin-mediated cell adhesion and promotes the planar cell polarity (PCP) pathway. Here we report that PAPC functions in the Xenopus gastrula as an inhibitor of the Wnt/β-catenin pathway. The intrace
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 1:294-300
Tissue border formation is an important process that prevents mixing of cells during embryonic development. The establishment of tissue borders is not a trivial problem, particularly in early embryos when cells and tissues are not fully differentiate
Publikováno v:
Development Genes and Evolution. 221:29-41
Cerberus-related molecules are well-known Wnt, Nodal, and BMP inhibitors that have been implicated in different processes including anterior–posterior patterning and left–right asymmetry. In both mouse and frog, two Cerberus-related genes have be
Autor:
Benoit G. Bruneau, Anne Glaser, Herbert Steinbeisser, Alessandro D. Mori, Gudrun A. Rappold, Rüdiger J. Blaschke, Katja U. Schneider, Stefanie Schmitteckert, Sandra Puskaric
Publikováno v:
Human Molecular Genetics
Heart formation requires a highly balanced network of transcriptional activation of genes. The homeodomain transcription factor, Shox2, is essential for the formation of the sinoatrial valves and for the development of the pacemaking system. The eluc