Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Herbert Stangl"'
Autor:
Stefanie Steinbauer, Alice König, Cathrina Neuhauser, Bettina Schwarzinger, Herbert Stangl, Marcus Iken, Julian Weghuber, Clemens Röhrl
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cholesterol deposition in intimal macrophages leads to foam cell formation and atherosclerosis. Reverse cholesterol transport (RCT), initiated by efflux of excess cholesterol from foam cells, counteracts atherosclerosis. However, targeting R
Externí odkaz:
https://doaj.org/article/00bf50f0f31c46ada9dc0a8e8d00b5e6
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102089- (2023)
Summary: Tracer techniques to assess very-low-density lipoprotein (VLDL) secretion in humans are expensive, are time consuming, and require mathematical models to estimate VLDL kinetics. Here, we describe an alternative, time- and cost-efficient prot
Externí odkaz:
https://doaj.org/article/d397c16d5a7b4d4bb77343d1461a0c94
Autor:
Verena Hiebl, Daniel Schachner, Angela Ladurner, Elke H. Heiss, Herbert Stangl, Verena M. Dirsch
Publikováno v:
Biological Procedures Online, Vol 22, Iss 1, Pp 1-18 (2020)
Abstract Background The human Caco-2 cell line is a common in vitro model of the intestinal epithelial barrier. As the intestine is a major interface in cholesterol turnover and represents a non-biliary pathway for cholesterol excretion, Caco-2 cells
Externí odkaz:
https://doaj.org/article/9ddfc7e53c2d4ee3b061c80f48780af7
Autor:
Sigrid Vondra, Victoria Kunihs, Tana Eberhart, Karin Eigner, Raimund Bauer, Peter Haslinger, Sandra Haider, Karin Windsperger, Günter Klambauer, Birgit Schütz, Mario Mikula, Xiaowei Zhu, Alexander E. Urban, Roberta L. Hannibal, Julie Baker, Martin Knöfler, Herbert Stangl, Jürgen Pollheimer, Clemens Röhrl
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 11, Pp 1922-1934 (2019)
During pregnancy, extravillous trophoblasts (EVTs) invade the maternal decidua and remodel the local vasculature to establish blood supply for the growing fetus. Compromised EVT function has been linked to aberrant pregnancy associated with maternal
Externí odkaz:
https://doaj.org/article/f74acbe79c894b78b6402448b83db2fa
Autor:
Khanichi N. Charles, Janis E. Shackelford, Phyllis L. Faust, Steven J. Fliesler, Herbert Stangl, Werner J. Kovacs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cholesterol biosynthesis is a multi-step process involving several subcellular compartments, including peroxisomes. Cells adjust their sterol content by both transcriptional and post-transcriptional feedback regulation, for which sterol regulatory el
Externí odkaz:
https://doaj.org/article/f0eb6466aaf148c3937de0abf3ce0f21
Autor:
Annika Brandau, Nahla Ibrahim, Johannes Klopf, Hubert Hayden, Maria Ozsvar-Kozma, Taras Afonyushkin, Sonja Bleichert, Lukas Fuchs, Viktoria Watzinger, Verena Nairz, Emely Manville, Veronika Kessler, Herbert Stangl, Wolf Eilenberg, Christoph Neumayer, Christine Brostjan
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 217 (2022)
Neutrophil extracellular traps (NETs) are DNA–protein structures released by neutrophils in response to various stimuli, including oxidized, low-density lipoprotein (oxLDL). Accumulating evidence suggests a role for NETs in the pathogenesis of abdo
Externí odkaz:
https://doaj.org/article/12ec5566ec4d4135ae58854e402ffa0e
Autor:
Martin Forsthuber, Andreas Marius Kaiser, Sebastian Granitzer, Ingrid Hassl, Markus Hengstschläger, Herbert Stangl, Claudia Gundacker
Publikováno v:
Environment International, Vol 137, Iss , Pp - (2020)
Perfluoroalkyl (PFAS) substances are widespread in the environment and in organisms. The fact that exposure to PFAS is associated with elevated cholesterol levels is a major concern for human health. Previous investigations, in which bovine serum alb
Externí odkaz:
https://doaj.org/article/6d5bdcfa3e274ce591be47fa9bfa7f81
Autor:
Markus Axmann, Birgit Plochberger, Mario Mikula, Florian Weber, Witta Monika Strobl, Herbert Stangl
Publikováno v:
Membranes, Vol 11, Iss 11, p 882 (2021)
Cholesterol is one of the main constituents of plasma membranes; thus, its supply is of utmost importance. This review covers the known mechanisms of cholesterol transfer from circulating lipoprotein particles to the plasma membrane, and vice versa.
Externí odkaz:
https://doaj.org/article/db336cda79b445d08cc3975682c81671
Autor:
Limei Wang, Veronika Palme, Nicole Schilcher, Angela Ladurner, Elke H. Heiss, Herbert Stangl, Rudolf Bauer, Verena M. Dirsch, Atanas G. Atanasov
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
We report increased cholesterol efflux from macrophages in the presence of falcarindiol, an important dietary constituent present in commonly used vegetables and medicinal plants. Falcarindiol (3–20 μM) increased cholesterol efflux from THP-1-deri
Externí odkaz:
https://doaj.org/article/28ec044aadc84ed69029636e5400f358
Autor:
Clemens Röhrl, Karin Eigner, Katharina Winter, Melanie Korbelius, Sascha Obrowsky, Dagmar Kratky, Werner J. Kovacs, Herbert Stangl
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 1, Pp 94-103 (2014)
Metabolic disorders such as type 2 diabetes cause hepatic endoplasmic reticulum (ER) stress, which affects neutral lipid metabolism. However, the role of ER stress in cholesterol metabolism is incompletely understood. Here, we show that induction of
Externí odkaz:
https://doaj.org/article/14aa0f6ee53e4a5c82b316d0efa5417c