Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Herbert Schwegler"'
Autor:
Syed Ahsan Raza, Anne Albrecht, Gürsel Çalışkan, Bettina Müller, Yunus Emre Demiray, Susann Ludewig, Susanne Meis, Nicolai Faber, Roland Hartig, Burkhart Schraven, Volkmar Lessmann, Herbert Schwegler, Oliver Stork
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Intra-hippocampal circuits are essential for associating a background context with behaviorally salient stimuli and involve cholinergic modulation at SST+ interneurons. Here the authors show that the salience of the background context memory is modul
Externí odkaz:
https://doaj.org/article/bb2ce21df8184b16927e262706f74ba5
Autor:
Elodie De Bruyckere, Ruth Simon, Sigrun Nestel, Bernd Heimrich, Dennis Kätzel, Alexei V. Egorov, Pentao Liu, Nancy A. Jenkins, Neal G. Copeland, Herbert Schwegler, Andreas Draguhn, Stefan Britsch
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Structural and functional plasticity of synapses are critical neuronal mechanisms underlying learning and memory. While activity-dependent regulation of synaptic strength has been extensively studied, much less is known about the transcriptional cont
Externí odkaz:
https://doaj.org/article/f45444714dda4daaa8e4d24be3dd0b32
Autor:
Robert Lübkemann, Judith Eberhardt, Friedrich-Wilhelm Röhl, Kathrin Janitzky, Sven Nullmeier, Oliver Stork, Herbert Schwegler, Rüdiger Linke
Publikováno v:
Brain Sciences, Vol 5, Iss 3, Pp 299-317 (2015)
GABAergic local circuit neurons are critical for the network activity and functional interaction of the amygdala and hippocampus. Previously, we obtained evidence for a GABAergic contribution to the hippocampal projection into the basolateral amygdal
Externí odkaz:
https://doaj.org/article/2aa7bfeb21ad4922a3fdd8b1a52f1ad8
Autor:
Christina Spilker, Sven Nullmeier, Katarzyna M Grochowska, Anne Schumacher, Ioana Butnaru, Tamar Macharadze, Guilherme M Gomes, PingAn Yuanxiang, Gonca Bayraktar, Carolin Rodenstein, Carolin Geiseler, Angela Kolodziej, Jeffrey Lopez-Rojas, Dirk Montag, Frank Angenstein, Julia Bär, Wolfgang D'Hanis, Thomas Roskoden, Marina Mikhaylova, Eike Budinger, Frank W Ohl, Oliver Stork, Ana C Zenclussen, Anna Karpova, Herbert Schwegler, Michael R Kreutz
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005907 (2016)
Jacob, the protein encoded by the Nsmf gene, is involved in synapto-nuclear signaling and docks an N-Methyl-D-Aspartate receptor (NMDAR)-derived signalosome to nuclear target sites like the transcription factor cAMP-response-element-binding protein (
Externí odkaz:
https://doaj.org/article/be102f6df7474cccbf12c201592fe231
Autor:
Rolf Sprengel, Raul Guzman, Vivan Nguyen Chi, Barbara Schindeldecker, Petra Weißgerber, Veit Flockerzi, Jörg Pohle, Dieter Bruns, Jenny Bröker‐Lai, Georg Köhr, Martin Both, Andreas Draguhn, Herbert Schwegler, Astrid Kollewe, Alan Lai, Bernd Fakler, Yvonne Schwarz, Marc Freichel, Ilka Mathar, Alexander Dietrich
Publikováno v:
The EMBO Journal
Canonical transient receptor potential (TRPC) channels influence various neuronal functions. Using quantitative high‐resolution mass spectrometry, we demonstrate that TRPC1, TRPC4, and TRPC5 assemble into heteromultimers with each other, but not wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90de2c54fafcb9257bbf32cf9d7798cf
https://doi.org/10.15252/embj.201696369
https://doi.org/10.15252/embj.201696369
Autor:
Susann Ludewig, Nicolai Faber, Volkmar Lessmann, Anne Albrecht, Gürsel Çalışkan, Roland Hartig, Oliver Stork, Susanne Meis, Yunus Emre Demiray, Burkhart Schraven, Syed Ahsan Raza, Bettina Müller, Herbert Schwegler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Cholinergic neuromodulation in the hippocampus controls the salience of background context memory acquired in the presence of elemental stimuli predicting an aversive reinforcement. With pharmacogenetic inhibition we here demonstrate that hilar perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2db03f3d859e149dc8dd3f36c6ddc4
https://doaj.org/article/bb2ce21df8184b16927e262706f74ba5
https://doaj.org/article/bb2ce21df8184b16927e262706f74ba5
Publikováno v:
Behavioural Brain Research. 322:177-185
Neuregulins (Nrg) are a gene family that binds to tyrosine kinase receptors of the ErbB family. The protein of Nrg1 is to be involved in heart formation, migration of neurons, axonal pathfinding and synaptic function. A relation between Nrg1 and schi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eef7205785d3ac65c098bee922c9083
https://doi.org/10.1016/j.bbr.2017.01.022
https://doi.org/10.1016/j.bbr.2017.01.022
Autor:
Rochelle N, Wickramasekara, Charles, Bockman, Joachim, Hanke, Herbert, Schwegler, JoAnn, McGee, Edward, Walsh, Deniz, Yilmazer-Hanke
Publikováno v:
Pharmacology, biochemistry, and behavior. 188
Patients with anxiety disorders and posttraumatic stress disorder (PTSD) exhibit exaggerated fear responses and noradrenergic dysregulation. Fear-related responses to α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::235cc86e46ff792456bb3fa9542e02f7
https://pubmed.ncbi.nlm.nih.gov/31805289
https://pubmed.ncbi.nlm.nih.gov/31805289
Publikováno v:
Neuroscience Letters. 632:114-118
The cholinergic and dopaminergic innervation of the amygdala plays an important role in attention, emotional arousal, aversive forms of associative learning, conditioned responses, and stress responsivity. Roman High- (RHA) and Low-Avoidance (RLA) ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e72b4538751651cdd8c3f838a23ede
https://doi.org/10.1016/j.neulet.2016.08.053
https://doi.org/10.1016/j.neulet.2016.08.053
Autor:
F. A. Seigfried, Stefan Britsch, J. Fischer, Ruth Simon, Pentao Liu, Herbert Schwegler, E. De Bruyckere, Nancy A. Jenkins, L. Baumann, Neal G. Copeland
Publikováno v:
Genes, Brain, and Behavior
The dentate gyrus is one of the only two brain regions where adult neurogenesis occurs. Throughout life, cells of the neuronal stem cell niche undergo proliferation, differentiation and integration into the hippocampal neural circuitry. Ongoing adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c850b14e93c9ea5c79aa6f169f0ff5
https://doi.org/10.1111/gbb.12287
https://doi.org/10.1111/gbb.12287