Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Herbert Schramek"'
Autor:
Glory Ranches, Maximilian Zeidler, Roman Kessler, Martina Hoelzl, Michael W. Hess, Jonathan Vosper, Paul Perco, Herbert Schramek, Kai K. Kummer, Michaela Kress, Anne Krogsdam, Michael Rudnicki, Gert Mayer, Alexander Huettenhofer
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 794-813 (2022)
Exosomes have emerged as a valuable repository of novel biomarkers for human diseases such as chronic kidney disease (CKD). From a healthy control group, we performed microRNA (miRNA) profiling of urinary exosomes and compared it with a cell culture
Externí odkaz:
https://doaj.org/article/e1639b6ba0ef48189e6285e9a9680784
Autor:
Glory Ranches, Melanie Lukasser, Herbert Schramek, Andreas Ploner, Taras Stasyk, Gert Mayer, Günter Mayer, Alexander Hüttenhofer
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 198-210 (2017)
Chronic kidney disease (CKD) is a progressive pathological condition marked by a gradual loss of kidney function. Treatment of CKD is most effective when diagnosed at an early stage and patients are still asymptomatic. However, current diagnostic bio
Externí odkaz:
https://doaj.org/article/e6cf803a91814233b0120d2e53b9cf7e
Autor:
Markus Pirklbauer, Sebastian Sallaberger, Petra Staudinger, Ulrike Corazza, Johannes Leierer, Gert Mayer, Herbert Schramek
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5089 (2021)
SGLT2 inhibitor-related nephroprotection is—at least partially—mediated by anti-inflammatory drug effects, as previously demonstrated in diabetic animal and human studies, as well as hyperglycemic cell culture models. We recently presented first
Externí odkaz:
https://doaj.org/article/d50d7b4aafc7461698f532e4d1e9cd63
Autor:
Markus Pirklbauer, Maximilian Bernd, Lisa Fuchs, Petra Staudinger, Ulrike Corazza, Johannes Leierer, Gert Mayer, Herbert Schramek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8189 (2020)
SGLT2 inhibitors (SGLT2i) slow the progression of chronic kidney disease; however, evidence for the underlying molecular mechanisms is scarce. We investigated SGLT2i-mediated effects on differential gene expression in two independent human proximal t
Externí odkaz:
https://doaj.org/article/1f22ea43d5244dd79ff8772f91ec36b8
Autor:
Glory Ranches, Maximilian Zeidler, Roman Kessler, Martina Hoelzl, Michael W. Hess, Jonathan Vosper, Paul Perco, Herbert Schramek, Kai K. Kummer, Michaela Kress, Anne Krogsdam, Michael Rudnicki, Gert Mayer, Alexander Huettenhofer
Publikováno v:
Molecular therapy. Nucleic acids. 28
Exosomes have emerged as a valuable repository of novel biomarkers for human diseases such as chronic kidney disease (CKD). From a healthy control group, we performed microRNA (miRNA) profiling of urinary exosomes and compared it with a cell culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3094cc6c036a5fed7d9df48926ecb4c5
https://pubmed.ncbi.nlm.nih.gov/35664695
https://pubmed.ncbi.nlm.nih.gov/35664695
Autor:
Georg Kern, Sabine M Mair, Susie-Jane Noppert, Paul Jennings, Herbert Schramek, Michael Rudnicki, Gerhard A Mueller, Gert Mayer, Christian Koppelstaetter
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96377 (2014)
Chronic nephrotoxicity of immunosuppressives is one of the main limiting factors in the long-term outcome of kidney transplants, leading to tissue fibrosis and ultimate organ failure. The cytokine TGF-β is considered a key factor in this process. In
Externí odkaz:
https://doaj.org/article/10e455b48af749beb80c0fc114b5d2f8
Autor:
Herbert Schramek, Markus Pirklbauer, Gert Mayer, Johannes Leierer, Ulrike Corazza, Sebastian Sallaberger, Petra Staudinger
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5089, p 5089 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
SGLT2 inhibitor-related nephroprotection is—at least partially—mediated by anti-inflammatory drug effects, as previously demonstrated in diabetic animal and human studies, as well as hyperglycemic cell culture models. We recently presented first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a92a16ac4e11d50d431c2dd4009ccf
https://www.mdpi.com/1422-0067/22/10/5089
https://www.mdpi.com/1422-0067/22/10/5089
Autor:
Johannes Leierer, Ulrike Corazza, Gert Mayer, Markus Pirklbauer, Herbert Schramek, Petra Staudinger, Lisa Fuchs, Maximilian Bernd
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8189, p 8189 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8189, p 8189 (2020)
SGLT2 inhibitors (SGLT2i) slow the progression of chronic kidney disease
however, evidence for the underlying molecular mechanisms is scarce. We investigated SGLT2i-mediated effects on differential gene expression in two independent human proxim
however, evidence for the underlying molecular mechanisms is scarce. We investigated SGLT2i-mediated effects on differential gene expression in two independent human proxim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013ef2566b1101408a1ac13353d2b5b9
Autor:
Markus Pirklbauer, Sebastian Sallaberger, Johannes Leierer, Lisa Fuchs, Ulrike Corazza, Herbert Schramek, Gert Mayer, Petra Staudinger, Ramona Schupart
Publikováno v:
American journal of physiology. Renal physiology. 316(3)
Large clinical trials demonstrated that SGLT2 inhibitors (SGLT2i) slow the progression of kidney function decline in type 2 diabetes. Because the underlying molecular mechanisms are largely unknown, we studied the effects of SGLT2i on gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba2d7ad3ab4f85ddfea6386102f2a21
https://pubmed.ncbi.nlm.nih.gov/30539648
https://pubmed.ncbi.nlm.nih.gov/30539648
Autor:
Susie-Jane Noppert, Regina Grillari-Voglauer, Markus Pirklbauer, Andreas Kronbichler, Rita Sarközi, Johannes Grillari, Gert Mayer, Herbert Schramek, Christine Hauser, Viktoria Maria Haller
Publikováno v:
American Journal of Physiology-Renal Physiology
AJP: Renal Physiology; Vol 301
AJP: Renal Physiology; Vol 301
Matricellular proteins in the kidney have been associated with the development of tubulointerstitial fibrogenesis and the progression of renal disease. This study investigated potential antifibrotic effects of the cytokine oncostatin M (OSM) in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5a4b206796f7f136b55583ce69837a