Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Herbert P Schweizer"'
Autor:
Grace I Borlee, Brooke A Plumley, Kevin H Martin, Nawarat Somprasong, Mihnea R Mangalea, M Nurul Islam, Mary N Burtnick, Paul J Brett, Ivo Steinmetz, David P AuCoin, John T Belisle, Dean C Crick, Herbert P Schweizer, Bradley R Borlee
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005689 (2017)
Burkholderia pseudomallei, the causative agent of melioidosis, is an important public health threat due to limited therapeutic options for treatment. Efforts to improve therapeutics for B. pseudomallei infections are dependent on the need to understa
Externí odkaz:
https://doaj.org/article/a985b18871ff4468b755b783f656ed6d
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 4, p e0005571 (2017)
Burkholderia pseudomallei (Bp) causes the disease melioidosis. The main cause of mortality in this disease is septic shock triggered by the host responding to lipopolysaccharide (LPS) components of the Gram-negative outer membrane. Bp LPS is thought
Externí odkaz:
https://doaj.org/article/b7097648ecdd4cd2bebfa14ec942af1e
Autor:
Michael H Norris, Yun Heacock-Kang, Jan Zarzycki-Siek, Andrew P Bluhm, Ian A McMillan, Herbert P Schweizer, Tung T Hoang
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189018 (2017)
Burkholderia spp. are genetically and physiologically diverse. Some strains are naturally transformable and capable of DNA catabolism. Burkholderia pseudomallei (Bp) strains 1026b and K96243 and B. thailandensis strain E264 are able to utilize DNA as
Externí odkaz:
https://doaj.org/article/9dadebfb7c7448368da264b1bd7e795f
Autor:
Pacharapong Khrongsee, Jedsada Kaewrakmuk, Mariam Alami-Rose, Kuttichantran Subramaniam, Thomas B. Waltzek, Herbert P. Schweizer, Apichai Tuanyok
Publikováno v:
Frontiers in Bacteriology, Vol 3 (2024)
IntroductionBurkholderia pseudomallei, a Gram-negative bacterium inhabiting soil and fresh water, is the causative agent of melioidosis, a formidable disease in the tropics. The emergence of antibiotic resistance and the extended duration of treatmen
Externí odkaz:
https://doaj.org/article/cc9fc4af94ca4cdbb6131cd04e2f1bbe
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Several members of the genus Burkholderia are prominent pathogens. Infections caused by these bacteria are difficult to treat because of significant antibiotic resistance. Virtually all Burkholderia species are also resistant to polymyxin, prohibitin
Externí odkaz:
https://doaj.org/article/4c56afe10aea42f2b8e16a3d1a8ac020
Autor:
Zhenxin Sun, Yun Kang, Michael H Norris, Ryan M Troyer, Mike S Son, Herbert P Schweizer, Steven W Dow, Tung T Hoang
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103778 (2014)
Pseudomonas aeruginosa can grow to very high-cell-density (HCD) during infection of the cystic fibrosis (CF) lung. Phosphatidylcholine (PC), the major component of lung surfactant, has been hypothesized to support HCD growth of P. aeruginosa in vivo.
Externí odkaz:
https://doaj.org/article/a0b44449e5ee45c296f746a7540077ad
Autor:
Mercedes Gonzalez-Juarrero, Naoko Mima, Lily A Trunck, Herbert P Schweizer, Richard A Bowen, Kyle Dascher, Waithaka Mwangi, Torsten M Eckstein
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80368 (2013)
Melioidosis is a disease in tropical and subtropical regions of the world that is caused by Burkholderia pseudomallei. In endemic regions the disease occurs primarily in humans and goats. In the present study, we used the goat as a model to dissect t
Externí odkaz:
https://doaj.org/article/1dec08ab69a2428cb125dcc1179b9601
Autor:
Mary N Burtnick, Christian eHeiss, Rosemary A Roberts, Herbert P Schweizer, Parastoo eAzadi, Paul J Brett
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
Burkholderia pseudomallei and Burkholderia mallei, the etiologic agents of melioidosis and glanders respectively, cause severe disease in humans and animals and are considered potential agents of biological warfare and terrorism. Diagnosis and treatm
Externí odkaz:
https://doaj.org/article/324efb885fcc49e2bf93e2eafae519b5
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1715 (2012)
Burkholderia pseudomallei is a mostly saprophytic bacterium, but can infect humans where it causes the difficult-to-manage disease melioidosis. Even with proper diagnosis and prompt therapeutic interventions mortality rates still range from >20% in N
Externí odkaz:
https://doaj.org/article/3628064ee1374b509d68bd060b9d7c4c
Autor:
Herbert P Schweizer, Kyoung-Hee Choi
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45646 (2012)
BACKGROUND: The FabAB pathway is one of the unsaturated fatty acid (UFA) synthesis pathways for Pseudomonas aeruginosa. It was previously noted that this operon was upregulated in biofilms and repressed by exogenous UFAs. Deletion of a 30 nt fabA ups
Externí odkaz:
https://doaj.org/article/34c33c3d3d744bf99441ad773f62a8f1