Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Herbert P, Schweizer"'
Autor:
Pacharapong Khrongsee, Jedsada Kaewrakmuk, Mariam Alami-Rose, Kuttichantran Subramaniam, Thomas B. Waltzek, Herbert P. Schweizer, Apichai Tuanyok
Publikováno v:
Frontiers in Bacteriology, Vol 3 (2024)
IntroductionBurkholderia pseudomallei, a Gram-negative bacterium inhabiting soil and fresh water, is the causative agent of melioidosis, a formidable disease in the tropics. The emergence of antibiotic resistance and the extended duration of treatmen
Externí odkaz:
https://doaj.org/article/cc9fc4af94ca4cdbb6131cd04e2f1bbe
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT In vitro activities of delafloxacin and ciprofloxacin were evaluated against Burkholderia pseudomallei mutants expressing or lacking defined resistance-nodulation-cell division (RND) efflux pumps using CLSI methodology at pHs of 5.8 and 7.2.
Externí odkaz:
https://doaj.org/article/822108ca56e34ffb9da34ca52f7cd013
Autor:
Yun Heacock-Kang, Ian A. McMillan, Michael H. Norris, Zhenxin Sun, Jan Zarzycki-Siek, Andrew P. Bluhm, Darlene Cabanas, Robert E. Norton, Natkunam Ketheesan, Jeff F. Miller, Herbert P. Schweizer, Tung T. Hoang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Prokaryotic cell transcriptomics has been limited to mixed or sub-population dynamics and individual cells within heterogeneous populations. Here the authors develop a ‘TRANSITomic’ approach to profile transcriptomes of single Burkholderia pseudo
Externí odkaz:
https://doaj.org/article/7548060208f54f84aeb09a6fe6e50257
Autor:
Brooke L. Deatherage Kaiser, Dawn N. Birdsell, Janine R. Hutchison, Johanna Thelaus, Sarah C. Jenson, Voahangy Andrianaivoarimanana, Mona Byström, Kerstin Myrtennäs, Ryelan F. McDonough, Roxanne D. Nottingham, Jason W. Sahl, Herbert P. Schweizer, Minoarisoa Rajerison, Mats Forsman, David S. Wunschel, David M. Wagner
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Antimicrobial resistance (AMR) is a well-recognized, widespread, and growing issue of concern. With increasing incidence of AMR, the ability to respond quickly to infection with or exposure to an AMR pathogen is critical. Approaches that could accura
Externí odkaz:
https://doaj.org/article/de7d79c2456a475f9f4b310531fb1f68
Autor:
Nawarat Somprasong, Carina M. Hall, Jessica R. Webb, Jason W. Sahl, David M. Wagner, Paul Keim, Bart J. Currie, Herbert P. Schweizer
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Burkholderia pseudomallei, the founding member of the B. pseudomallei complex (Bpc), is a biothreat agent and causes melioidosis, a disease whose treatment mainly relies on ceftazidime and meropenem. The concern is that B. pseudomallei could
Externí odkaz:
https://doaj.org/article/fec64c1fc3ff41d3a8385935d85b64b4
Autor:
Tae Hwan Kim, Xun Tao, Bartolome Moya, Yuanyuan Jiao, Kari B. Basso, Jieqiang Zhou, Yinzhi Lang, Dhruvitkumar S. Sutaria, Alexandre P. Zavascki, Afonso L. Barth, Stephanie M. Reeve, Herbert P. Schweizer, Deanna Deveson Lucas, John D. Boyce, Robert A. Bonomo, Richard E. Lee, Beom Soo Shin, Arnold Louie, George L. Drusano, Jürgen B. Bulitta
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Poor penetration through the outer membrane (OM) of Gram-negative bacteria is a major barrier of antibiotic development. While β-lactam antibiotics are commonly used against Klebsiella pneumoniae and Enterobacter cloacae, there are limited
Externí odkaz:
https://doaj.org/article/15920c889cbe439dba2992e6e5cf4623
Publikováno v:
BMC Microbiology, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background The work was undertaken to expand the tools available for researching Burkholderia pseudomallei (Bp), the etiological agent of the tropical disease melioidosis. Melioidosis has the potential to pose a severe threat to public healt
Externí odkaz:
https://doaj.org/article/b455bdd3305845b7a38aea3228745d51
Autor:
Carina M. Hall, Nawarat Somprasong, Johannah P. Hagen, Roxanne Nottingham, Jason W. Sahl, Jessica R. Webb, Mark Mayo, Bart J. Currie, Yuwana Podin, David M. Wagner, Paul Keim, Herbert P. Schweizer
Publikováno v:
Antimicrobial Agents and Chemotherapy.
Cefiderocol is a siderophore cephalosporin designed mainly for treatment of infections caused by β-lactam and multidrug-resistant Gram-negative bacteria. Burkholderia pseudomallei clinical isolates are usually highly cefiderocol susceptible, with in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef7459731037faf9caa38584f4f502a
https://doi.org/10.1128/aac.00171-23
https://doi.org/10.1128/aac.00171-23
Autor:
Nicole L. Podnecky, Katherine A. Rhodes, Takehiko Mima, Heather R. Drew, Sunisa Chirakul, Vanaporn Wuthiekanun, James M. Schupp, Derek S. Sarovich, Bart J. Currie, Paul Keim, Herbert P. Schweizer
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT The trimethoprim and sulfamethoxazole combination, co-trimoxazole, plays a vital role in the treatment of Burkholderia pseudomallei infections. Previous studies demonstrated that the B. pseudomallei BpeEF-OprC efflux pump confers widespread
Externí odkaz:
https://doaj.org/article/77994e52dbb14b41a3348e2f7e7f93ce
Autor:
Grace I Borlee, Brooke A Plumley, Kevin H Martin, Nawarat Somprasong, Mihnea R Mangalea, M Nurul Islam, Mary N Burtnick, Paul J Brett, Ivo Steinmetz, David P AuCoin, John T Belisle, Dean C Crick, Herbert P Schweizer, Bradley R Borlee
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005689 (2017)
Burkholderia pseudomallei, the causative agent of melioidosis, is an important public health threat due to limited therapeutic options for treatment. Efforts to improve therapeutics for B. pseudomallei infections are dependent on the need to understa
Externí odkaz:
https://doaj.org/article/a985b18871ff4468b755b783f656ed6d