Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Herbert L. de Matos Guedes"'
Autor:
Beatriz L.S. Costa Souza, Eduardo F. Pinto, Izabella P.S. Bezerra, Daniel C.O. Gomes, Ana Maria B. Martinez, Maria Inês Ré, Herbert L. de Matos Guedes, Bartira Rossi-Bergmann
Publikováno v:
Vaccine: X, Vol 15, Iss , Pp 100403- (2023)
Intranasal (i.n.) vaccination with adjuvant-free plasmid DNA encoding the leishmanial antigen LACK (LACK DNA) has shown to induce protective immunity against both cutaneous and visceral leishmaniasis in rodents. In the present work, we sought to eval
Externí odkaz:
https://doaj.org/article/1012c43ae1694fbebb4ab8d74a1ea944
Autor:
Pollyanna Stephanie Gomes, Monique Pacheco Duarte Carneiro, Patrícia de Almeida Machado, Valter Viana de Andrade-Neto, Alessandra Marcia da Fonseca-Martins, Amy Goundry, João Vitor Marques Pereira da Silva, Daniel Claudio Oliveira Gomes, Ana Paula Cabral de Araujo Lima, Vítor Ennes-Vidal, Ana Carolina Rennó Sodero, Salvatore Giovanni De-Simone, Herbert L. de Matos Guedes
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 5, Pp 2089-2106 (2022)
Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In Leishmania major and L. donovani, this enzyme has been described as essential to their survival; however, few compounds that
Externí odkaz:
https://doaj.org/article/14a0437ab2f54905977ef75da53f1211
Autor:
Ana C. Vicente Santos, Francisca H. Guedes-da-Silva, Carlos H. Dumard, Vivian N. S. Ferreira, Igor P. S. da Costa, Ruana A. Machado, Fernanda G. Q. Barros-Aragão, Rômulo L. S. Neris, Júlio S. dos-Santos, Iranaia Assunção-Miranda, Claudia P. Figueiredo, André A. Dias, Andre M. O. Gomes, Herbert L. de Matos Guedes, Andrea C. Oliveira, Jerson L. Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection usually leads to mild symptoms, but severe congenital neurological disorders and Guillain-Barré syndrome have been reported following ZIKV exposure. Crea
Externí odkaz:
https://doaj.org/article/cfd630acb424434ca57acb58b694898d
Autor:
Alessandra M. da Fonseca-Martins, Phillipe de Souza Lima-Gomes, Maísa Mota Antunes, Renan Garcia de Moura, Luciana P. Covre, Carolina Calôba, Vivian Grizente Rocha, Renata M. Pereira, Gustavo Batista Menezes, Daniel Claudio Oliveira Gomes, Elvira M. Saraiva, Herbert L. de Matos Guedes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils play an important role in the outcome of leishmaniasis, contributing either to exacerbating or controlling the progression of infection, a dual effect whose underlying mechanisms are not clear. We recently reported that CD4+ and CD8+ T ce
Externí odkaz:
https://doaj.org/article/f78158f9c28a4a92b2530888bec4bdcc
Autor:
Patrícia de A. Machado, Pollyanna S. Gomes, Monique P. D. Carneiro, Victor Midlej, Elaine S. Coimbra, Herbert L. de Matos Guedes
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1373 (2022)
Studies have previously demonstrated the importance of serine proteases in Leishmania. A well-known serine protease inhibitor, TPCK, was used in the present study to evaluate its in vitro and in vivo antileishmanial effects and determine its mechanis
Externí odkaz:
https://doaj.org/article/0557302ecb934fa391ea53ea15cf1b74
Autor:
Luciana P. Covre, Régia F. Martins, Oliver P. Devine, Emma S. Chambers, Milica Vukmanovic-Stejic, Juliana A. Silva, Reynaldo Dietze, Rodrigo R. Rodrigues, Herbert L. de Matos Guedes, Aloísio Falqueto, Arne N. Akbar, Daniel C. O. Gomes
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Leishmania (Viannia) braziliensis induces American tegumentary leishmaniasis that ranges in severity from the milder form, cutaneous (CL) to severe disseminated cutaneous leishmaniasis. Patients with CL develop a cell-mediated Th1 immune response acc
Externí odkaz:
https://doaj.org/article/1f35bdcc381541f580c4cd9e8b9f7e2f
Autor:
Bárbara José Antunes Baptista, Alessandra Granato, Fábio B. Canto, Fabricio Montalvão, Lucas Tostes, Herbert L. de Matos Guedes, Antonio Coutinho, Maria Bellio, Andre M. Vale, Alberto Nobrega
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The relative potency and quality of mouse B cell response to Toll-like receptors (TLRs) signaling varies significantly depending on the B cell subset and on the TLR member being engaged. Although it has been shown that marginal zone cells respond fas
Externí odkaz:
https://doaj.org/article/5bdbb5d9e429420bb3030ace9fb06df4
Autor:
João F. Gomes-Neto, Rossella Sartorius, Fábio B. Canto, Thamyres S. Almeida, André A. Dias, Carlos-Henrique D. Barbosa, Guilherme A. Melo, Ana Carolina Oliveira, Pedro-Henrique N. Aguiar, Carlos R. Machado, Herbert L. de Matos Guedes, Marcelo F. Santiago, Alberto Nóbrega, Piergiuseppe De Berardinis, Maria Bellio
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recombinant filamentous fd bacteriophages (rfd) expressing antigenic peptides were shown to induce cell-mediated immune responses in the absence of added adjuvant, being a promising delivery system for vaccination. Here, we tested the capacity of rfd
Externí odkaz:
https://doaj.org/article/c78c4a8f486d4d99930c762236a7c01a
Autor:
Herbert L. de Matos Guedes, Alessandra M. da Fonseca-Martins, Yuejin Liang, Eric D. Carlsen, Calvin A. Henard, Irina V. Pinchuk, Lynn Soong
Leishmania amazonensisis one of the etiological agents of diffuse cutaneous leishmaniasis in South America. In murine models of this infection, dysregulated expansion of effector T cells or exhaustion of Th1 responses are known to be related to patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eff242d8ffc14cb0a332b408e9dcef3
https://doi.org/10.1101/2022.02.15.480617
https://doi.org/10.1101/2022.02.15.480617
Autor:
Pollyanna Stephanie, Gomes, Monique Pacheco Duarte, Carneiro, Patrícia de Almeida, Machado, Valter Viana, de Andrade-Neto, Alessandra Marcia, da Fonseca-Martins, Amy, Goundry, João Vitor Marques, Pereira da Silva, Daniel Claudio Oliveira, Gomes, Ana Paula Cabral de Araujo, Lima, Vítor, Ennes-Vidal, Ana Carolina Rennó, Sodero, Salvatore Giovanni, De-Simone, Herbert L, de Matos Guedes
Publikováno v:
Current issues in molecular biology. 44(5)
Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84d77ca838864e45512a57ae76f2a993
https://pubmed.ncbi.nlm.nih.gov/35678670
https://pubmed.ncbi.nlm.nih.gov/35678670