Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Herbert Jaksche"'
Autor:
Klemens Högenauer, Niko Schmiedeberg, José M. Carballido, B. Ganesh Bhat, Luca Arista, Deborah G. Nguyen, Rochdi Bouhelal, Gudrun Werner, Herbert Jaksche, Celine Rauld, Layla Raad
Publikováno v:
Journal of medicinal chemistry. 57(24)
GPBAR1 (also known as TGR5) is a G-protein-coupled receptor (GPCR) that triggers intracellular signals upon ligation by various bile acids. The receptor has been studied mainly for its function in energy expenditure and glucose homeostasis, and there
Publikováno v:
Journal of the American Chemical Society. 118:10150-10155
A library of neomycin B mimetics has been prepared rapidly without chromatography using a neamine-derived aldehyde, tert-butyl isocyanide or isocyanoacetic acid methyl ester, a glycine-conjugated polyethylene glycol (PEG) methyl ether, and various Cb
Autor:
Greg Fisk, Amy Donner, Manfred Auer, James R. Rusche, Paul Rennert, Reed C. Doten, Thomas J. Daly, Herbert Jaksche
Publikováno v:
Biochemistry. 32:10497-10505
Recombinant HIV-1 Rev protein was overexpressed in Escherichia coli using translational coupling to the beta-glucuronidase gene and demonstrated to interact with high affinity and specificity with the Rev responsive element (RRE). A complex Rev-depen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(11)
Various proteins with different biological activities have been observed to be translocated from the nucleus to the cytoplasm in an energy- and signal-dependent manner in eukaryotic cells. This nuclear export is directed by nuclear export signals (NE
Functional Analysis of the Human Immunodeficiency Virus Type 1 Rev Protein Oligomerization Interface
Autor:
Martin Oft, Dorian Bevec, Sarah L. Thomas, Peter Heger, Herbert Jaksche, Georg Casari, Marika Dobrovnik, Joachim Hauber
The expression of human immunodeficiency virus type 1 (HIV-1) structural proteins requires the action of the viral trans -regulatory protein Rev. Rev is a nuclear shuttle protein that directly binds to its cis -acting Rev response element (RRE) RNA t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9211a74973d5a8ca72ef8ad8b0b291b8
https://europepmc.org/articles/PMC109739/
https://europepmc.org/articles/PMC109739/
Autor:
Olaf Rosorius, Octavian Schatz, Dorian Bevec, Martin Oft, Christiane Dascher, Joachim Hauber, Herbert Jaksche, Marika Dobrovnik, Michael Schebesta
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(4)
It has previously been shown that interaction of eukaryotic initiation factor 5A (eIF-5A) with the Rev trans-activator protein of HIV-1 mediates the transport of unspliced or incompletely spliced viral mRNAs across the nuclear envelope. Consequently,
Autor:
Karl Koettnitz, Michèle Himmelspach, Friedrich Lottspeich, Martin Oft, Marika Dobrovnik, Michael Schebesta, Alexandra Pacher, Herbert Jaksche, Joachim Hauber, Dorian Bevec, Robert Csonga, Thorsten Wöhl
Publikováno v:
Science (New York, N.Y.). 271(5257)
Eukaryotic initiation factor 5A (eIF-5A) is a cellular cofactor required for the function of the human immunodeficiency virus type-1 (HIV-1) Rev trans-activator protein. The majority of a set of eIF-5A mutants did not support growth of yeast cells ha
Autor:
Alexander Steinkasserer, Robert Csonga, Dorian Bevec, Barbara Kappel, Joachim Hauber, Hannelore Klier, Herbert Jaksche
Publikováno v:
FEBS letters. 378(2)
Deoxyhypusine synthase is essentially required for the post-translational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A, which appears to be pivotal for cell proliferation. From a human peripher
Escherichia coli enterotoxin: purification, partial characterization, and immunological observations
Publikováno v:
The Journal of infectious diseases.
Enterotoxin, a diarrhea-inducing protein elaborated by pathogenic Escherichia coli strains, was isolated from the supernate of fermenter cultures of E. coli strain P263, a porcine enteropathogen. Purification involved chromatography and preparative i
Publikováno v:
The Lancet. 311:718-719