Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Herbert J. Zeh, III"'
Autor:
Xinxin Song, Jiao Liu, Feimei Kuang, Xin Chen, Herbert J. Zeh, III, Rui Kang, Guido Kroemer, Yangchun Xie, Daolin Tang
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108767- (2021)
Summary: Although induction of ferroptosis, an iron-dependent form of non-apoptotic cell death, has emerged as an anticancer strategy, the metabolic basis of ferroptotic death remains poorly elucidated. Here, we show that glucose determines the sensi
Externí odkaz:
https://doaj.org/article/2275ec8fa8824df9918532d28b450b92
Autor:
Zong Sheng Guo, Zuqiang Liu, Magesh Sathaiah, Jiahu Wang, Roshni Ravindranathan, Eun Kim, Shaohua Huang, Thomas W. Kenniston, John C. Bell, Herbert J. Zeh, III, Lisa H. Butterfield, Andrea Gambotto, David L. Bartlett
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 7, Iss C, Pp 112-122 (2017)
Recombinant poxviruses, utilized as vaccine vectors and oncolytic viruses, often require manipulation at multiple genetic loci in the viral genome. It is essential for viral vectors to possess no adventitious mutations and no (antibiotic) selection m
Externí odkaz:
https://doaj.org/article/05ef89663b524fc8a998300b00359fe8
Autor:
Yangchun Xie, Shan Zhu, Xinxin Song, Xiaofang Sun, Yong Fan, Jinbao Liu, Meizuo Zhong, Hua Yuan, Lin Zhang, Timothy R. Billiar, Michael T. Lotze, Herbert J. Zeh, III, Rui Kang, Guido Kroemer, Daolin Tang
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1692-1704 (2017)
Ferroptosis is a form of regulated cell death that may facilitate the selective elimination of tumor cells. The tumor suppressor p53 (TP53) has been demonstrated to promote ferroptosis via a transcription-dependent mechanism. Here, we show that TP53
Externí odkaz:
https://doaj.org/article/e91d6a92b2b848d9862c776e96f1abd8
Autor:
John D. Karalis, Lynn Y. Yoon, Suntrea T. G. Hammer, Changjin Hong, Min Zhu, Ibrahim Nassour, Michelle R. Ju, Shu Xiao, Esther C. Castro‑Dubon, Deepak Agrawal, Jorge Suarez, Scott I. Reznik, John C. Mansour, Patricio M. Polanco, Adam C. Yopp, Herbert J. Zeh III, Tae Hyun Hwang, Hao Zhu, Matthew R. Porembka, Sam C. Wang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/30bed287feca45c48752907a4b89cd52
Autor:
Pranav Murthy, Aatur D. Singhi, Mark A. Ross, Patricia Loughran, Pedram Paragomi, Georgios I. Papachristou, David C. Whitcomb, Amer H. Zureikat, Michael T. Lotze, Herbert J. Zeh III, Brian A. Boone
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Neutrophil extracellular traps (NETs) are generated when activated neutrophils, driven by PAD4, release their DNA, histones, HMGB1, and other intracellular granule components. NETs play a role in acute pancreatitis, worsening pancreatic i
Externí odkaz:
https://doaj.org/article/2f246b1f618e4df2a01e34b810a99c8b
Autor:
Amit Raina, Alyssa M. Krasinskas, Julia B. Greer, Janette Lamb, Erin Fink, A. James Moser, Herbert J. Zeh III, Adam Slivka, David C. Whitcomb
Publikováno v:
Archives of pathologylaboratory medicine. 132(1)
Context.—Autoimmune pancreatitis is an uncommon, inflammatory disease of the pancreas that presents with clinical features, such as painless jaundice and a pancreatic mass, similar to those caused by pancreatic cancer. Patients with autoimmune panc
Autor:
William L Bigbee, Milos Hauskrecht, Herbert J Zeh III, David C Whitcomb, David E Malehorn, James Lyons-Weiler, Richard Pelikan
Publikováno v:
Cancer Informatics, Vol 1 (2005)
Cancer Informatics, Vol 1, Pp 53-77 (2005)
Cancer Informatics, Vol 1, Pp 53-77 (2005)
Peptide profiles generated using SELDI/MALDI time of flight mass spectrometry provide a promising source of patient-specific information with high potential impact on the early detection and classification of cancer and other diseases. The new profil
Autor:
Samer S. AlMasri, Mazen S. Zenati, Annissa Desilva, Ibrahim Nassour, Brian A. Boone, Aatur D. Singhi, David L. Bartlett, Lance A. Liotta, Virginia Espina, Patricia Loughran, Michael T. Lotze, Alessandro Paniccia, Herbert J. Zeh III, Amer H. Zureikat, Nathan Bahary
Publikováno v:
Cancer Medicine, Vol 10, Iss 20, Pp 7233-7241 (2021)
Abstract Introduction Preoperative autophagy inhibition with hydroxychloroquine (HCQ) in combination with gemcitabine in pancreatic adenocarcinoma (PDAC) has been shown to be safe and effective in inducing a serum biomarker response and increase rese
Externí odkaz:
https://doaj.org/article/22bcc880a5264081a326a90968f1c5d6