Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Herbert I. Jacobson"'
Autor:
Thomas T. Andersen, James A. Bennett, Kelvin E. Turner, Amithi Narendran, Anu Agarwal, Nicole Lemanski, Herbert I. Jacobson
Related Articles from A Proposed Unified Mechanism for the Reduction of Human Breast Cancer Risk by the Hormones of Pregnancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d674060ba24a6237b850c75a58865ec0
https://doi.org/10.1158/1940-6207.22523143.v1
https://doi.org/10.1158/1940-6207.22523143.v1
Autor:
Thomas T. Andersen, James A. Bennett, Kelvin E. Turner, Amithi Narendran, Anu Agarwal, Nicole Lemanski, Herbert I. Jacobson
Parity in women is associated with reduced lifetime risk of breast cancer, and hormones of pregnancy [estrogen (E), progesterone (P), human chorionic gonadotropin (hCG)] are implicated. Parity also reduces mammary cancer risk in carcinogen-exposed ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fba5245555b23e68fa660d7c7fd2030
https://doi.org/10.1158/1940-6207.c.6543610.v1
https://doi.org/10.1158/1940-6207.c.6543610.v1
Publikováno v:
Perspectives in Biology and Medicine; January 1963, Vol. 6 Issue: 3 p383-385, 3p
Autor:
H. A. Krebs
Publikováno v:
Perspectives in Biology and Medicine. 6:383-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee48ac84b21809dd9aeb2ccb30873e1b
https://doi.org/10.1353/pbm.1963.0051
https://doi.org/10.1353/pbm.1963.0051
Publikováno v:
Cancer Prevention Research. 7:565-573
Epidemiologic studies associate elevated maternal serum levels of α-fetoprotein (AFP) with reduced breast cancer risk for parous women. Laboratory studies demonstrate direct anti-breast cancer activity of AFP. Here, we review the development of a sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc76f051e6f4c0c3c1aef26ce28f54ea
https://doi.org/10.1158/1940-6207.capr-13-0405
https://doi.org/10.1158/1940-6207.capr-13-0405
Publikováno v:
Peptides. 32:2504-2510
In earlier work, we synthesized a cyclic 9-amino acid peptide (AFPep, cyclo[EKTOVNOGN]) and showed it to be useful for prevention and therapy of breast cancer. In an effort to explore the structure-function relationships of AFPep, we have designed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1991ee62b3e4648d7b9d0b0215a999f
https://doi.org/10.1016/j.peptides.2011.10.007
https://doi.org/10.1016/j.peptides.2011.10.007
Autor:
John Hughes, Herbert I. Jacobson, Karl N. Kirschner, Leroy C. Joseph, James A. Bennett, George C. Shields, Nicole Lostritto, Thomas T. Andersen
Publikováno v:
Journal of Peptide Science. 15:319-325
Cyclo[EKTOVNOGN] (AFPep), a cyclic 9-amino acid peptide derived from the active site of alpha-fetoprotein, has been shown to prevent carcinogen-induced mammary cancer in rats and inhibit the growth of ER(+) human breast cancer xenografts in mice. Rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883cc6ad2fa665db1b7fe6ffe691546a
https://doi.org/10.1002/psc.1119
https://doi.org/10.1002/psc.1119
Autor:
James A. Bennett, Nicole Lemanski, Amithi Narendran, Thomas T. Andersen, J Georgekutty, Lori DeFreest, G Amaratunga, Herbert I. Jacobson
Publikováno v:
British Journal of Cancer
Tamoxifen (Tam) is effective for the treatment and prevention of breast cancer. However, it has toxic drawbacks and has limited-duration utility because, over time, human tumours become refractory to Tam. Recently, a new nontoxic peptide, alpha-fetop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8897e86e19f0d6d9d6996c790a1031
http://europepmc.org/articles/PMC2360332
http://europepmc.org/articles/PMC2360332
Autor:
Katrina W. Lexa, Leroy C. Joseph, Katherine A. Alser, James A. Bennett, Herbert I. Jacobson, Amanda M. Salisburg, George C. Shields, Karl N. Kirschner, Thomas T. Andersen
Publikováno v:
Journal of the American Chemical Society. 129:6263-6268
Breast cancer is the most common cancer among women, and tamoxifen is the preferred drug for estrogen receptor-positive breast cancer treatment. Many of these cancers are intrinsically resistant to tamoxifen or acquire resistance during treatment. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd721fd6e11b0eca40eaff406b754e65
https://doi.org/10.1021/ja070202w
https://doi.org/10.1021/ja070202w
Autor:
James A. Bennett, Hamid Saadati, Lori DeFreest, Herbert I. Jacobson, Sujata Balulad, Ikenna Anaka, Thomas T. Andersen
Publikováno v:
Breast Cancer Research and Treatment. 98:133-141
We have synthesized a cyclic nonapeptide (AFPep) that is effective, after being administered by parenteral routes, for the treatment or the prevention of breast cancer. To test the hypothesis that AFPep remains safe and efficacious after oral adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7763a17905481225f1bcd153c276eb
https://doi.org/10.1007/s10549-005-9140-5
https://doi.org/10.1007/s10549-005-9140-5