Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Herbert D. Soule"'
Autor:
Anwar N. Mohamed, Herbert D. Soule, Fred R. Miller, James Eliason, Larry Tait, Peter J. Dawson, Steven J. Santner, Gloria H. Heppner, Sandra R. Wolman
Publikováno v:
Breast Cancer Research and Treatment. 65:101-110
The MCF10 series of cell lines was derived from benign breast tissue from a woman with fibrocystic disease. The MCF10 human breast epithelial model system consists of mortal MCF10M and MCF10MS (mortal cells grown in serum-free and serum-containing me
Autor:
James K V Willson, Yong Ko, Wenhui Li, Elizabeth Zborowska, Herbert D. Soule, Sunandita S. Banerji, Robert J. Pauley, Yu Liu, Michael G. Brattain, Jiurong Liang
Publikováno v:
Journal of Cellular Physiology. 176:424-434
To analyze transforming growth factor-beta (TGF-beta) response during MCF-7 cell progression, early passage (MCF-7E, 500 passage) cells were compared. MCF-7E cells showed an IC50 of approximately 10 ng/ml of TGF-beta1, whereas MCF-7L cells were insen
Autor:
Robert J. Pauley, Gloria H. Heppner, Larty Tait, Fred R. Miller, Sandra R. Wolman, Herbert D. Soule, Peter J. Dawson
Publikováno v:
JNCI Journal of the National Cancer Institute. 85:1725-1732
Background Progression of proliferative breast disease has been associated with increased risk for development of invasive carcinoma. Cell lines have been developed to facilitate the study of this process. Human cell line MCF10A originated from spont
Publikováno v:
International Journal of Cancer. 50:463-473
We have previously described the mortal human breast epithelial culture MCF-10M, that was derived from fibrocystic breast tissue, was cultivated in medium with low calcium content for over 2 years, and spontaneously gave rise to the immortal MCF-10 c
Autor:
W. P. Shi, Wei-Zen Wei, Jose Russo, Gloria M. Calaf, Herbert D. Soule, R. Pauley, Richard F. Jones, D. Lichlyter
Publikováno v:
British Journal of Cancer
Molecular changes associated with breast cancer progression were characterized using the MCF-10F cell series. MCF-10F was established from fibrous mastectomy tissue of a patient without detectable cancer. In vitro treatment of MCF-10F cells with benz
Publikováno v:
Genes, chromosomescancer. 10(1)
We describe a series of five immortal breast cell lines that have emerged independently from diploid cultures from two individuals. We have karyotyped representative cultures of each of these lines prior to and at intervals after immortalization. Alt
Autor:
Charles M. McGrath, Herbert D. Soule
Publikováno v:
Cancer Letters. 10:177-189
A clone of MCF-7 (MCF-7ED), a cell in continuous in vitro cultivation derived from an estrogen-responsive human breast carcinoma, requires estrogen supplementation for progressive exponential (doubling time: 50–85 h) tumor growth in the mammary fat
Autor:
Herbert D. Soule, Charles M. McGrath
Publikováno v:
Journal of Cellular Physiology. 116:385-396
Cortisol and insulin stimulated exponential growth of normal human mammary epithelium in short-term monolayer culture. The response of cells depended on their organization into "growth units" on the surface of the culture dish; single cells did not r
Publikováno v:
Nature. 252:247-250
THE search for RNA-containing human breast cancer viruses has been helped by the discovery of several biochemical and biophysical characteristics of the oncornavirus group1–4. Although these properties may not be unique to oncornaviruses5, they pro
Publikováno v:
In Vitro. 12:57-64
A fine structural study was made of cells from the epithelioid MCF-8/5-2A cell line derived from a MuMTV-free D2 transplantable hyperplastic outgrowth. Electron microscopy shows the cells to be truly epithelial with many cell-to-cell junctions and mi