Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Herbert Bosshardt"'
Publikováno v:
Journal of Pharmaceutical Sciences. 83:131-136
The dissolution rate profile of a new modified-release (MR) oral tablet of ketotifen (Zaditen SRO tablet, Sandoz Ltd.) was determined under different conditions (pH, rpm, paddle or basket) with the U.S.P. apparatus. Three different variants of MR tab
Autor:
Herbert Bosshardt, Manfred Hesse
Publikováno v:
Angewandte Chemie International Edition in English. 13:252-266
The mass spectral decomposition of di- and polyfunctional alkanes is characterized essentially by two, fundamentally different reactions: On the one hand the structures of the fragment ions are determined by separated degradation of each functional g
Publikováno v:
Helvetica Chimica Acta. 62:2712-2723
Contribution to the Absolute Configuration of the Spermine Alkaloids O-Methylorantine and Aphelandrine The absolute configuration of the spermine alkaloid O-methylorantine (1) isolated from Chaenorhinum minus (L.) WILLK. ET LGE. and Ch. villosum (L.)
Autor:
Manfred Hesse, Herbert Bosshardt
Publikováno v:
Angewandte Chemie. 86:256-270
Publikováno v:
Helvetica Chimica Acta. 61:2646-2671
The structure of the spermine alkaloid aphelandrine from Aphelandra squarrosa NEES The new spermine alkaloid aphelandrine (2) has been isolated from Aphelandra squarrosa NEES. By oxidation of 2 with KMnO4 followed by methylation (CH2N2) 12 and 14 cou
Autor:
Rattan S. Sood, Fathy S. Matough, James P. Kutney, Brian R. Worth, Vicente E. Ridaura-Sanz, Ying Hung So, John F. Beck, Rodney A. Badger, Herbert Bosshardt
Publikováno v:
Canadian Journal of Chemistry. 57:289-299
A synthesis of 16,17-dihydrosecodin-17-ol and of secodine is described. Various indole derivatives were elaborated to a series of pyridinium salts, potential precursors for 1,2- and 1,6-dihydropyridine compounds exemplifying the proposed biointermedi
Publikováno v:
Chemischer Informationsdienst. 10
Autor:
Manfred Hesse, Herbert Bosshardt
Publikováno v:
Chemischer Informationsdienst. 5
Publikováno v:
Chemischer Informationsdienst. 11
A Facile Route to a Sensitive Terpene Alcohol—Regio-unselective Metalation ofα-Terpinene as Key Step
Publikováno v:
Angewandte Chemie International Edition in English. 19:303-303
Treatment of a-terpinene (I, R = H) with BuLi-KOCMe3 followed by FB(OMe)2 and then alk. H2O2 soln. gave 44% anthemol (I, R = OH). The metalation step of a-terpinene presumably gave 3 pentadiene-K species (II-IV), which reacted with D2O and ClSiMe3 to