The Uso1 globular head interacts with SNAREs to maintain viability even in the absence of the coiled-coil domain

Autor: Ignacio Bravo-Plaza, Victor G Tagua, Herbert N Arst, Ana Alonso, Mario Pinar, Begoña Monterroso, Antonio Galindo, Miguel A Peñalva

Publikováno v: eLife, Vol 12 (2023)

Uso1/p115 and RAB1 tether ER-derived vesicles to the Golgi. Uso1/p115 contains a globular-head-domain (GHD), a coiled-coil (CC) mediating dimerization/tethering, and a C-terminal region (CTR) interacting with golgins. Uso1/p115 is recruited to vesicl

Externí odkaz: https://doaj.org/article/23dcb24258ac4c1cbe62297220a22def

Endocytic recycling via the TGN underlies the polarized hyphal mode of life.

Autor: Miguel Hernández-González, Ignacio Bravo-Plaza, Mario Pinar, Vivian de Los Ríos, Herbert N Arst, Miguel A Peñalva

Publikováno v: PLoS Genetics, Vol 14, Iss 4, p e1007291 (2018)

Intracellular traffic in Aspergillus nidulans hyphae must cope with the challenges that the high rates of apical extension (1μm/min) and the long intracellular distances (>100 μm) impose. Understanding the ways in which the hyphal tip cell coordina

Externí odkaz: https://doaj.org/article/a57753ce55b14dad947071a70ff14c17

Proteolytic activation of both components of the cation stress–responsive Slt pathway in Aspergillus nidulans

Autor: Eduardo A. Espeso, Herbert N. Arst, Laura Mellado

Publikováno v: Molecular Biology of the Cell
Digital.CSIC. Repositorio Institucional del CSIC
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15 p.-11 fig.
Tolerance of Aspergillus nidulans to alkalinity and elevated cation concentrations requires both SltA and SltB. Transcription factor SltA and the putative pseudokinase/protease signaling protein SltB comprise a regulatory pathway s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d8ef760e6a1b20cf3b3d473f80eaa6
http://europepmc.org/articles/PMC4985261

Refining the pH response in A spergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein

Autor: Herbert N. Arst, Lynne Rainbow, Maria M Peñas-Parilla, Henk-Jan Bussink, Elaine Bignell, Daniel Lucena-Agell, Eduardo A. Espeso, Susana Negrete-Urtasun, Joanna D. Rudnicka, Claudio Scazzocchio, Miguel A. Peñalva, Joan Tilburn, Tatiana Múnera-Huertas, Margherita Bertuzzi

Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 2015, 98 (6), pp.1051-72. ⟨10.1111/mmi.13173⟩
Molecular Microbiology, 2015, 98 (6), pp.1051-72. ⟨10.1111/mmi.13173⟩
Molecular Microbiology, Wiley, 2015, 98 (6), pp.1051-72. 〈10.1111/mmi.13173〉

International audience; The Aspergillus nidulans PacC transcription factor mediates gene regulation in response to alkaline ambient pH which, signalled by the Pal pathway, results in the processing of PacC(72) to PacC(27) via PacC(53). Here we invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e459377aebf1eecce959bf04a352b2
http://europepmc.org/articles/PMC4832277

Genetic studies on the physiological role of CORVET in Aspergillus nidulans

Autor: Mario Pinar, Miguel A. Peñalva, Herbert N. Arst, Manuel S. López‐Berges

Publikováno v: FEMS Microbiology Letters. 364

CORVET and HOPS are protein complexes mediating the maturation of early endosomes (EEs) into late endosomes (LEs)/vacuoles. These hetero-hexamers share four 'core' components, Vps11, Vps16, Vps18 and Vps33, and differ in two specific subunits, CORVET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48b8af6efb039cbdb5ccc45337be8dc
https://doi.org/10.1093/femsle/fnx065