Zobrazeno 1 - 10
of 549
pro vyhledávání: '"Herbert, Schwarz"'
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 11, Pp 2387-2388 (2023)
Externí odkaz:
https://doaj.org/article/72f7578afbbf4d20b4bc53dee344c63b
Autor:
Heng Boon Low, Zhen Lim Wong, Bangyuan Wu, Li Ren Kong, Chin Wen Png, Yik-Lam Cho, Chun-Wei Li, Fengchun Xiao, Xuan Xin, Henry Yang, Jia Min Loo, Fiona Yi Xin Lee, Iain Bee Huat Tan, Ramanuj DasGupta, Han-Ming Shen, Herbert Schwarz, Nicholas R. J. Gascoigne, Boon Cher Goh, Xiaohong Xu, Yongliang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Chemoresistance is one of the main challenges for cancer therapy success. Here, the authors show that dual-specificity phosphatase 16 (DUSP16) expression is associated with chemoresistance in several types of cancer through impairing mitochondria-ass
Externí odkaz:
https://doaj.org/article/7cd1e1ed821d475f86d18b8927eabe0d
Autor:
Huizhi Chen, Liyan Wang, Xinling Zeng, Herbert Schwarz, Himansu Sekhar Nanda, Xinsheng Peng, Yubin Zhou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing numerous biological molecules including nucleic acids, proteins and lipids, which are thought to play important roles in intercellular communication. As carriers,
Externí odkaz:
https://doaj.org/article/e717e2f26ab74284a7e0f9ebf9ac71dc
Autor:
Rui Sun, Jia Le Lin, Man Si Cheng, Kang Yi Lee, Thilo Spruss, Christa Buechler, Herbert Schwarz
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2610 (2022)
Chemerin is a multifunctional adipokine that regulates adipogenesis, insulin signaling and blood pressure and has thus a central function in metabolism. Mounting evidence confirmed a function of chemerin in various cancers. In this study, we investig
Externí odkaz:
https://doaj.org/article/2e4fb153e9b047eda8db5689340c9340
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The discovery of immune checkpoints highlights the complexity of T cell signalling during an immune response. Upon activation, T cells express several molecules to regulate their function and to prevent overactivation. B7 homolog 7 (B7-H7) is express
Externí odkaz:
https://doaj.org/article/96c5e77c21724a3abf98fcda50ccb7a8
Autor:
Kang Yi Lee, Hiu Yi Wong, Qun Zeng, Jia Le Lin, Man Si Cheng, Chik Hong Kuick, Kenneth Tou En Chang, Amos Hong Pheng Loh, Herbert Schwarz
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Rhabdomyosarcoma (RMS) is a heterogeneous soft tissue neoplasm most frequently found in children and adolescents. As the prognosis for recurrent and metastatic RMS remains poor, immunotherapies are hoped to improve quality of life and survival. CD137
Externí odkaz:
https://doaj.org/article/fecc1db05df049e5b7d9e2a1cbcdad2f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The potent costimulatory effect of CD137 has been implicated in several murine autoimmune disease models. CD137 costimulates and polarizes antigen-specific T cells toward a potent Th1/Tc1 response, and is essential for the development of experimental
Externí odkaz:
https://doaj.org/article/bf106b120ff146718c73bbef7ecf1d7f
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
New evidence indicates the importance of CD137 for controlling Epstein-Barr virus (EBV) infections. (1) Mutations in CD137 predispose to EBV-associated diseases. (2) EBV induces ectopic CD137 expression, thereby activating a negative feed-back regula
Externí odkaz:
https://doaj.org/article/95d98c18ed0e43af9106c937aaf0471e
Autor:
Qun Zeng, Herbert Schwarz
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Hodgkin lymphoma (HL) is a unique type of hematopoietic cancer that has few tumor cells but a massive infiltration of immune cells. Findings on how the cancerous Hodgkin and Reed-Sternberg (HRS) cells survive and evade immune surveillance have facili
Externí odkaz:
https://doaj.org/article/c2d536db6b494679a4aea95dacc35cc6
Autor:
Samantha K. Ong, Syeda F. Husain, Hai Ning Wee, Jianhong Ching, Jean-Paul Kovalik, Man Si Cheng, Herbert Schwarz, Tong Boon Tang, Cyrus S. Ho
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 1978 (2021)
Background: Major depressive disorder (MDD) is a debilitating condition with a high disease burden and medical comorbidities. There are currently few to no validated biomarkers to guide the diagnosis and treatment of MDD. In the present study, we eva
Externí odkaz:
https://doaj.org/article/7236e792ea29465695e8819034078325