Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Herbert, Kuster"'
Autor:
Yik Lim Kok, Valentina Vongrad, Sandra E. Chaudron, Mohaned Shilaih, Christine Leemann, Kathrin Neumann, Katharina Kusejko, Francesca Di Giallonardo, Herbert Kuster, Dominique L. Braun, Roger D. Kouyos, Huldrych F. Günthard, Karin J. Metzner
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
HIV-1 is capable of integrating its genome into that of its host cell. We examined the influence of the activation state of CD4+ T cells, the effect of antiretroviral therapy (ART), and the clinical stage of HIV-1 infection on HIV-1 integration site
Externí odkaz:
https://doaj.org/article/75947c53605647039e34b1ef5eb63e40
Autor:
David Seifert, Beda Joos, Dominique L. Braun, Corinna S. Oberle, Corinne D. Schenkel, Herbert Kuster, Christina Grube, Jürg Böni, Sabine Yerly, Vincent Aubert, Thomas Klimkait, Huldrych F. Günthard, Niko Beerenwinkel, Karin J. Metzner, on behalf of the Swiss HIV Cohort Study
Publikováno v:
Viruses, Vol 14, Iss 2, p 406 (2022)
Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles
Externí odkaz:
https://doaj.org/article/a2d2a2e73e1c475f92e18d04fcf25821
Autor:
Audrey E. Rindler, Herbert Kuster, Kathrin Neumann, Christine Leemann, Dominique L. Braun, Karin J. Metzner, Huldrych F. Günthard
Publikováno v:
Viruses, Vol 13, Iss 3, p 404 (2021)
HIV-1 replication capacity is an important characteristic to understand the replication competence of single variants or virus populations. It can further aid in the understanding of HIV-1 pathogenicity, disease progression, and drug resistance mutat
Externí odkaz:
https://doaj.org/article/3d484e9b79d34979b47a9d6d1db4d2fa
Autor:
Study, David Seifert, Beda Joos, Dominique L. Braun, Corinna S. Oberle, Corinne D. Schenkel, Herbert Kuster, Christina Grube, Jürg Böni, Sabine Yerly, Vincent Aubert, Thomas Klimkait, Huldrych F. Günthard, Niko Beerenwinkel, Karin J. Metzner, on behalf of the Swiss HIV Cohort Study on behalf of the Swiss HIV Cohort
Publikováno v:
Viruses; Volume 14; Issue 2; Pages: 406
Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles
Autor:
Audrey E Rindler, Katharina Kusejko, Herbert Kuster, Kathrin Neumann, Christine Leemann, Marius Zeeb, Sandra E Chaudron, Dominique L Braun, Roger D Kouyos, Karin J Metzner, Huldrych F Günthard
Publikováno v:
The Journal of infectious diseases. 226(6)
Background HIV-1 replication capacity (RC) of transmitted/founder viruses may influence the further course of HIV-1 infection. Methods RCs of 355 whole-genome primary HIV-1 isolates derived from samples acquired during acute and recent primary HIV-1
Autor:
David, Seifert, Beda, Joos, Dominique L, Braun, Corinna S, Oberle, Corinne D, Schenkel, Herbert, Kuster, Christina, Grube, Jürg, Böni, Sabine, Yerly, Vincent, Aubert, Thomas, Klimkait, Huldrych F, Günthard, Niko, Beerenwinkel, Karin J, Metzner, On Behalf Of The Swiss Hiv Cohort Study
Publikováno v:
Viruses. 14(2)
Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles
Autor:
Claus Kadelka, Huldrych F. Günthard, Herbert Kuster, Melissa Robbiani, Dominique L Braun, Thomas Liechti, Alexandra Trkola, Jürg Böni
Publikováno v:
The Journal of Experimental Medicine
Liechti et al. demonstrate severe B cell perturbations in HIV-1 infection beyond described effects on memory B cells. Naive and marginal zone B cells down-regulate CD21 and display chemokine receptor and activation marker signatures associated with i
Autor:
Dominique L Braun, Roger Kouyos, Corinna Oberle, Christina Grube, Beda Joos, Jacques Fellay, Paul J McLaren, Herbert Kuster, Huldrych F Günthard
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114111 (2014)
Best long-term practice in primary HIV-1 infection (PHI) remains unknown for the individual. A risk-based scoring system associated with surrogate markers of HIV-1 disease progression could be helpful to stratify patients with PHI at highest risk for
Externí odkaz:
https://doaj.org/article/d98d8af9798b4fd291b9c7179236333d
Autor:
Craig S. Pace, Romas Geleziunas, Mini Balakrishnan, Aiyappa Parvangada, Dominique L Braun, Nathan D. Thomsen, Huldrych F. Günthard, Herbert Kuster, Brian Moldt, Christian Callebaut, Sean E Collins, Ross Martin
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 88(1)
BACKGROUND HIV envelope (env) diversity represents a significant challenge for the use of broadly neutralizing antibodies (bNAbs) in HIV treatment and cure studies. Screening for viral sensitivity to bNAbs to select eligible trial participants will b
Autor:
Claus Kadelka, Christine Leemann, Karin J. Metzner, Merle Schanz, Michael Huber, Alexandra U. Scherrer, Alex Marzel, Nikolas Friedrich, Dominique L Braun, Therese Uhr, Baumann Ns, Enos Bernasconi, Aubert, Andri Rauch, Matthias Cavassini, Hanna Ebner, Alexandra Trkola, Matthias Hoffmann, Thomas Klimkait, Sabine Yerly, Manuel Battegay, Roger D. Kouyos, Jürg Böni, Alexandra Calmy, Jacqueline Weber, J. P. Chave, Huldrych F. Günthard, Herbert Kuster, Thomas Liechti, Peter Rusert
Publikováno v:
Nature. 561:406-410
Understanding the determinants of broadly neutralizing antibody (bNAb) evolution is crucial for the development of bNAb-based HIV vaccines. Despite emerging information on cofactors that promote bNAb evolution in natural HIV-1 infections, in which th