Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Herbert, Kim Lyerly"'
Autor:
Xiao Yang, Michael A Morse, Takuya Osada, Amy Hobeika, Herbert Kim Lyerly, Zachary Conrad Hartman, Hiroshi Nagata, Kensuke Kaneko, Chaitanya R Acharya, Philip F Hughes, Timothy A J Haystead
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background We previously demonstrated potent antitumor activity against human breast cancer xenografts using photodynamic therapy (PDT) targeting a novel tumor-specific photosensitizer (HS201), which binds heat shock protein 90 (HS201-PDT). However,
Externí odkaz:
https://doaj.org/article/565e94da5b9048f6b975c2f576e21cce
Autor:
Darya Kizub, Cathyryne K. Manner, Katy Graef, Bello Abubakar, Jackson Orem, Folakemi Odedina, Mojisola Christianah Adeyeye, Gertrude Nakigudde, Kassa Ayalew, Chitkala Kalidas, Herbert Kim Lyerly, Thea Norman, Lola Fashoyin-Aje, Jamie Freedman, Jennifer Dent, Bill Cance, Julie Gralow
Publikováno v:
JCO Global Oncology, Vol , Iss 8 (2022)
Patients of African ancestry are not well-represented in cancer clinical trials despite bearing a disproportionate share of mortality both in United States and Africa. We describe key stakeholder perspectives and priorities related to bringing early-
Externí odkaz:
https://doaj.org/article/c70bdb1e2e38445683572079d0ce2509
Autor:
Li-Chung Tsao, Erika J. Crosby, Timothy N. Trotter, Junping Wei, Tao Wang, Xiao Yang, Amanda N. Summers, Gangjun Lei, Christopher A. Rabiola, Lewis A. Chodosh, William J. Muller, Herbert Kim Lyerly, Zachary C. Hartman
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
Two HER2-specific mAbs, trastuzumab and pertuzumab (T+P), combined with chemotherapy comprise standard-of-care treatment for advanced HER2+ breast cancers (BC). While this antibody combination is highly effective, its synergistic mechanism-of-action
Externí odkaz:
https://doaj.org/article/c87d5137315e42528a934056270a6891
Autor:
Tao Wang, Michael A Morse, Takuya Osada, Herbert Kim Lyerly, Junping Wei, Xiao-Yi Yang, Gangjun Lei, Zachary Conrad Hartman, Pankaj Agarwal, Li-Chung Tsao, Chaitanya R Acharya, Bin-Jin Hwang, Timothy Trotter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background The majority of colorectal carcinomas (CRCs) are insensitive to programmed death protein-1/programmed death-ligand 1 (anti-PD-1/PD-L1) immune checkpoint inhibitor (ICI) antibodies. While there are many causes for ICI insensitivity, recent
Externí odkaz:
https://doaj.org/article/7313de08ca68445aa4436a03e31eed63
Autor:
Xiao Yang, Tao Wang, Michael A Morse, Takuya Osada, William Gwin, Herbert Kim Lyerly, Cong-Xiao Liu, Pankaj Agarwal, Hiroshi Nagata, Erika J Crosby, Pei Zhong, Shinya Abe, Yoshiyuki Inoue, Kensuke Kaneko, Chaitanya R Acharya, Joshua Snyder
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/f1a40627b3444ff2afb9da9c50ee6a96
Autor:
Guoliang Qiao, Xiaoli Wang, Xinna Zhou, Michael A. Morse, Jiangping Wu, Shuo Wang, Yuguang Song, Ni Jiang, Yanjie Zhao, Lei Zhou, Jing Zhao, Yan Di, Lihong Zhu, Amy Hobeika, Jun Ren, Herbert Kim Lyerly
Publikováno v:
International Journal of Hyperthermia, Vol 36, Iss 0, Pp 74-82 (2019)
Purpose: To characterize the T cell receptor (TCR) repertoire, serum cytokine levels, peripheral blood T lymphocyte populations, safety, and clinical efficacy of hyperthermia (HT) combined with autologous adoptive cell therapy (ACT) and either salvag
Externí odkaz:
https://doaj.org/article/ec37ab547cd14cb0ab40039eed9430ee
Autor:
Kensuke Kaneko, Hiroshi Nagata, Xiao-Yi Yang, Joshua Ginzel, Zachary Hartman, Jeffrey Everitt, Philip Hughes, Timothy Haystead, Michael Morse, Herbert Kim Lyerly, Takuya Osada
Publikováno v:
Cancers, Vol 14, Iss 23, p 5762 (2022)
Ductal carcinoma in situ (DCIS) of the breast is often managed by lumpectomy and radiation or mastectomy, despite its indolent features. Effective non-invasive treatment strategies could reduce the morbidity of DCIS treatment. We have exploited the h
Externí odkaz:
https://doaj.org/article/aef9105a5003436fb0c3fb2b2b03f1cc
Autor:
Duo Yang, Xiaoli Wang, Xinna Zhou, Jing Zhao, Huabing Yang, Shuo Wang, Michael A. Morse, Jiangping Wu, Yanhua Yuan, Sha Li, Amy Hobeika, Herbert Kim Lyerly, Jun Ren
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Human microbiota influence the response of malignancies to treatment with immune checkpoint blockade; however, their impact on other forms of immunotherapy is poorly understood. This study explored the effect of blood microbiota on clinical efficacy,
Externí odkaz:
https://doaj.org/article/f08c4a0a824844c3909df4d8abff9757
Autor:
Becker, Robert, Beer, Philip, Bergh, Jonas, Bogaerts, Jan, Dovedi, Simon, Fojo, Antonio T., Gerstung, Moritz, Golfinopoulos, Vassilis, Hewitt, Stephen, Hochhauser, Daniel, Juhl, Hartmut, Kinders, Robert, Lillie, Thomas, Herbert, Kim Lyerly, Maheswaran, Shyamala, Mesri, Mehdi, Nagai, Sumimasa, Norstedt, Irene, O'Connor, Daniel, Oliver, Kathy, Oyen, Wim J.G., Pignatti, Francesco, Polley, Eric, Rosenfeld, Nitzan, Schellens, Jan, Schilsky, Richard, Schneider, Erasmus, Senderowicz, Adrian, Tenhunen, Olli, van Dongen, Augustinus, Vietz, Christine, Wilking, Nils, Salgado, Roberto, Moore, Helen, Martens, John W.M., Lively, Tracy, Malik, Shakun, McDermott, Ultan, Michiels, Stefan, Moscow, Jeffrey A., Tejpar, Sabine, McKee, Tawnya, Lacombe, Denis
Publikováno v:
In European Journal of Cancer October 2017 84:325-334
Autor:
Neil S. Forbes, Robert S. Coffin, Liang Deng, Laura Evgin, Steve Fiering, Matthew Giacalone, Claudia Gravekamp, James L. Gulley, Hal Gunn, Robert M. Hoffman, Balveen Kaur, Ke Liu, Herbert Kim Lyerly, Ariel E. Marciscano, Eddie Moradian, Sheryl Ruppel, Daniel A. Saltzman, Peter J. Tattersall, Steve Thorne, Richard G. Vile, Halle Huihong Zhang, Shibin Zhou, Grant McFadden
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-24 (2018)
Abstract In this White Paper, we discuss the current state of microbial cancer therapy. This paper resulted from a meeting (‘Microbial Based Cancer Therapy’) at the US National Cancer Institute in the summer of 2017. Here, we define ‘Microbial
Externí odkaz:
https://doaj.org/article/59241f901cfc4e0f9a8a64cfde57e873