COVID-19: Immunology and treatment options

Autor: Felsenstein, Susanna, Herbert, Jenny A., McNamara, Paul S., Hedrich, Christian M.

Publikováno v: In Clinical Immunology June 2020 215

The effect of COVID-19 on our lifestyle and microbiome: What could long term imbalanced diet and germophobia mean for our immunity?

Autor: Almadhi, Marwah, Gharaei, Sophie, Herbert, Jenny A., Alkhalaf, Moustafa A., Kahlat, Karima, Yates, Carol, Panagiotou, Stavros

Publikováno v: In Hygiene and Environmental Health Advances March 2023 5

β2 integrin LFA1 mediates airway damage following neutrophil trans-epithelial migration during RSV infection

Autor: Herbert, Jenny

Publikováno v: Herbert, J 2020, ' β2 integrin LFA1 mediates airway damage following neutrophil trans-epithelial migration during RSV infection ', European Respiratory Journal . https://doi.org/10.1183/13993003.02216-2019

RSV bronchiolitis is the most common cause of infant hospital admissions, but there is limited understanding of the mechanisms of disease and no specific anti-viral treatment. Using a novel in vitro primary trans-epithelial neutrophil migration model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::953635e1582eb98db95f3bb987a2745d
https://www.research.manchester.ac.uk/portal/en/publications/2-integrin-lfa1-mediates-airway-damage-following-neutrophil-transepithelial-migration-during-rsv-infection(39817c63-8d69-4648-a0d6-31a90e3157c2).html

Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine

Autor: Herbert, Jenny A, Kay, Emily J, Faustini, Sian E, Richter, Alex, Abouelhadid, Sherif, Cuccui, Jon, Wren, Brendan, Mitchell, Timothy J

Publikováno v: Vaccine
Herbert, J A, Kay, E J, Faustini, S E, Richter, A, Abouelhadid, S, Cuccui, J, Wren, B & Mitchell, T J 2018, ' Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine ', Vaccine, vol. 36, no. 26, pp. 3809-3819 . https://doi.org/10.1016/j.vaccine.2018.05.036

Highlights • Pneumococcal glycoconjugate vaccines produced in E. coli are protective in mice. • Protection correlates with opsonic antibody levels. • This is a cheaper way to produce conjugate vaccines.
Streptococcus pneumoniae is the lead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f0e03bbf7908618b2fce21d8249560ee
http://europepmc.org/articles/PMC5999350

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