Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer’s Mouse Phenotypes

Autor: Haas, Laura T. ^{1, 2}, Salazar, Santiago V. ¹, Smith, Levi M. ¹, Zhao, Helen R. ¹, Cox, Timothy O. ¹, Herber, Charlotte S. ¹, Degnan, Andrew P. ³, Balakrishnan, Anand ³, Macor, John E. ³, Albright, Charles F. ³, Strittmatter, Stephen M. ^{1, 4, 5, ∗}

Publikováno v: In Cell Reports 5 July 2017 20(1):76-88

Spatial Coding Dysfunction and Network Instability in the Aging Medial Entorhinal Cortex.

Autor: Herber CS; Department of Neurobiology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, 94305, USA., Pratt KJB; Department of Anatomy, University of California San Francisco, 513 Parnassus Avenue, Box 0452, San Francisco, CA, 94143, USA.; These authors contributed equally., Shea JM; Department of Anatomy, University of California San Francisco, 513 Parnassus Avenue, Box 0452, San Francisco, CA, 94143, USA.; These authors contributed equally., Villeda SA; Department of Anatomy, University of California San Francisco, 513 Parnassus Avenue, Box 0452, San Francisco, CA, 94143, USA.; Bakar Aging Research Institute, San Francisco, CA, 94143, USA., Giocomo LM; Department of Neurobiology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, 94305, USA.; Lead contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 17. Date of Electronic Publication: 2024 Apr 17.