P-Cadherin (CDH3) is overexpressed in colorectal tumors and has potential as a serum marker for colorectal cancer monitoring

Autor: Kumara Hmcs, Geoffrey Bellini, Caballero Ol, Richard L. Whelan, Aqeel Ahmed, Herath Sac, Tao Su, Cekic, Linda Njoh

Publikováno v: Oncoscience

Introduction Placental-Cadherin (CDH3) is a cell adhesion molecule vital to cellular localization and tissue integrity. It is highly expressed in the placenta (PLC)and is overexpressed by many types of cancer. P-cadherin levels in colorectal cancer (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b69dcb8eaad6d0e86eb03a70f4719ec
http://europepmc.org/articles/PMC5672898

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy.

Autor: Kumara HMCS; Division of Colon and Rectal Surgery, Department of Surgery, Lenox Hill Hospital, Northwell Health, New York, NY 10028, USA., Sutton E; Department of Surgery, Mount Sinai West Hospital, New York, NY 10019, USA., Caballero OL; Ludwig Institute for Cancer Research Ltd., New York Branch of Human Cancer Immunology at Memorial Sloan-Kettering, New York, NY, USA.; Current address: Orygen Biotecnologia S.A., São Paulo, Brazil., Su T; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA., Yan X; Division of Colon and Rectal Surgery, Department of Surgery, Lenox Hill Hospital, Northwell Health, New York, NY 10028, USA., Ahmed A; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA., Herath SAC; University of Vermont Medical Center, Internal Medicine Hospitalist Service, Burlington, VT 05401, USA., Cekic V; Division of Colon and Rectal Surgery, Department of Surgery, Lenox Hill Hospital, Northwell Health, New York, NY 10028, USA., Njoh L; Department of Mathematics, City University of New York at Lehman College, Bronx, NY 10468, USA., Kirchoff DD; Roper St. Francis Physician Partners Surgical Oncology, Charleston, SC 29403, USA., Whelan RL; Division of Colon and Rectal Surgery, Department of Surgery, Lenox Hill Hospital, Northwell Health, New York, NY 10028, USA.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA.

Publikováno v: Oncotarget [Oncotarget] 2021 Mar 02; Vol. 12 (5), pp. 412-421. Date of Electronic Publication: 2021 Mar 02 (Print Publication: 2021).