Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Heqiao Li"'
Autor:
Huizi Li, Wenhui Fan, Jie Min, Xiaoyuan Bai, Wenxian Yang, Heqiao Li, Yuna Zhao, Runshan Lin, Xiaojuan Jia, Wenjun Liu, Lei Sun
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108515- (2023)
Summary: Influenza B circulates annually and causes substantial disease burden in humans. However, little is known about the infection mechanisms of influenza B virus (IBV). Here, we find that the host factor cyclophilin A (CypA) facilitates IBV repl
Externí odkaz:
https://doaj.org/article/639de804e3114b26a90a1346a6922872
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107535- (2023)
Summary: Cytokine storms caused by viruses are associated with elevated cytokine levels and uncontrolled inflammatory responses that can lead to acute respiratory distress syndrome. Current antiviral therapies are not sufficient to prevent or treat t
Externí odkaz:
https://doaj.org/article/6afc0cb4226b4b2194e57f35dd7a1789
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cyclosporine A (CsA) is an immunosuppressive drug that suppresses T cell responses and is broadly used in transplantation. Its immunosuppressive action is closely linked to its binding of cyclophilin A (CypA), which widely distributed in different ce
Externí odkaz:
https://doaj.org/article/fafc37d1dca0450b88afcce871b41ceb
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Epithelial–mesenchymal transition (EMT) is an important mechanism of lung tissue repair after injury, but excessive EMT may lead to pulmonary fibrosis, respiratory failure, and even death. The EMT triggered by influenza A virus (IAV) and influenza
Externí odkaz:
https://doaj.org/article/d69e281ce87047f0a0de890393e7c8fb
Autor:
Xiaoyuan Bai, Wenxian Yang, Xiaohan Luan, Huizi Li, Heqiao Li, Deyu Tian, Wenhui Fan, Jing Li, Beinan Wang, Wenjun Liu, Lei Sun
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109159- (2021)
Summary: During influenza A epidemics, bacterial coinfection is a major cause of increased morbidity and mortality. However, the roles of host factors in regulating influenza A virus (IAV)-triggered bacterial coinfection remain elusive. Cyclophilin A
Externí odkaz:
https://doaj.org/article/5487497c629940b894484b2c32a4ee3e
Autor:
Xingzhao Ji, Xiujuan Zhang, Lina Sun, Xuexin Hou, Han Song, Lichao Han, Shuai Xu, Heqiao Li, Xiaotong Qiu, Minghui Li, Xuebing Wang, Ningwei Zheng, Zhenjun Li
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Heparin-binding hemagglutinin (HBHA) from mycobacteria is involved in the dissemination of infection and the activation of the host immune response. However, the interaction of Nocardia cyriacigeorgica HBHA with the host cells remains unknown. In the
Externí odkaz:
https://doaj.org/article/19188673b18b4ecc885079d12b8719a5
Autor:
Wenxian Yang, Xiaoyuan Bai, Xiaohan Luan, Jie Min, Xiaodong Tian, Heqiao Li, Huizi Li, Wenqiang Sun, Wei Liu, Wenhui Fan, Wenjun Liu, Lei Sun
Publikováno v:
Cell reports. 38(11)
The inflammatory response is tightly regulated, but its regulatory principles are still incompletely understood. Cyclophilin A (CypA) has long been considered as a pro-inflammatory factor. Here, we discover how CypA precisely regulates interleukin-1
Autor:
Wenjun Liu, He Zhang, Heqiao Li, Xiaoyuan Bai, Wenxian Yang, Xiaohan Luan, Lei Sun, Wenhui Fan, H. J. Li
Publikováno v:
The FASEB Journal. 35
Cyclophilin A (CypA), a member of the cyclophilin family, plays a vital role in microorganismal infections, inflammatory diseases, and cancers. Interleukin-6 (IL-6) is a pleiotropic cytokine, exerting variety of effects on inflammation, immune respon
Autor:
Xiaotong Qiu, Xingzhao Ji, Lichao Han, Ningwei Zheng, Heqiao Li, Shuai Xu, Xiujuan Zhang, Lina Sun, Xuexin Hou, Zhenjun Li, Xuebing Wang, Han Song
Publikováno v:
Infection and Immunity. 88
The mechanism underlying the pathogenesis of Nocardia is not fully known. The Nfa34810 protein of Nocardia farcinica has been predicted to be a virulence factor. However, relatively little is known regarding the interaction of Nfa34810 with host cell
Autor:
Xiaotong Qiu, Lichao Han, Shuai Xu, Xuebing Wang, Xiujuan Zhang, Xuexin Hou, Han Song, Zhenjun Li, Minghui Li, Lina Sun, Heqiao Li, Ningwei Zheng, Xingzhao Ji
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Heparin-binding hemagglutinin (HBHA) from mycobacteria is involved in the dissemination of infection and the activation of the host immune response. However, the interaction of Nocardia cyriacigeorgica HBHA with the host cells remains unknown. In the