Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Hepworth, MR"'
Autor:
Mayer, JU, Hilligan, KL, Chandler, JS, Eccles, DA, Old, SI, Domingues, RG, Yang, J, Webb, GR, Munoz-Erazo, L, Hyde, EJ, Wakelin, KA, Tang, S-C, Chappell, SC, von Daake, S, Brombacher, F, Mackay, CR, Sher, A, Tussiwand, R, Connor, LM, Gallego-Ortega, D, Jankovic, D, Le Gros, G, Hepworth, MR, Lamiable, O, Ronchese, F
The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral environments remain mostly undefined. We show that differentiation of CD11blo migratory DC2s-a DC2 population unique to the dermis-required IL-13 signaling depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::a14b4bc3684d6ce9b52b24f4aebbeeb3
https://hdl.handle.net/10453/156211
https://hdl.handle.net/10453/156211
Autor:
Melo-Gonzalez, F, Kammoun, H, Evren, E, Dutton, EE, Papadopoulou, M, Bradford, BM, Tanes, C, Fardus-Reid, F, Swann, JR, Bittinger, K, Mabbott, NA, Vallance, BA, Willinger, T, Withers, DR, Hepworth, MR
Publikováno v:
Melo Gonzalez, F, Kammoun, H, Evren, E, Dutton, E E, Papadopoulou, M, Bradford, B M, Tanes, C, Fardus-Reid, F, Swann, J, Bittinger, K, Mabbott, N A, Vallance, B A, Willinger, T, Withers, D & Hepworth, M 2019, ' Antigen presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria ', Journal of Experimental Medicine, vol. 216, no. 4, pp. 728-742 . https://doi.org/10.1084/jem.20180871
Intestinal immune homeostasis is dependent upon tightly regulated and dynamic host interactions with the commensal microbiota. Immunoglobulin A (IgA) produced by mucosal B cells dictates the composition of commensal bacteria residing within the intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f7f748707cf3a698fad145b95d2de9e0
https://eprints.soton.ac.uk/440861/
https://eprints.soton.ac.uk/440861/
Publikováno v:
Science
Inflammatory CD4+ T cell responses to self or commensal bacteria underlie the pathogenesis of autoimmunity and inflammatory bowel disease (IBD) respectively. Although selection of self specific T cells in the thymus limits responses to mammalian tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=snsf_p3_pubs::bf33fd5eda40f00f344f992f07bcddae
Akademický článek
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Akademický článek
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Autor:
Roberts LB; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9PL, United Kingdom. Electronic address: luke.roberts@manchester.ac.uk., Neves JF; Centre for Host-Microbiome Interactions, King's College London, Great Maze Pond, London SE1 9RT, United Kingdom., Lee DCH; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9PL, United Kingdom., Valpione S; The Christie NHS Foundation Trust, 550 Wilmslow Road, M20 4BX Manchester, United Kingdom; Division of Cancer Sciences, The University of Manchester, Oxford Road, M13 9PL Manchester, United Kingdom; Cancer Research UK National Biomarker Centre, Wilmslow Road, M20 4BX Manchester, United Kingdom., Tachó-Piñot R; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9PL, United Kingdom., Howard JK; School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, Great Maze Pond, London SE1 9RT, United Kingdom., Hepworth MR; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9PL, United Kingdom., Lord GM; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9PL, United Kingdom; Centre for Gene Therapy and Regenerative Medicine, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, United Kingdom. Electronic address: graham.lord@kcl.ac.uk.
Publikováno v:
Mucosal immunology [Mucosal Immunol] 2024 Sep 07. Date of Electronic Publication: 2024 Sep 07.
Autor:
Bessell E; William Harvey Research Institute (WHRI), Barts & The London School of Medicine & Dentistry, Queen Mary University of London (QMUL), London, UK; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland; Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland., Finlay RE; Division of Immunology, Immunity to Infection and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, UK., James LK; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK., Ludewig B; Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland., Harris NL; Department of Immunology and Pathology, Central Clinical School, Monash University, The Alfred Centre, Melbourne, VIC, Australia., Krebs P; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland., Hepworth MR; Division of Immunology, Immunity to Infection and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, UK., Dubey LK; William Harvey Research Institute (WHRI), Barts & The London School of Medicine & Dentistry, Queen Mary University of London (QMUL), London, UK; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland. Electronic address: lalit.dubey@qmul.ac.uk.
Publikováno v:
Cell reports [Cell Rep] 2024 Aug 27; Vol. 43 (8), pp. 114620. Date of Electronic Publication: 2024 Aug 13.
Autor:
McClure FA; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Wemyss K; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Cox JR; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Bridgeman HM; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Prise IE; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., King JI; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Jaigirdar S; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Whelan A; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Jones GW; Cellular and Molecular Medicine, University of Bristol , Bristol, UK., Grainger JR; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Hepworth MR; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK., Konkel JE; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK.
Publikováno v:
The Journal of experimental medicine [J Exp Med] 2024 Aug 05; Vol. 221 (8). Date of Electronic Publication: 2024 May 31.
Autor:
Read E; Centre for Host Microbiome Interactions, King's College London, London, UK; Wellcome Trust Advanced Therapies and Regenerative Medicine PhD Programme, London, UK., Peña-Cearra A; Centre for Host Microbiome Interactions, King's College London, London, UK; Department of Immunology, Microbiology and Parasitology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Bilbao, Spain., Coman D; Centre for Host Microbiome Interactions, King's College London, London, UK., Jowett GM; Centre for Host Microbiome Interactions, King's College London, London, UK; Wellcome Trust Advanced Therapies and Regenerative Medicine PhD Programme, London, UK; Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Chung MWH; Wellcome Trust Advanced Therapies and Regenerative Medicine PhD Programme, London, UK; Centre for Gene Therapy & Regenerative Medicine, Kinǵs College, London, UK; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College, London, UK., Coales I; Centre for Host Microbiome Interactions, King's College London, London, UK., Syntaka S; Wellcome Trust Advanced Therapies and Regenerative Medicine PhD Programme, London, UK; Centre for Gene Therapy & Regenerative Medicine, Kinǵs College, London, UK., Finlay RE; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, the University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Tachó-Piñot R; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, the University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., van Der Post S; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden., Naizi U; Guy's and St Thomas' National Health Service Foundation Trust and King's College London National Institute for Health Research and Social Care, Biomedical Research Centre Translational Bioinformatics Platform, Guy's Hospital, London, UK., Roberts LB; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College, London, UK; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, the University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Hepworth MR; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, the University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Curtis MA; Centre for Host Microbiome Interactions, King's College London, London, UK., Neves JF; Centre for Host Microbiome Interactions, King's College London, London, UK. Electronic address: joana.pereira_das_neves@kcl.ac.uk.
Publikováno v:
Mucosal immunology [Mucosal Immunol] 2024 Feb; Vol. 17 (1), pp. 1-12. Date of Electronic Publication: 2023 Nov 10.
Autor:
Dean I; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Lee CYC; Department of Medicine, Molecular Immunity Unit, Medical Research Council Laboratory of Molecular Biology, University of Cambridge, Cambridge, UK.; Cellular Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Tuong ZK; Department of Medicine, Molecular Immunity Unit, Medical Research Council Laboratory of Molecular Biology, University of Cambridge, Cambridge, UK.; Cellular Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Li Z; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Tibbitt CA; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden., Willis C; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Gaspal F; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Kennedy BC; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Matei-Rascu V; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Fiancette R; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Nordenvall C; Department of Molecular Medicine and Surgery, Karolinska Institutet and Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden., Lindforss U; Department of Molecular Medicine and Surgery, Karolinska Institutet and Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden., Baker SM; Division of Informatics, Imaging & Data Science, Faculty of Biology, Medicine and Health, the University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Stockmann C; Institute of Anatomy, University of Zurich, Zurich, Austria., Sexl V; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria., Hammond SA; Early Oncology R&D, AstraZeneca, MD, USA., Dovedi SJ; Early Oncology R&D, AstraZeneca, UK., Mjösberg J; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Clinical Lung and Allergy Research, Medical unit for Lung and Allergy Diseases, Karolinska University Hospital, Stockholm, Sweden., Hepworth MR; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, the University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Carlesso G; Early Oncology R&D, AstraZeneca, MD, USA., Clatworthy MR; Department of Medicine, Molecular Immunity Unit, Medical Research Council Laboratory of Molecular Biology, University of Cambridge, Cambridge, UK. mrc38@medschl.cam.ac.uk.; Cellular Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. mrc38@medschl.cam.ac.uk., Withers DR; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. d.withers@bham.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2024 Jan 24; Vol. 15 (1), pp. 683. Date of Electronic Publication: 2024 Jan 24.