Zobrazeno 1 - 10
of 317
pro vyhledávání: '"Hepoxilin"'
Autor:
Katir K. Patel, Wilmore C. Webley
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Hepoxilins are biologically active metabolites of arachidonic acid that are formed through the 12-lipoxygenase pathway. Hepoxilin A3 is now known to be an important regulator of mucosal inflammation in response to infection by bacterial p
Externí odkaz:
https://doaj.org/article/e49589082ee04b5b8ca4694d12704631
Autor:
Andrew Zukauskas, Randall J. Mrsny, Paula Cortés Barrantes, Jerrold R. Turner, John M. Leong, Beth A. McCormick
Publikováno v:
mSphere, Vol 3, Iss 4 (2018)
ABSTRACT Streptococcus pneumoniae remains a source of morbidity and mortality in both developed and underdeveloped nations of the world. Disease can manifest as pneumonia, bacteremia, and meningitis, depending on the localization of infection. Intere
Externí odkaz:
https://doaj.org/article/4b7d319a3177468ebc2a90249196cf2b
Akademický článek
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Autor:
Elsa N. Bou Ghanem, Rudra Bhowmick, Rodney K. Tweten, Kristin R. Wade, Beth A. McCormick, Jeffrey N. Weiser, John M. Leong, Mikhail Shchepetov, Walter Adams
Publikováno v:
The Journal of Immunology. 204:101-111
Streptococcus pneumoniae is a major cause of pneumonia, wherein infection of respiratory mucosa drives a robust influx of neutrophils. We have previously shown that S. pneumoniae infection of the respiratory epithelium induces the production of the 1
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 2, Pp 292-299 (2012)
Conversion of fatty acid hydroperoxides to epoxyalcohols is a well known secondary reaction of lipoxygenases, described for S-specific lipoxygenases forming epoxyalcohols with a trans-epoxide configuration. Here we report on R-specific lipoxygenase s
Externí odkaz:
https://doaj.org/article/35f83385e9e74d5281d9b786d876f67e
Akademický článek
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Publikováno v:
Current molecular pharmacology. 15(5)
Abstract: Epoxide hydrolase (EH) is a crucial enzyme responsible for catabolism, detoxification, and regulation of signaling molecules in various organisms including human beings. In mammals, EHs are classified according to their DNA sequence, sub-ce
Autor:
Rose L. Szabady, Beth A McCormick
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
The human intestine is a large and delicately balanced organ, responsible for efficiently absorbing nutrients and selectively eliminating disease-causing pathogens. The gut architecture consists of a single layer of epithelial cells that forms a barr
Externí odkaz:
https://doaj.org/article/864ace8d59234f1bb03f0f961643e9f7
Autor:
Roger Gregory Biringer
Publikováno v:
Molecular biology reports. 47(9)
Eicosanoids are short-lived derivatives of polyunsaturated fatty acids that serve as autocrine and paracrine signaling molecules. They are involved numerous biological processes of both the well state and disease states. A thorough understanding of t
Autor:
Fumie Kinoshita, Masashi Akiyama, Hirotaka Tanaka, Yumiko Kobayashi, Masahiro Nakatochi, Setsuko Fujita, Kazumitsu Sugiura, Takuya Takeichi
Publikováno v:
Journal of Cutaneous Immunology and Allergy. 2:15-24