Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

Autor: Martial Marbouty, Stefano Cairo, Christine Neuveut, Romain Koszul, Agnès Thierry, Gianna Aurora Palumbo, Marc Lavigne, Shogofa Mortaza, Axel Cournac, Pierrick Moreau

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.4268. ⟨10.1038/s41467-018-06739-4⟩
Nature Communications, 2018, 9 (1), pp.4268. ⟨10.1038/s41467-018-06739-4⟩

Whether non-integrated viral DNAs distribute randomly or target specific positions within the higher-order architecture of mammalian genomes remains largely unknown. Here we use Hi-C and viral DNA capture (CHi-C) in primary human hepatocytes infected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25a01ae3ff182b3c56e2c98435fe5a3
http://link.springer.com/article/10.1038/s41467-018-06739-4

Vectorial Release of Hepatitis E Virus in Polarized Human Hepatocytes

Autor: Jacques Izopet, Olivier Marion, Sophie Allart, Sébastien Lhomme, Sabine Chapuy-Regaud, Justine Bertrand-Michel, Nicolas Capelli, Martine Dubois, Florence Abravanel

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2019, 93 (4), ⟨10.1128/JVI.01207-18⟩

International audience; Hepatitis E virus (HEV) is a common cause of acute viral hepatitis worldwide. Most HEV infections are asymptomatic, but immunocompromised patients infected with HEV genotype 3 (HEV3), HEV4, or HEV7 may develop chronic infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc46e65d9d7539bf8694a2a8b742c79
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03608725

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry

Autor: Sandrine Belouzard, Jens Bukh, Lucie Fénéant, Priscille Brodin, Yves Rouillé, Jean Dubuisson, Laura Riva, Thomas F. Baumert, Alexandre Vandeputte, François Helle, Jannick Prentoe, Laurent L'homme, Laurence Cocquerel, Charles-Henry Gattolliat, Ok-Ryul Song, Tarik Asselah

Publikováno v: Journal of Virology
Journal of Virology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩
Journal of Virology, American Society for Microbiology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩

Hepatitis C virus (HCV) infection causes 500,000 deaths annually, in association with end-stage liver diseases. Investigations of the HCV life cycle have widened the knowledge of virology, and here we discovered that two piperazinylbenzenesulfonamide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eede9d22a44a24224a0d9eb270333e63
https://pubmed.ncbi.nlm.nih.gov/29491159

FIG4 is a Hepatitis C Virus particle-bound protein implicated in virion morphogenesis and infectivity with cholesteryl ester modulation potential

Autor: Jessica Cottarel, Sharon J. Pitteri, Majlinda Kullolli, Si-Nafa Si-Ahmed, Romain Parent, Sophie Clément, Hesso Farhan, Fabien Zoulim, Valentina Millarte, Marie-Laure Plissonnier

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 2016, 97 (1), pp.69-81. ⟨10.1099/jgv.0.000331⟩
Journal of General Virology, Vol. 97, No 1 (2016) pp. 69-81

International audience; There is growing evidence that virus particles also contain host cell proteins, which provide viruses with certain properties required for entry and release. A proteomic analysis performed on double-gradient-purified hepatitis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7191ee3868ea4827385d71da92d8b0
https://zenodo.org/record/35036

Identification of Novel Compounds Inhibiting Chikungunya Virus-Induced Cell Death by High Throughput Screening of a Kinase Inhibitor Library

Autor: Camila T. da Silva, Joo Hwan No, Michael Adsetts Edberg Hansen, Olivier Schwartz, Deu John M. Cruz, Rafaela Milan Bonotto, Lucio H. Freitas-Junior, Juliana B. Taniguchi, Rafael G. B. Gomes, Benoit Lombardot

Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2012, 7 (10), pp.e2471. ⟨10.1371/journal.pntd.0002471⟩
PLoS Neglected Tropical Diseases, 2012, 7 (10), pp.e2471. ⟨10.1371/journal.pntd.0002471⟩
PLoS Neglected Tropical Diseases, Vol 7, Iss 10, p e2471 (2013)

Chikungunya virus (CHIKV) is a mosquito-borne arthrogenic alphavirus that causes acute febrile illness in humans accompanied by joint pains and in many cases, persistent arthralgia lasting weeks to years. The re-emergence of CHIKV has resulted in num

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ee31113a39ce2c4f1e7d26bebb9bdc