Zobrazeno 1 - 10
of 1 426
pro vyhledávání: '"Hepatocyte-like cells"'
Autor:
Hui Liu, Xiaojuan Bi, Ning Yang, Xue Zhang, Bingbing Fang, Nuerbaiti Kusuman, Wenmei Ma, Jing Li, Jin Chu, Li Sun, Liang Li, Guodong Lü, Renyong Lin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Accumulating evidence has shown that adipose-derived stem cells (ADSCs) have the potential to differentiate into hepatic lineages, which are ideal engraftments for tissue-engineered repair. In this study, we investigated the potential of tra
Externí odkaz:
https://doaj.org/article/27517f06079e4ba293f949041513bf57
Autor:
Pedro Vicente, Joana I. Almeida, Inês E. Crespo, Nikolaus Virgolini, Inês A. Isidro, Maria Eréndira Calleja-Cervantes, Juan R. Rodriguez-Madoz, Felipe Prosper, Paula M. Alves, Margarida Serra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Hepatocytes-like cells (HLC) derived from human induced pluripotent stem cells show great promise for cell-based liver therapies and disease modelling. However, their application is currently hindered by the low production yields of existing
Externí odkaz:
https://doaj.org/article/70c758a07bc245059b4c1832ecd92381
Autor:
Zhi Zhong, Xiu-Liang Cui, Kun-Jiang Tan, Xiang-Yu Wu, Xiang-Jie Zhu, Jiu-Yu Zhang, Wei-Jia Zhang, Hong-Yang Wang, Pei-Lin Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Liver fibrosis is a serious global health issue for which effective treatment remains elusive. Chemical-induced hepatocyte-like cells (ciHeps) have emerged as an appealing source for cell transplantation therapy, although they present severa
Externí odkaz:
https://doaj.org/article/bd54c445ed644af4aa3ade57346234e5
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103534- (2024)
The lack of equitable representation of African diversity in scientific resources, such as genome-wide association studies and human induced pluripotent stem cell (hiPSC) repositories, has perpetuated inequalities in the advancement of health researc
Externí odkaz:
https://doaj.org/article/16a617cb72494d95a2b0af4b34da9851
Autor:
Roselle Gélinas, Chloé Lévesque, Julie Thompson Legault, Marie-Eve Rivard, Louis Villeneuve, Catherine Laprise, John D. Rioux
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Leigh syndrome French Canadian type (LSFC) is a recessive neurodegenerative disease characterized by tissue-specific deficiency in cytochrome c oxidase (COX), the fourth complex in the oxidative phosphorylation system. LSFC is caused by mutations in
Externí odkaz:
https://doaj.org/article/8e98851c8f244ed8b792433bcf54a932
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The generation of iPSC-derived hepatocyte-like cells (HLCs) is a powerful tool for studying liver diseases, their therapy as well as drug development. iPSC-derived disease models benefit from their diverse origin of patients, enabling the study of di
Externí odkaz:
https://doaj.org/article/37f1b8af35204c5394ffd74cbb512d35
Autor:
Yuanyuan Jin, Jiabin Zhang, Yanteng Xu, Ke Yi, Fenfang Li, Huicong Zhou, Haixia Wang, Hon Fai Chan, Yeh-Hsing Lao, Shixian Lv, Yu Tao, Mingqiang Li
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 112-131 (2023)
Reactive oxygen species (ROS)-associated oxidative stress, inflammation storm, and massive hepatocyte necrosis are the typical manifestations of acute liver failure (ALF), therefore specific therapeutic interventions are essential for the devastating
Externí odkaz:
https://doaj.org/article/9d76953081d14a12a517610f55416961
Autor:
Yong-Hong Wang, En-Qiang Chen
Publikováno v:
Gut and Liver, Vol 17, Iss 5, Pp 674-683 (2023)
Acute liver failure (ALF) is a severe liver disease syndrome with rapid deterioration and high mortality. Liver transplantation is the most effective treatment, but the lack of donor livers and the high cost of transplantation limit its broad applica
Externí odkaz:
https://doaj.org/article/3d81c73e12e245f886dcabfff7105654
Autor:
Guillem Garcia-Llorens, Teresa Martínez-Sena, Eugenia Pareja, Laia Tolosa, José V. Castell, Roque Bort
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Background High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells. However, these cells often display limited hepatic phenotype and features of neoplastic tran
Externí odkaz:
https://doaj.org/article/62a962e9da144657bf30508219281295
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.