Phenotypic differences and similarities of monozygotic twins with maturity‐onset diabetes of the young type 5

Autor: Yasuko Ohara, Yuko Okada, Tomoko Yamada, Kenji Sugawara, Masayuki Kanatani, Hidenori Fukuoka, Yushi Hirota, Takaki Maeda, Naoya Morisada, Kazumoto Iijima, Wataru Ogawa

Publikováno v: Journal of Diabetes Investigation, Vol 10, Iss 4, Pp 1112-1115 (2019)

Abstract Here, we report phenotypic differences and similarities of monozygotic twins with maturity‐onset diabetes of the young type 5 harboring a partial deletion of chromosome 17q12. The proband and her twin sister manifested complete aplasia and

Externí odkaz: https://doaj.org/article/e4daed46eef140e3b48224abcee67504

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Inhibition of hepatocyte nuclear factor 1β contributes to cisplatin nephrotoxicity via regulation of nf‐κb pathway

Autor: Yuanfang Ma, Peiyao Li, Shulian Li, Yan Zhang, Jielu Hao, Zijun Du, Mengna Ruan, Jinghua Hu, Qiang Lou

Publikováno v: Journal of Cellular and Molecular Medicine

Cisplatin nephrotoxicity has been considered as serious side effect caused by cisplatin‐based chemotherapy. Recent evidence indicates that renal tubular cell apoptosis and inflammation contribute to the progression of cisplatin‐induced acute kidn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c682a432c64b56b8f378e678f1d080
https://doi.org/10.1111/jcmm.16316

Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6Summary

Autor: Maureen Gannon, Peter A. Kropp, Xiaodong Zhu

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 841-856 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims The Onecut 1 transcription factor (Oc1, a.k.a. HNF6) promotes differentiation of endocrine and duct cells of the pancreas; however, it has no known role in acinar cell differentiation. We sought to better understand the role of Oc1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8340f4db90d84f348eeb0763345455be
http://www.sciencedirect.com/science/article/pii/S2352345X19300207

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