Zobrazeno 1 - 10
of 1 839
pro vyhledávání: '"Hepatitis B virus PRE beta"'
Publikováno v:
The Liver
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e65456 (2013)
PLoS ONE, Vol 8, Iss 5, p e65456 (2013)
Occult hepatitis B virus (HBV) infection is defined as persistence of HBV DNA in liver tissues, with or without detectability of HBV DNA in the serum, in individuals with negative serum HBV surface antigen (HBsAg). Despite accumulating evidence sugge
Autor:
Monsef Benkirane, Aurélie Ducroux, Shirine Benhenda, Lise Rivière, Christine Neuveut, O. John Semmes
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009135 (2020)
PLoS Pathogens, Vol 10, Iss 9, p e1004343 (2014)
PLoS Pathogens
PLoS Pathogens, 2014, 10, ⟨10.1371/journal.ppat.1004343.s004⟩
PLoS Pathogens, Public Library of Science, 2014, 10, ⟨10.1371/journal.ppat.1004343.s004⟩
PLoS Pathogens, Vol 10, Iss 9, p e1004343 (2014)
PLoS Pathogens
PLoS Pathogens, 2014, 10, ⟨10.1371/journal.ppat.1004343.s004⟩
PLoS Pathogens, Public Library of Science, 2014, 10, ⟨10.1371/journal.ppat.1004343.s004⟩
International audience; Hepatitis B virus infection (HBV) is a major risk factor for the development of hepatocellular carcinoma. HBV replicates from a covalently closed circular DNA (cccDNA) that remains as an episome within the nucleus of infected
Autor:
Gotchev Dimitar B, Timothy M. Block, Tianlun Zhou, Xiaohe Wang, Jeffrey D. Branson, Rene Rijnbrand, Tim T. Chiu, Michael J. Sofia, Chris B. Moore, Fang Guo, Hongyan Liang, Troy Harasym, Bruce D. Dorsey, Min Gao, Siddhartha Rawat, Amy C.H. Lee, Liren Sun, Bailey Lauren Danielle, Fei Liu, Andy Cuconatti, Holly M. Micolochick Steuer, Andrew S. Kondratowicz
Publikováno v:
Antiviral Research. 149:191-201
In pursuit of novel therapeutics targeting the hepatitis B virus (HBV) infection, we evaluated a dihydroquinolizinone compound (DHQ-1) that in the nanomolar range reduced the production of virion and surface protein (HBsAg) in tissue culture. This co
Autor:
Yao Huang, Ni Tang, Zeng Tu, Jie Hu, Yanmeng Chen, Xing Zhou, Yuan Hu, Ailong Huang, Jieli Hu, Xue-Fei Cai, John E. Tavis
Publikováno v:
Antiviral Research. 149:16-25
Hepatitis B virus is a partially double-stranded DNA virus that replicates by reverse transcription, which occurs within viral core particles in the cytoplasm. The cytidine deaminase APOBEC3B is a cellular restriction factor for HBV. Recently, it was
Autor:
Jing Zhang, Keisuke Harada, Saneyuki Ujino, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Masaya Sugiyama, Michinori Kohara
Publikováno v:
Cancer Science
Chronic infection with Hepatitis B virus (HBV) increases the risk of developing fibrosis, cirrhosis, or hepatocellular carcinoma. Current therapies are limited to type-I interferons and/or nucleos(t)ide analogues; however, these are only partially ef
Publikováno v:
Frontiers of Medicine. 11:502-508
Although the efficacy of nucleos(t)ide analogue (NA) has been confirmed for treatment of chronic hepatitis B, long-term therapy has been recommended due to the high frequency of off-therapy viral DNA rebound and disease relapse. In this review, the R
Publikováno v:
World Chinese Journal of Digestology. 25:2782-2790
Publikováno v:
Virus Research
Highlights • The impact of BCP mutations on HBV-X biologic activity was analyzed. • Genotype F wild type and mutant HBV-X induce apoptosis of human hepatocytes. • HBV-X variants modulate the expression of Bcl-2 family proteins. • Subgenotypes
Autor:
Masahiko Ito, Suofeng Sun, Kenji Nakashima, Takeshi Chida, Hirotaka Takahashi, Tatsuya Sawasaki, Takaji Wakita, Koichi Watashi, Tetsuro Suzuki, Yuan Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Here we identified PUF60, a splicing factor and a U2 small nuclear ribonucleoprotein auxiliary factor, as a versatile regulator of transcriptional and post-transcriptional steps in expression of hepatitis B virus (HBV) 3.5 kb, precore plus pregenomic