Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Hepatic microsome"'
Publikováno v:
Journal of Medicinal Food. 21:1173-1187
In the present study, Bojungikgi-tang (BJIKT: Buzhongyiqi-tang, Hochuekki-to) and Palmijihwang-hwan (PMJHH: Baweidìhuang-wan, Hachimijio-gan), traditional herbal formulas, investigated anti-inflammatory efficacies in murine macrophage cell line and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaa8d46863d8feea09daecc122664b1
https://doi.org/10.1089/jmf.2017.4123
https://doi.org/10.1089/jmf.2017.4123
Publikováno v:
Drug Metabolism and Pharmacokinetics. 33:31-39
Predicting human drug metabolism and pharmacokinetics (PK) is key to drug discovery. In particular, it is important to predict human PK, metabolite profiles and drug-drug interactions (DDIs). Various methods have been used for such predictions, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b65810d93b15559ac0ef4f454d50bbe
https://doi.org/10.1016/j.dmpk.2017.11.001
https://doi.org/10.1016/j.dmpk.2017.11.001
Akademický článek
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Autor:
Frédéric Aknouche, Christophe Maruejouls, Pascal Kintz, Jean-Michel Gaulier, Audrey Coulon, Camille Richeval, Alice Ameline, Anne-Julie Schapira
The authors aim to report a case of surreptitious administration of a synthetic cannabinoid (SC) and the subsequent toxicological investigations to be able to document accurately the case for submission at a hearing. A dealer gave surreptitiously a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58928d67755c076b6aeff3e570cd2cb
http://hdl.handle.net/20.500.12210/59644
http://hdl.handle.net/20.500.12210/59644
Autor:
Katsuhito Nagai, Hiroki Konishi, Takeshi Nabe, Kohei Yamamoto, Shuhei Fukuno, Takehiro Tanimura
Publikováno v:
Biopharmaceuticsdrug disposition. 40(7)
The study examined the effect of doxorubicin (DOX) on the hepatic expression of CYP2C and its activity for metabolizing tolbutamide (TB), a specific CYP2C substrate, in rats and whether the pharmacokinetics of tolbutamide were altered by doxorubicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f91c5795565c44ee0d1bcde3c7d7077
https://pubmed.ncbi.nlm.nih.gov/31215040
https://pubmed.ncbi.nlm.nih.gov/31215040
Publikováno v:
Open Journal of Fisheries Research. :88-96
目的：研究不同浓度烟酸诺氟沙星对乌鳢肝微粒体细胞色素P450酶系的影响，旨在为水产养殖合理用药提供安全指导。方法：健康乌鳢60尾，体重200 ± 20.0 g，随机分为空白对照组、低剂量(5 mg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c29647b8b9a5dbf42693d5f802a0a50c
https://doi.org/10.12677/ojfr.2016.34014
https://doi.org/10.12677/ojfr.2016.34014
Akademický článek
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Publikováno v:
Environmental Science and Pollution Research. 28:336-336
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708a7efc82ac9542e4323eb6a6c7e9e3
https://doi.org/10.1007/s11356-020-11646-7
https://doi.org/10.1007/s11356-020-11646-7
Autor:
Naizhi Wang, Wenjuan Cui, Xincheng Wang, Zhaolong Zhang, Xiaoguang Fan, Zhikun Zhang, Guanghu Yang
Publikováno v:
Natural Product Communications. 15:1934578X2091501
Kaji-ichigoside F1, a pentacyclic triterpenoid saponin, exhibits various beneficial pharmacological effects. In this study, a simple, rapid, and specific high-performance liquid chromatography-tandem mass spectrometry method for rapid quantification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0868a0478a13ae87f8f66543db3e4216
https://doi.org/10.1177/1934578x20915018
https://doi.org/10.1177/1934578x20915018
Publikováno v:
Environmental toxicology and pharmacology. 62
Naturally- and anthropogenically-produced cresols could pose serious risks to fish health. In this study, three piscine CYP isoforms were investigated for their abilities to interact with p-cresol. Therefore, the activity of 7-ethoxyresorufin-O-deeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10e5ad3b2007e7b5bb7298410089a58
https://pubmed.ncbi.nlm.nih.gov/30077163
https://pubmed.ncbi.nlm.nih.gov/30077163