Výsledky vyhledávání - "Hepatic lipase deficiency"

Evidence of a polygenic origin of extreme high-density lipoprotein cholesterol levels

Autor: M. Mahdi Motazacker, G. Kees Hovingh, Jorge Peter, Carol C. Shoulders, Jan Albert Kuivenhoven, Marco Treskes

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology, 33(7), 1521-1528. Lippincott Williams and Wilkins
Arteriosclerosis thrombosis and vascular biology, 33(7), 1521-1528. LIPPINCOTT WILLIAMS & WILKINS

Objective— There are several known monogenic causes of high and low high-density lipoprotein cholesterol (HDL-C) levels, but traditional sequencing studies have had limited success in identifying mutations in the majority of individuals with extrem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad99511bc90d2e92158d7630e119313
https://hdl.handle.net/11370/9f9b3387-91cd-440d-9bb7-f996408cb4b6

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The promise of cholesteryl ester transfer protein (CETP) inhibition in the treatment of cardiovascular disease

Publikováno v: Current Pharmaceutical Design. 19(17):3143-3149

There is a strong need to reduce the risk of cardiovascular disease (CVD) beyond the use of statins that lower low-density lipoprotein cholesterol (LDL-C). The inverse relationship of high-density lipoprotein cholesterol (HDL-C) with cardiovascular d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::b6f3914b2542611a72e8ec8cb72a2230
https://hdl.handle.net/11370/b5ef9855-192d-4658-b7aa-f28898566b1e

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Correspondence

Autor: Robert A. Hegele, J. A. Little, Philip W. Connelly

Publikováno v: Atherosclerosis. 143:219-222

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18067da688abd4e634c75f9e13a8c4bc
https://doi.org/10.1016/s0021-9150(98)00266-4

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Hepatic Lipase Deficiency Increases Plasma Cholesterol but Reduces Susceptibility to Atherosclerosis in Apolipoprotein E-deficient Mice

Autor: Nobuyo Maeda, Robert Jones, Graciela Castro, Catherine Dengremont, Hafid Mezdour

Publikováno v: Journal of Biological Chemistry. 272:13570-13575

The effect of hepatic lipase (HL) deficiency on the susceptibility to atherosclerosis was tested using mice with combined deficiencies in HL and apoE. Mice lacking both HL and apoE (hhee) have a plasma total cholesterol of 917 +/- 252 mg/dl (n = 24),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5da550efaead234f13ae3f7ac794e08
https://doi.org/10.1074/jbc.272.21.13570

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The promise of cholesteryl ester transfer protein (CETP) inhibition in the treatment of cardiovascular disease

Autor: Bochem, A. E., Kuivenhoven, J. A., Stroes, E. S. G.

Publikováno v: Current Pharmaceutical Design, 19(17), 3143-3149. BENTHAM SCIENCE PUBL LTD
Current pharmaceutical design, 19(17), 3143-3149. Bentham Science Publishers B.V.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fd9f95a304aa044ab7ccb6a71f94587a
https://research.rug.nl/en/publications/b5ef9855-192d-4658-b7aa-f28898566b1e

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Hepatic lipase deficiency in a Middle-Eastern-Arabic male

Autor: Abdullah M Al-Ali, Robert A. Hegele, Kishor M. Wasan, Kristina Sachs-Barrable, Jiri Frohlich, Nafila B. Al Riyami, John Walter Hill, Ahmad Al-Sarraf

Publikováno v: BMJ case reports. 2010

Summary Hepatic lipase (HL) defi ciency is a rare genetic disorder that has been associated with premature atherosclerosis despite high plasma highdensity lipoprotein (HDL) cholesterol concentrations in the affected individuals. The authors describe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb217a08f137e5137316767280531f05
https://pubmed.ncbi.nlm.nih.gov/22798447

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