Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Heparitin Sulfate/chemistry"'
Autor:
Jeremy E. Turnbull, Rebecca L. Miller, Kevin Pagel, Johanna Hofmann, Scott E. Guimond, Jian Liu, Yongmei Xu, Olga V. Zubkova, Márkó Grabarics, Weston B. Struwe, Peter C. Tyler, Christian Manz, Niclas G. Karlsson, Geert-Jan Boons, Pradeep Chopra, Ralf Schwörer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature communications
Miller, R L, Guimond, S E, Schwörer, R, Zubkova, O V, Tyler, P C, Xu, Y, Liu, J, Chopra, P, Boons, G-J, Grabarics, M, Manz, C, Hofmann, J, Karlsson, N G, Turnbull, J E, Struwe, W B & Pagel, K 2020, ' Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides ', Nature Communications, vol. 11, no. 1, 1481 . https://doi.org/10.1038/s41467-020-15284-y
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature communications
Miller, R L, Guimond, S E, Schwörer, R, Zubkova, O V, Tyler, P C, Xu, Y, Liu, J, Chopra, P, Boons, G-J, Grabarics, M, Manz, C, Hofmann, J, Karlsson, N G, Turnbull, J E, Struwe, W B & Pagel, K 2020, ' Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides ', Nature Communications, vol. 11, no. 1, 1481 . https://doi.org/10.1038/s41467-020-15284-y
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f920e85f68e62045bd2b08b912e7a3af
https://doaj.org/article/771c43443fb14659b5131577553e2f14
https://doaj.org/article/771c43443fb14659b5131577553e2f14
Autor:
Jones, Samuel
Publikováno v:
Jones, S 2020, ' Modified cyclodextrins as broad-spectrum antivirals ', Science Advances, vol. 6, no. 5, eaax9318 . https://doi.org/10.1126/sciadv.aax9318
Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal molecules described to date are cytotoxic. We recently devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::caf3af77e89e5dba46c254048d281d18
https://doi.org/10.1126/sciadv.aax9318
https://doi.org/10.1126/sciadv.aax9318
Autor:
Dhruv Thakar, Tracy M. Handel, Douglas P. Dyer, Elisa Migliorini, Ralf P. Richter, Catherina L. Salanga
Publikováno v:
Open Biology
Open Biology, Vol 7, Iss 1 (2017)
Open biology, vol 7, iss 1
Dyer, D P, Migliorini, E, Salanga, C L, Thakar, D, Handel, T M & Richter, R P 2017, ' Differential structural remodelling of heparan sulfate by chemokines : the role of chemokine oligomerization ', Open Biology, vol. 7, no. 1 . https://doi.org/10.1098/rsob.160286
Open Biology, Vol 7, Iss 1 (2017)
Open biology, vol 7, iss 1
Dyer, D P, Migliorini, E, Salanga, C L, Thakar, D, Handel, T M & Richter, R P 2017, ' Differential structural remodelling of heparan sulfate by chemokines : the role of chemokine oligomerization ', Open Biology, vol. 7, no. 1 . https://doi.org/10.1098/rsob.160286
Chemokines control the migration of cells in normal physiological processes and in the context of disease such as inflammation, autoimmunity and cancer. Two major interactions are involved: (i) binding of chemokines to chemokine receptors, which acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb06533150bb2c8593c88b893bb209a5
http://europepmc.org/articles/PMC5303277
http://europepmc.org/articles/PMC5303277
Autor:
Dagmar Sandbäck Pikas, Jacob van den Born, Jo H. M. Berden, Inger Eriksson, Brenda J.M. Pisa, Lena Kjellén
Publikováno v:
Glycobiology, 13(1), 1-10. Oxford University Press
Glycobiology, 13, 1-10
Glycobiology, 13, 1, pp. 1-10
Glycobiology, 13, 1-10
Glycobiology, 13, 1, pp. 1-10
Contains fulltext : 184929.pdf (Publisher’s version ) (Closed access) A new assay was developed to measure the N-deacetylase activity of the glucosaminyl N-deacetylase/N-sulfotransferases (NDSTs), which are key enzymes in sulfation of heparan sulfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c351dc237d73e9f5d0ded1ae474e0ccf
https://doi.org/10.1093/glycob/cwg011
https://doi.org/10.1093/glycob/cwg011
Publikováno v:
The Journal of Biological Chemistry. 270(52):31303-31309
Immunohistochemical application of antibodies against heparan sulfate proteoglycan core protein and heparitinase-digested heparan sulfate stubs showed the presence of heparan sulfate proteoglycan in all basement membranes of the rat kidney. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::e12b087abfd66c439a7932779f0a93d5
https://research.rug.nl/en/publications/45215167-f3ae-47cb-8482-05dd7c3a81f5
https://research.rug.nl/en/publications/45215167-f3ae-47cb-8482-05dd7c3a81f5
Autor:
Lena Kjellén, Marco Maccarana, Jhm Berden, Marion Kusche-Gullberg, Ulf Lindahl, Marinka A.H. Bakker, K. Gunnarsson, J. van den Born
Publikováno v:
Journal of Biological Chemistry, 270, 31303-31309
Journal of Biological Chemistry, 270, 52, pp. 31303-31309
The Journal of Biological Chemistry, 270(52), 31303-31309. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Biological Chemistry, 270, pp. 31303-31309
Journal of Biological Chemistry, 270, 52, pp. 31303-31309
The Journal of Biological Chemistry, 270(52), 31303-31309. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Biological Chemistry, 270, pp. 31303-31309
Immunohistochemical application of antibodies against heparan sulfate proteoglycan core protein and heparitinase-digested heparan sulfate stubs showed the presence of heparan sulfate proteoglycan in all basement membranes of the rat kidney. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d404e18aaaffc3cd0db16662d4638c36
https://hdl.handle.net/2066/216430
https://hdl.handle.net/2066/216430
Publikováno v:
Glycobiology, vol 26, iss 3
Dyer, D P, Salanga, C L, Volkman, B F, Kawamura, T & Handel, T M 2016, ' The dependence of chemokine-glycosaminoglycan interactions on chemokine oligomerization ', Glycobiology, vol. 26, no. 3, pp. 312-26 . https://doi.org/10.1093/glycob/cwv100
Dyer, D P, Salanga, C L, Volkman, B F, Kawamura, T & Handel, T M 2016, ' The dependence of chemokine-glycosaminoglycan interactions on chemokine oligomerization ', Glycobiology, vol. 26, no. 3, pp. 312-26 . https://doi.org/10.1093/glycob/cwv100
Both chemokine oligomerization and binding to glycosaminoglycans (GAGs) are required for their function in cell recruitment. Interactions with GAGs facilitate the formation of chemokine gradients, which provide directional cues for migrating cells. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13508109e13eb93097c2542991dd687c
https://doi.org/10.1093/glycob/cwv100
https://doi.org/10.1093/glycob/cwv100
Autor:
Marinka A.H. Bakker, Lena Kjellén, Steven Thomas, Brenda J.M. Pisa, Jo H. M. Berden, Gian C. Viberti, Johanna W.A.M. Celie, Jacob van den Born, Carin Straatman
Publikováno v:
The Journal of Biological Chemistry, 281(40), 29606-29613. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Biological Chemistry, 281, 29606-13
Journal of Biological Chemistry, 281, 40, pp. 29606-13
Journal of Biological Chemistry, 281, 29606-13
Journal of Biological Chemistry, 281, 40, pp. 29606-13
Contains fulltext : 49601.pdf (Publisher’s version ) (Open Access) Heparan sulfate (HS) proteoglycans are major anionic glycoconjugates of the glomerular basement membrane and are thought to contribute to the permeability properties of the glomerul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76d186848eeabcb1982dc6fd4b226b4
https://pubmed.ncbi.nlm.nih.gov/16885165
https://pubmed.ncbi.nlm.nih.gov/16885165
Autor:
Angelika M. Dräger, Suzanne Zuijderduijn, Sonja Zweegman, Peter C. Huijgens, Tanja Netelenbos, Jacob van den Born, Floortje L. Kessler
Publikováno v:
Journal of Leukocyte Biology, 72(2), 353-362. FEDERATION AMER SOC EXP BIOL
J. Leukoc. Biol., 72(2), 353-362
Netelenbos, T, Zuijderduijn, S, van den Born, J, Kessler, F L, Zweegman, S, Huijgens, P C & Drager, A M 2002, ' Proteoglycans guide SDF-1-induced migration of hematopoietic progenitor cells ', J. Leukoc. Biol., vol. 72, no. 2, pp. 353-362 . < http://www.jleukbio.org/cgi/content/abstract/72/2/353 >
J. Leukoc. Biol., 72(2), 353-362
Netelenbos, T, Zuijderduijn, S, van den Born, J, Kessler, F L, Zweegman, S, Huijgens, P C & Drager, A M 2002, ' Proteoglycans guide SDF-1-induced migration of hematopoietic progenitor cells ', J. Leukoc. Biol., vol. 72, no. 2, pp. 353-362 . < http://www.jleukbio.org/cgi/content/abstract/72/2/353 >
Stromal cell-derived factor-1 (SDF-1) is a chemoattractant involved in hematopoietic progenitor cell (HPC) trafficking to the bone marrow. We studied the role of bone marrow endothelial proteoglycans (PGs) in SDF-1-mediated migration of HPC using a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfa9b9bac85ba81d904dfcc05c45aaa
https://research.rug.nl/en/publications/5287fee9-d998-4b6e-929e-51a8aedef54d
https://research.rug.nl/en/publications/5287fee9-d998-4b6e-929e-51a8aedef54d
Autor:
C.H.A. van de Lest, J.-W.J. Lammers, C.L.A. van Herwaarden, A.H.M.S.M. van Kuppevelt, J. van den Born, P.N.R. Dekhuijzen, Leo M. A. Heunks, Elly M. M. Versteeg, J.H. Veerkamp, Jhm Berden
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 154(4), 952-958. AMER THORACIC SOC
Van De Lest, C H, Versteeg, E M, Veerkamp, J H, Berden, J H, Van Den Born, J, Heunks, L, Lammers, J W J, Van Herwaarden, C L, Dekhuijzen, P N R & Van Kuppevelt, T H 1996, ' Altered composition of urinary heparan sulfate in patients with COPD ', American Journal of Respiratory and Critical Care Medicine, vol. 154, no. 4 I, pp. 952-958 . https://doi.org/10.1164/ajrccm.154.4.8887591
American Journal of Respiratory and Critical Care Medicine, 154(4 I), 952-958. American Thoracic Society
American Journal of Respiratory and Critical Care Medicine, 154, pp. 952-958
American Journal of Respiratory and Critical Care Medicine, 154, 4, pp. 952-958
Scopus-Elsevier
American Journal of Respiratory and Critical Care Medicine, 154, 952-958
Van De Lest, C H, Versteeg, E M, Veerkamp, J H, Berden, J H, Van Den Born, J, Heunks, L, Lammers, J W J, Van Herwaarden, C L, Dekhuijzen, P N R & Van Kuppevelt, T H 1996, ' Altered composition of urinary heparan sulfate in patients with COPD ', American Journal of Respiratory and Critical Care Medicine, vol. 154, no. 4 I, pp. 952-958 . https://doi.org/10.1164/ajrccm.154.4.8887591
American Journal of Respiratory and Critical Care Medicine, 154(4 I), 952-958. American Thoracic Society
American Journal of Respiratory and Critical Care Medicine, 154, pp. 952-958
American Journal of Respiratory and Critical Care Medicine, 154, 4, pp. 952-958
Scopus-Elsevier
American Journal of Respiratory and Critical Care Medicine, 154, 952-958
In patients with emphysema the integrity of the extracellular matrix (connective tissue skeleton) is compromised. In this study we analyzed glycosaminoglycans, which are main constituents of this matrix, in urines from patients with chronic obstructi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f261a504bee40e5d43ee7d2c2aa646
https://research.rug.nl/en/publications/1b6f7e89-4f45-4bcf-8b94-fc8bf72bd87d
https://research.rug.nl/en/publications/1b6f7e89-4f45-4bcf-8b94-fc8bf72bd87d