Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation

Autor: Paul Johnson, A.J. McBride, Karl E. Kadler, R H Vaughan, Elisa Maillard, P A Bateman, Patrik Rorsman, Anju Abraham, Stephen J. Hughes, Mark J. Dunne, Bing Han, J D Johnson, S E Cross, Reshma Ramracheya, A.J. Willcox

Publikováno v: Cross, S E, Vaughan, R H, Willcox, A J, McBride, A J, Abraham, A A, Han, B, Johnson, J D, Maillard, E, Bateman, P A, Ramracheya, R D, Rorsman, P, Kadler, K, Dunne, M, Hughes, S J & Johnson, P R V 2017, ' Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation ', American Journal of Transplantation, vol. 17, no. 2, pp. 451-461 . https://doi.org/10.1111/ajt.13975
Europe PubMed Central

Clinical islet transplantation achieves insulin independence in selected patients, yet current methods for extracting islets from their surrounding pancreatic matrix are suboptimal. The islet basement membrane (BM) influences islet function and survi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de02888758293324059e1b52d37ac05
https://doi.org/10.1111/ajt.13975

Biological Activity of Ectodysplasin A Is Conditioned by Its Collagen and Heparan Sulfate Proteoglycan-binding Domains*

Autor: Laure Willen, Pascal Schneider, Aubry Tardivel, Manuel Favre, Lee Kim Swee, Stéphane Demotz, Marja L. Mikkola, Karine Ingold-Salamin, Olivier Gaide

Publikováno v: J Biol Chem
Journal of Biological Chemistry, Vol. 284, No 40 (2009) pp. 27567-27576
Journal of Biological Chemistry, vol. 284, no. 40, pp. 27567-27576

Mutations in the TNF family ligand EDA1 cause X-linked hypohidrotic ectodermal dysplasia (XLHED), a condition characterized by defective development of skin appendages. The EDA1 protein displays a proteolytic processing site responsible for its conve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068d6b13c26388b5d6b70474d33524c2
https://europepmc.org/articles/PMC2785685/

Vascular localization of heparan sulfate proteoglycans in retinas of patients with diabetes mellitus and in VEGF-induced retinopathy using domain-specific antibodies

Autor: A. N. Witmer, Gijs F.J.M. Vrensen, J. van den Born, Reinier O. Schlingemann

Publikováno v: Current Eye Research, 22(3), 190-197
Current eye research, 22(3), 190-197. Taylor and Francis Ltd.

PURPOSE: The Steno hypothesis (Deckert et al. ) states that in diabetes mellitus (DM), changes in vascular heparan sulfate proteoglycan (HSPG) expression are involved in systemic endothelial dysfunction and increased capillary permeability. In diabet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef76f561befff0d59e2e0d92cd602fa0
https://doi.org/10.1076/ceyr.22.3.190.5519

Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane

Autor: Lambert P. van den Heuvel, Karel J.M. Assmann, H. Dijkman, Thea J. van de Velden, Jacques H. Veerkamp, C.A.F. Buskens, Leo A. H. Monnens, Markus A. Rüegg, Alexander J. Groffen, Jacob van den Born

Publikováno v: Journal of Histochemistry & Cytochemistry, 46(1), 19-27
The Journal of Histochemistry and Cytochemistry, 46(1), 19-27. Histochemical Society Inc.
Groffen, A J, Ruegg, M A, Dijkman, H, Van De Velden, T J, Buskens, C A, Van Den Born, J, Assmann, K J, Monnens, L A, Veerkamp, J H & Van Den Heuvel, L P 1998, ' Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane ', Journal of Histochemistry and Cytochemistry, vol. 46, no. 1, pp. 19-27 . https://doi.org/10.1177/002215549804600104
Journal of Histochemistry and Cytochemistry, 46, pp. 19-27
Journal of the American Society of Nephrology, 8, A2396-A2396. Williams & wilkins
Groffen, A J, Ruegg, M A, Dijkman, H, Van De Velden, T J, Buskens, C A, Van Den Born, J, Assmann, K J, Monnens, L A, Veerkamp, J H & Van Den Heuvel, L P 1998, ' Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane ', The Journal of Histochemistry and Cytochemistry, vol. 46, no. 1, pp. 19-27 . https://doi.org/10.1177/002215549804600104
Journal of Histochemistry and Cytochemistry, 46, 19-27
Journal of Histochemistry and Cytochemistry, 46(1), 19-27. Histochemical Society Inc.
Journal of the American Society of Nephrology, 8, pp. A2396-A2396

Agrin is a heparan sulfate proteoglycan (HSPG) that is highly concentrated in the synaptic basal lamina at the neuromuscular junction (NMJ). Agrin-like immunoreactivity is also detected outside the NMJ. Here we show that agrin is a major HSPG compone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df1560e294b76afdd44f950898b0cc8
https://research.rug.nl/en/publications/53e993fe-67b6-4829-bcd6-17100348ffbf

APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa

Autor: Carine Bosshard, Eddy Roosnek, Thomas Matthes, Stéphane Durual, Pascal Schneider, Christophe P. Frossard, Rudolf H. Zubler, Christiane Favre, Olivier Donzé, Bertrand Huard, Samir Myit, Thomas Alexander Mckee, Carlo Chizzolini, Jean-Philippe Guyot

Publikováno v: Journal of Clinical Investigation, Vol. 118, No 8 (2008) pp. 2887-2895
Journal of Clinical Investigation, vol. 118, no. 8, pp. 2887-2895

The bone marrow constitutes a favorable environment for long-lived antibody-secreting plasma cells, providing blood-circulating antibody. Plasma cells are also present in mucosa-associated lymphoid tissue (MALT) to mediate local frontline immunity, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c2bc5d6ba999012859ec876cfe7d09
https://archive-ouverte.unige.ch/unige:1157