Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Heonuk Jeong"'
Autor:
Yan Zhang, Kiwako Mori, Heonuk Jeong, Junhan Chen, Yifan Liang, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Myopia is a global public health concern, with a higher prevalence in women than that in male. As the relationship between sex hormone and myopia remains unclear, we aimed to reveal the relationship between sex hormone and myopia by removing
Externí odkaz:
https://doaj.org/article/9dbb1fb298a74501bf96fbd881c6b140
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The choroid, a vascularized tissue situated between the retina and the sclera, plays a crucial role in maintaining ocular homeostasis. Despite its significance, research on choroidal abnormalities and the establishment of effective in vitro
Externí odkaz:
https://doaj.org/article/dcfdeebe4b214daf990371df8eae2dce
Autor:
Longdan Kang, Shin-ichi Ikeda, Yajing Yang, Heonuk Jeong, Junhan Chen, Yan Zhang, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara
Publikováno v:
Eye and Vision, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Background Recent studies have indicated a strong correlation between endoplasmic reticulum (ER) stress and myopia and that eyedrops containing the ER stress inducer tunicamycin (Tm) can induce myopic changes in C57BL/6 J mice. Therefore, th
Externí odkaz:
https://doaj.org/article/40cbfeb584774b5fad485b9437d35174
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Myopia is an abnormal vision condition characterized by difficulties in seeing distant objects. Myopia has become a public health issue not only in Asian countries but also in Western countries. Previously, we found that violet light (VL, 36
Externí odkaz:
https://doaj.org/article/c24fd9781f7f4386bfd1ca4e599843e2
Publikováno v:
PLoS ONE, Vol 19, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/cde8f3c857914add8a03e17468a99667
Autor:
Jing Hou, Kiwako Mori, Shin-ichi Ikeda, Heonuk Jeong, Hidemasa Torii, Kazuno Negishi, Toshihide Kurihara, Kazuo Tsubota
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Myopia is becoming more common across the world, necessitating the development of preventive methods. We investigated the activity of early growth response 1 (EGR-1) protein and discovered that Ginkgo biloba extracts (GBEs) activated EGR-1 i
Externí odkaz:
https://doaj.org/article/81573a02425740afbdca280adc8df774
Autor:
Shin-ichi Ikeda, Toshihide Kurihara, Xiaoyan Jiang, Yukihiro Miwa, Deokho Lee, Naho Serizawa, Heonuk Jeong, Kiwako Mori, Yusaku Katada, Hiromitsu Kunimi, Nobuhiro Ozawa, Chiho Shoda, Mari Ibuki, Kazuno Negishi, Hidemasa Torii, Kazuo Tsubota
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
he underlying mechanism of myopic axial elongation of the eyes has long been unknown. Here, the authors show that endoplasmic reticulum stress in the sclera and its sensor proteins, PERK and ATF6, are involved in myopic axial elongation
Externí odkaz:
https://doaj.org/article/abe2d08ccb054189bebfa5d5b0ad66d5
Autor:
Deokho Lee, Yohei Tomita, Yukihiro Miwa, Heonuk Jeong, Ari Shinojima, Norimitsu Ban, Shintaro Yamaguchi, Ken Nishioka, Kazuno Negishi, Jun Yoshino, Toshihide Kurihara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14711 (2022)
Cardiovascular abnormality-mediated retinal ischemia causes severe visual impairment. Retinal ischemia is involved in enormous pathological processes including oxidative stress, reactive gliosis, and retinal functional deficits. Thus, maintaining ret
Externí odkaz:
https://doaj.org/article/e6d6f342d7a84fd8a995d561e9aeab4f
Autor:
Deokho Lee, Heonuk Jeong, Yukihiro Miwa, Ari Shinojima, Yusaku Katada, Kazuo Tsubota, Toshihide Kurihara
Publikováno v:
PeerJ, Vol 9, p e11665 (2021)
Background Retinal ischemic stresses are associated with the pathogenesis of various retinal vascular diseases. To investigate pathological mechanisms of retinal ischemia, reproducible, robust and clinically significant experimental rodent models are
Externí odkaz:
https://doaj.org/article/c1bbab9617294733adbb96acf7c74b58
Autor:
Ziyan Ma, Heonuk Jeong, Yajing Yang, Xiaoyan Jiang, Shin‐ichi Ikeda, Kazuno Negishi, Toshihide Kurihara, Kazuo Tsubota
Publikováno v:
Ophthalmic and Physiological Optics. 43:558-565