Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Heon Goo, Lee"'
Autor:
Saqib Nizami, Do Y. Soung, Francis Y. Lee, Charla R. Fischer, Neel Patel, Jung Ho Back, Lee Song, Danielle K. Stamer, Hiroshi Minematsu, Hicham Drissi, Maya Mikami, Heon Goo Lee
Publikováno v:
Journal of Orthopaedic Research. 35:2658-2666
Osteoclasts play key roles in bone remodeling and pathologic osteolytic disorders such as inflammation, infection, bone implant loosening, rheumatoid arthritis, metastatic bone cancers, and pathological fractures. Osteoclasts are formed by the fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::175958affc24420be26cff5007664011
https://doi.org/10.1002/jor.23587
https://doi.org/10.1002/jor.23587
Autor:
Charla R. Fischer, Saqib Nizami, Philip B. Kaiser, Francis Y. Lee, Hanying Bai, Jocelyn T. Compton, Shim Rho, Jon-Michael E. Caldwell, Chandhanarat Chandhanayingyong, Anny Hsu, Neel Patel, Lee Song, Thomas R. Hickernell, Heon Goo Lee, Maya Mikami
Publikováno v:
Journal of Orthopaedic Research. 33:1474-1486
The osteoclast is an integral cell of bone resorption. Since osteolytic disorders hinge on the function and dysfunction of the osteoclast, understanding osteoclast biology is fundamental to designing new therapies that curb osteolytic disorders. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1a9b7b563a10da5ee15ac08221e6b0f
https://doi.org/10.1002/jor.22795
https://doi.org/10.1002/jor.22795
Autor:
Wanda Setlik, Deborah L. Gumucio, Karan Nagar, James G. Fox, Meenakshi Rao, Jean Phillipe Pradere, Michael Churchill, Yagnesh Tailor, Simon Renders, Sureshkumar Muthupalani, Heon Goo Lee, Nicholas A. Manieri, Mark Glaire, Andrew S. Giraud, Siddhartha Mukherjee, Tracy C. Grikscheit, Stefanie Gross, Richard A. Friedman, Bernhard W. Renz, Francis Y. Lee, Maximilian Reichert, Anil K. Rustgi, Daniel L. Worthley, Yoku Hayakawa, Yiling Si, Aysu Uygur, Abhinav Nair, Jared Carpenter, Samuel Asfaha, Ashley N. Martinez, Xiaowei Chen, Hongshan Wang, Peter A. Sims, Ajay Prakash, Mazen A. Kheirbek, Gerard Karsenty, Jon Michael Caldwell, Katherine D. Walton, Robert F. Schwabe, Alka Kolhe, Trevor A. Graham, Michael D. Gershon, Jocelyn T. Compton, Saqib Nizami, H. Paco Kang, Matthew G. Schwartz, Guangchun Jin, Timothy C. Wang, Daniel E. Levin, C. Benedikt Westphalen, Thaddeus S. Stappenbeck
Publikováno v:
Cell, vol 160, iss 1-2
PMC
Paediatrics Publications
PMC
Paediatrics Publications
The stem cells that maintain and repair the postnatal skeleton remain undefined. One model suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, chondrocytes, marrow stromal cells, and adipocytes, although the existence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0584b21d4cc6a0c685bd69e8d2f5e0
Autor:
George J. Rhodes, Thomas R. Kleyman, Daniel Flores, Cindy Else, Yu Liu, Bruce A. Molitoris, Rolando Carrisoza-Gaytán, Ruben M. Sandoval, Rajeev Rohatgi, Heon Goo Lee, Francis Y. Lee, Lisa M. Satlin
Publikováno v:
American Journal of Physiology-Renal Physiology. 307:F195-F204
An increase in tubular fluid flow rate (TFF) stimulates Na reabsorption and K secretion in the cortical collecting duct (CCD) and subjects cells therein to biomechanical forces including fluid shear stress (FSS) and circumferential stretch (CS). Intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f440f45f8b2386a0ae1eb39e1135b9bc
https://doi.org/10.1152/ajprenal.00634.2013
https://doi.org/10.1152/ajprenal.00634.2013
Autor:
Neel Patel, Heon Goo Lee, Thomas R. Hickernell, Chandhanarat Chandhanayingyong, Kyung Ok Kim, Francis Y. Lee, Anny C. Hsu
Publikováno v:
Journal of Orthopaedic Research. 32:848-854
Despite advancements in multimodality chemotherapy, conventional cytotoxic treatments still remain ineffective for a subset of patients with aggressive metastatic or multifocal osteosarcoma. It has been shown that pERK1/2 inhibition enhances chemosen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05cfd0b756d7c4fc5b454e2a15c20a07
https://doi.org/10.1002/jor.22598
https://doi.org/10.1002/jor.22598
Autor:
Charla R, Fischer, Maya, Mikami, Hiroshi, Minematsu, Saqib, Nizami, Heon, Goo Lee, Danielle, Stamer, Neel, Patel, Do, Yu Soung, Jung-Ho, Back, Lee, Song, Hicham, Drissi, Francis Y, Lee
Publikováno v:
J Orthop Res
Osteoclasts play key roles in bone remodeling and pathologic osteolytic disorders such as inflammation, infection, bone implant loosening, rheumatoid arthritis, metastatic bone cancers, and pathological fractures. Osteoclasts are formed by the fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3ea3eaaf4b337132127f6b1d506be54
https://pubmed.ncbi.nlm.nih.gov/28460421
https://pubmed.ncbi.nlm.nih.gov/28460421
Autor:
Kyung Ok Kim, Anny Hsu, Saqib Nizami, Mike J. Shin, Ayse B. Celil Aydemir, Heon Goo Lee, Francis Y. Lee, Kook Jin Chung, Hiroshi Minematsu, Christopher R. Jacobs
Publikováno v:
Biomaterials. 32:9197-9206
Wear particles at the host bone-implant interface are a major challenge for successful bone implant arthoplasties. Current understanding of aseptic loosening consists of macrophage-mediated inflammatory responses and increasing osteoclastogenesis, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d465c7a7e1a61017a4aceba7cf0bdab
https://doi.org/10.1016/j.biomaterials.2011.08.059
https://doi.org/10.1016/j.biomaterials.2011.08.059
Autor:
Neel, Patel, Saqib, Nizami, Lee, Song, Maya, Mikami, Anny, Hsu, Thomas, Hickernell, Chandhanarat, Chandhanayingyong, Shim, Rho, Jocelyn T, Compton, Jon-Michael, Caldwell, Philip B, Kaiser, Hanying, Bai, Heon Goo, Lee, Charla R, Fischer, Francis Y, Lee
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 33(10)
The osteoclast is an integral cell of bone resorption. Since osteolytic disorders hinge on the function and dysfunction of the osteoclast, understanding osteoclast biology is fundamental to designing new therapies that curb osteolytic disorders. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a973530f165cd991d4260488beebe97b
https://pubmed.ncbi.nlm.nih.gov/25428830
https://pubmed.ncbi.nlm.nih.gov/25428830
Autor:
Cindy Else, Francis Y. Lee, Daniel Flores, Rajeev Rohatgi, Lisa M. Satlin, Rolando Carrisoza, Heon Goo Lee
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99c4e654964cf9344f58474ffd079d8c
https://doi.org/10.1096/fasebj.27.1_supplement.1148.10
https://doi.org/10.1096/fasebj.27.1_supplement.1148.10
Autor:
Edwin R. Cadet, Hesham M. Tawfeek, Francis Y. Lee, Chandhanarat Chandhanayinyong, Peter Tang, Roya Shaji, Seok Hyun Kweon, Heon Goo Lee, Saqib Nizami, Jonathan H. Lee, Daniel S. Oh, Anny Hsu, Hana Goto
The interface between bone tissue and metal implants undergoes various types of mechanical loading, such as strain, compression, fluid pressure, and shear stress, from daily activities. Such mechanical perturbations create suboptimal environments at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d1ec4d5f0fa34b0219ef5e7da65523
https://europepmc.org/articles/PMC3602649/
https://europepmc.org/articles/PMC3602649/
