Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Henryk I. Trzeciak"'
Publikováno v:
Pharmacological Reports. 61:529-538
Apart from having written an inglorious chapter in the history of medicine, thalidomide is currently being intensely studied because of its multidimensional activity. The aim of this study was to examine the effects of thalidomide on the skeletal sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cdbaf4cd32efdbed71f6a36c49a93a
https://doi.org/10.1016/s1734-1140(09)70096-9
https://doi.org/10.1016/s1734-1140(09)70096-9
Autor:
Henryk I. Trzeciak, A. Małecki, Ewa Krzystanek, Joanna Siuda, Marek Krzystanek, Grzegorz Opala
Publikováno v:
Journal of Neural Transmission. 114:1033-1039
Phospholipase A(2) (E.C. 3.1.1.4, PLA(2)) plays an essential role in metabolism of membrane phospholipids, it is related to inflammatory reactions, secretion of amyloid precursor protein and activation of NMDA receptor after ischemia. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbd5b97ef9a3070bfd552283f6765ce
https://doi.org/10.1007/s00702-007-0669-9
https://doi.org/10.1007/s00702-007-0669-9
Autor:
Wioleta Kowalczyk, Izabela Derdowska, Adam Prahl, Bernard Lammek, Marcin Janecki, Samed Melhem, Henryk I. Trzeciak
Publikováno v:
European Journal of Medicinal Chemistry. 40:63-68
In this study, we described the synthesis and some pharmacological properties of four new analogues of arginine vasopressin (AVP). Two peptides are substituted in position 2 with l -1-naphthylalanine ( l -1-Nal) or its d -enantiomer and in position 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80ce4b5c0932082608a5a98b737de53
https://doi.org/10.1016/j.ejmech.2004.09.011
https://doi.org/10.1016/j.ejmech.2004.09.011
Publikováno v:
NeuroToxicology. 23:385-395
The aim of the present study was to establish whether aniracetam is capable of protecting cultured rat astrocytes against ischemic injury. Treatment of the cultures with aniracetam (1, 10 and 100 mM) during 24 h ischemia simulated in vitro significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0cb5d86bc6e08602013dae8bdb2142
https://doi.org/10.1016/s0161-813x(02)00084-0
https://doi.org/10.1016/s0161-813x(02)00084-0
Publikováno v:
NeuroToxicology. 23:19-31
The aim of the present study was to establish whether piracetam (2-pyrrolidon-N-acetamide; PIR) and vinpocetine (a vasoactive vinca alkaloid; VINP) are capable of protecting astrocytes against hypoxic injury. Using the model of astrocyte cell culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf75fa56cd774d79041ab1d95cbeb5b
https://doi.org/10.1016/s0161-813x(02)00004-9
https://doi.org/10.1016/s0161-813x(02)00004-9
Autor:
Henryk I. Trzeciak, Bożena Gabryel
Publikováno v:
Neurotoxicity Research. 3:205-221
Astrocytes play an important role in the homeostasis of the CNS both in normal conditions and after ischemic injury. The swelling of astrocytes is observed during and several seconds after brain ischemia. Then ischemia stimulates sequential morpholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1910790691af763cd1c87c7f69c8dc2c
https://doi.org/10.1007/bf03033192
https://doi.org/10.1007/bf03033192
Autor:
M Sobocińska, Marcin Janecki, Izabela Derdowska, Henryk I. Trzeciak, Ewa Konieczna, J Janecka, E Lempicka, W Kozik, Samed Melhem, Bernard Lammek
Publikováno v:
Journal of Pharmacy and Pharmacology. 52:1105-1112
In this study we describe the synthesis and some pharmacological properties of six new analogues of arginine vasopressin (AVP). Five of the peptides were substituted in position 2 with L-1-naphthylalanine (L-1-Nal) or D-1-naphthylalanine (D-1-Nal); o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff2f0bd02e101633b965d08dca8e27d
https://doi.org/10.1211/0022357001775038
https://doi.org/10.1211/0022357001775038
Autor:
Jacek Petrusewicz, Marek Krzystanek, Ewa Krzystanek, Henryk I. Trzeciak, Tomasz Debowski, Emilia Nowakowska, Franciszek Saczewski, Maria Gdaniec
Publikováno v:
Archiv der Pharmazie. 331:241-248
A series of novel N-(4,5-dihydroimidazol-2-yl )- 1,3-dihydrobenzimidazole derivatlves 2a-d. 3a-d and 4a-p were prepared and their structure was determined by IR and NMR spectroscopic data as well as X-ray analysis of carbonitrile 2a. The compounds we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc683ced60c4fcf48d7a831d5821abab
https://doi.org/10.1002/(sici)1521-4184(199807)331:7/8<241::aid-ardp241>3.0.co
https://doi.org/10.1002/(sici)1521-4184(199807)331:7/8<241::aid-ardp241>3.0.co
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience. 245:179-182
The effect of neuroleptics on phospholipase A2 (PLA2) activity in rat brain plasma membranes was studied. Chlorpromazine (10 mg/kg), fluphenazine (5 mg/kg), thioridazine (5 mg/kg), trifluoperazine (5 mg/kg), haloperidol (2 mg/kg), and sulpiride (100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d217cf3303f8b7bda53dde34f12c90c1
https://doi.org/10.1007/bf02193092
https://doi.org/10.1007/bf02193092
Autor:
Paweł Cieslik, Henryk I. Trzeciak, Anna Pudełko, Andrzej Małecki, Artur Kozłowski, Bożena Gabryel
Publikováno v:
Developmental Neuroscience. 17:292-299
ATP is a potential marker of cell vialibility and growth. The content of ATP and 3H-valine incorporation into proteins were measured and the morphometry was performed after antidepressant treatment of astrocytes cultured in vitro with or without dibu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d35e2fb50e35436ba74faa186e783a0
https://doi.org/10.1159/000111299
https://doi.org/10.1159/000111299